Using Stellate Ganglion Block to Treat Arrhythmic Storm

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effectiveness and safety of Percutaneous Stellate Ganglion Block (PSGB) in patients experiencing an arrhythmic storm, which is characterized by multiple sustained ventricular arrhythmias within a 24-hour period that do not respond to standard antiarrhythmic medications. Patients who meet the inclusion criteria will undergo PSGB and will be monitored for changes in the number of defibrillations required before and after the procedure. The study is multicenter and includes both retrospective and prospective data collection over a short-term period of 24 hours. The aim is to gather evidence on the potential benefits of this neuromodulation technique in emergency situations.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* age ≥ 18 years,
* presence of arrhythmic storm defined as more than three sustained ventricular arrhythmias in 24 hours refractory to the standard medical treatment.

Exclusion Criteria:

* A previous history of cardiac sympathicectomy
* Having a neck judged unsuitable for the procedure (previous neck surgery, previous burns, presence of large scars, thyroid goiter)

Both the two approaches present in literature and commonly used for this technique are allowed for the study:

* The "anatomical" approach which consist in the identification of the Chassaignac's tubercle that represents the point of needle insertion
* The "echo-guided" approach Regardless to the approach (anatomical or echo-guided) the doctor will be able to choose, according to the clinical characteristics of the patients, whether to perform a single shot injection of anesthetic or a continuous infusion of anesthetic. In the second case a catheter will be left in place and connected to an infusion pump.

Where it's running

• A.O. SS. Antonio e Biagio e Cesare Arrigo di Alessandria.
  Alessandria, Al, Italy Recruiting
• Ospedale di Bentivoglio
  Bentivoglio, Bo, Italy Recruiting
• Ospedale Maggiore di Bologna
  Bologna, Bo, Italy Recruiting
• Cardiology Department, Fondazione IRCCS Policlinico San Matteo
  Pavia, Pv, Italy Recruiting
• Ospedale Civile
  Voghera, Pv, Italy Recruiting
• Ospedale Mater Salutis
  Legnago, Vr, Italy Recruiting

Study contacts

• Study coordinator: Simone Savastano, MD
• Email: s.savastano@smatteo.pv.it
• Phone: +39 0382501590

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.