CDK4/6 drugs for older women with breast cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an ambispective, longitudinal observational study based at Fondazione IRCCS Policlinico San Matteo di Pavia that collects both past medical records and prospective follow-up of patients treated with CDK4/6 inhibitors. The study will compare clinical efficacy and safety outcomes between older women (primarily ≥70 years) and younger women, while accounting for comorbidities, performance status, physiological age, and frailty. Data will come from routine clinical care rather than experimental interventions, and participants must be receiving active systemic treatment with a CDK4/6 inhibitor. The aim is to better reflect real-world results in an older population that is underrepresented in randomized trials.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* age over 18 years
* patients with solid tumours undergoing active systemic treatment with CDK4/6 for adjuvant disease

Exclusion Criteria:

* Patients who are unable to understand informed consent document

Where it's running

• Fondazione IRCCS Policlinico San Matteo di Pavia
  Pavia, Pavia, Italy Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.