Improving tolerance to chemoradiotherapy in head and neck cancer patients with nutritional support

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This project evaluates the effectiveness of oral nutritional supplementation enriched with immunonutrients compared to a standard nutritional blend in enhancing tolerance to chemoradiotherapy in patients with head and neck cancer. The study is a randomized, controlled, open-label pilot involving two parallel treatment groups. It aims to assess how these nutritional interventions, combined with counseling, can improve nutritional status, quality of life, and treatment feasibility during chemoradiotherapy. The focus is on the potential benefits of high-protein, high-calorie mixtures that may modulate inflammation and support recovery.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* diagnosis of head-neck cancer
* indication to curative or adjuvant chemoradiotherapy
* availability to planned measurements and to written informed consent.

Exclusion Criteria:

* age \<18 years
* indication to or ongoing artificial nutrition
* refusal

Where it's running

• Fondazione IRCCS Policlinico San Matteo
  Pavia, Italy Recruiting

Study contacts

• Principal investigator: Riccardo Caccialanza, MD — Fondazione IRCCS Policlinico San Matteo
• Study coordinator: Riccardo Caccialanza, MD
• Email: r.caccialanza@smatteo.pv.it
• Phone: 0382501615

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.