How autoimmune atrophic gastritis develops and presents over time

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This single-center observational project at Fondazione IRCCS Policlinico San Matteo in Pavia will enroll adults diagnosed with autoimmune atrophic gastritis using the updated Sydney System and obtain written informed consent. Investigators will collect clinical history, histological and laboratory data (including markers of gastric autoimmunity and evidence of nutrient deficiencies) and document changes over time without giving experimental treatment. Patients with uncertain histopathology, active Helicobacter pylori infection, long-term proton pump inhibitor use, or atrophic pangastritis are excluded. The aim is to characterize the natural history, clinical features, and downstream effects of hypo-achlorhydria, including impacts on microbiota and systemic complications.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Male or female, age ≥18 years;
* AAG diagnosis is made according to the updated Sydney System criteria referring to a tertiary outpatient clinic dedicated;
* Signed written informed consent.

Exclusion Criteria:

* Patients with uncertain histopathological findings;
* Patients with persistent or active Helicobacter pylori infection;
* Patients with long-term proton pump inhibitor users and atrophic pangastritis

Where it's running

• Fondazione IRCCS Policlinico San Matteo, SC Medicina Generale 1
  Pavia, Pavia, Italy Recruiting

Study contacts

• Study coordinator: Emanuela Miceli, MD
• Email: e.miceli@smatteo.pv.it
• Phone: +390382503545

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.