Impact of Stem Cell Donation on Donors' Health
Official title: Retrospective-prospective Observational Monocentric Study Evaluating the Impact of Stem Cell Donation on Unrelated and Related Donors' Health.
Run by Fondazione IRCCS Policlinico San Matteo di Pavia · NCT06905704 · Data updated 2026-11-12
This study looks at how donating stem cells affects the health and well-being of both related and unrelated donors over time.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years to 70 Years |
| Sex | All |
| Enrollment | 400 (estimated) |
| Sponsor | Fondazione IRCCS Policlinico San Matteo di Pavia Academic / other |
| Locations | 1 site (Pavia, Pavia) |
| Status | Recruiting |
| Started | February 3, 2023 |
| Main results expected | December 31, 2028 |
| Study ends | January 31, 2029 |
| Registry record updated | April 1, 2025 |
| Trial ID | NCT06905704 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are family and volunteer stem cell donors aged 18 years and older who meet medical evaluation criteria.
✕Probably not a fit
Patients under 18 years of age will not benefit from this study as they are excluded from participation.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study examines the health outcomes of both related and unrelated stem cell donors. It includes a retrospective analysis of donor management from 2016 to 2022 and will continue to monitor new donors over the next five years. The study aims to ensure safety and satisfaction among donors while addressing the lack of comprehensive data on related donor management. It follows national and international guidelines for donor eligibility and health assessments.
Why it matters
Potential benefit: If successful, this study could enhance the safety protocols and health monitoring of stem cell donors, leading to improved donor experiences and outcomes.
How similar studies have gone: While there is limited data on related donor management, other studies have successfully monitored unrelated donors, indicating potential for valuable insights in this area.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Family donors ≥18 years referred by the Hematology and Oncohematology Transplant Center Pediatric of the Foundation of Centro Donatori -SIMT, following the national and international guidelines after medical evaluation * Volunteer donors from IBMDR registry ≥18 years, following the national and international guidelines after medical evaluation Exclusion Criteria: * Donors 18 \< years
Where it's running
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Fondazione IRCCS Policlinico San Matteo di Pavia
Pavia, Pavia, Italy Recruiting
Study contacts
- Study coordinator: Claudia Del Fante, MD
- Email: c.delfante@smatteo.pv.it
- Phone: +390382503306
How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.