Machine learning to distinguish EGPA from HES

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Researchers will collect clinical history, laboratory results, instrumental data, and blood samples from adults diagnosed with EGPA or HES at a single center in Pavia, Italy. The collected data will be processed and analyzed with machine learning algorithms to identify patterns and features that differentiate the two conditions and to develop models predicting treatment response. Participation involves informed consent and blood draws for laboratory assessment; no investigational drugs or therapeutic interventions are given. The ultimate aim is to produce an algorithmic tool that could support clinicians in making more accurate and timely diagnoses.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. 18 years of age or over
2. A diagnosis of EGPA or HES
3. Willing and able to give informed written consent, or willing to give permission for a nominated friend or relative to provide written informed assent if they are unable to do so because of physical disabilities

Exclusion Criteria:

1. Lack of a confirmed diagnosis of EGPA or HES.
2. Other causes of eosinophilia

Where it's running

• Fondazione IRCCS Policlinico San Matteo, SC Reumatologia
  Pavia, Italy Recruiting

Study contacts

• Study coordinator: Carlomaurizio Montecucco
• Email: carlomaurizio.montecucco@unipv.it
• Phone: 390382502948

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.