Evaluating genetic causes of out-of-hospital cardiac arrest

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to determine the prevalence of hereditary heart diseases in patients who experience out-of-hospital cardiac arrest (OHCA) in the Lombardy Region, particularly focusing on individuals aged 50 and younger. Blood samples will be collected during resuscitation to analyze genetic variants that may contribute to cardiac diseases. The study will also assess the arrhythmic risk for family members of the patients and refine the classification of uncertain genetic variants. Data will be integrated with patient characteristics and environmental factors to enhance understanding of the causes of OHCA.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* All the patients suffering from OHCA of medical etiology in Lombardy Region ≤50 years, for whom resuscitation manoeuvres was started by EMS (AREU)

Exclusion Criteria:

* Patients under 18 years old
* Patients with a non-medical cause of the cardiac arrest

Where it's running

• Fondazione IRCCS Policlinico San Matteo di Pavia
  Pavia, Pavia, Italy Recruiting

Study contacts

• Study coordinator: Enrico Baldi, MD
• Email: enrico.baldi@unipv.it
• Phone: +39 3293556062

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.