Impact of Stem Cell Donation on Donors' Health

Retrospective-prospective Observational Monocentric Study Evaluating the Impact of Stem Cell Donation on Unrelated and Related Donors' Health.

Fondazione IRCCS Policlinico San Matteo di Pavia · NCT06905704

This study looks at how donating stem cells affects the health and well-being of both related and unrelated donors over time.

Quick facts

Study typeObservational
Enrollment400 (estimated)
Ages18 Years to 70 Years
SexAll
SponsorFondazione IRCCS Policlinico San Matteo di Pavia (other)
Locations1 site (Pavia, Pavia)
Trial IDNCT06905704 on ClinicalTrials.gov

What this trial studies

This observational study examines the health outcomes of both related and unrelated stem cell donors. It includes a retrospective analysis of donor management from 2016 to 2022 and will continue to monitor new donors over the next five years. The study aims to ensure safety and satisfaction among donors while addressing the lack of comprehensive data on related donor management. It follows national and international guidelines for donor eligibility and health assessments.

Who should consider this trial

Good fit: Ideal candidates for this study are family and volunteer stem cell donors aged 18 years and older who meet medical evaluation criteria.

Not a fit: Patients under 18 years of age will not benefit from this study as they are excluded from participation.

Why it matters

Potential benefit: If successful, this study could enhance the safety protocols and health monitoring of stem cell donors, leading to improved donor experiences and outcomes.

How similar studies have performed: While there is limited data on related donor management, other studies have successfully monitored unrelated donors, indicating potential for valuable insights in this area.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Family donors ≥18 years referred by the Hematology and Oncohematology Transplant Center Pediatric of the Foundation of Centro Donatori -SIMT, following the national and international guidelines after medical evaluation
* Volunteer donors from IBMDR registry ≥18 years, following the national and international guidelines after medical evaluation

Exclusion Criteria:

* Donors 18 \< years

Where this trial is running

Pavia, Pavia

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Stem Cell Donors, stem cell donors, safety, transplantation

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.