Oxidative stress markers in adults with type 1 diabetes versus LADA.

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This is an observational study enrolling 75 adults with type 1 diabetes and 75 adults with latent autoimmune diabetes in adults (LADA), all aged 18–75 and recruited from the outpatient diabetes center at IRCCS Policlinico San Matteo. Participants undergo a single visit for medical history and blood sample collection to measure pro-oxidant and antioxidant markers (d-ROMs, BAP, OXY-Adsorbent, -SHp, anti-ROMs) using the FREE Duo analyzer. For newly diagnosed (incident) cases a follow-up visit at 3 months will compare changes in HbA1c with changes in the oxidative biomarkers. Secondary analyses will examine associations between biomarkers and glycemic control and whether biomarkers cluster differently by diagnosis.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Patients with with already known or newly diagnosed type 1 diabetes mellitus or LADA Patients aged ≥ 18 years and ≤ 75 years Patients of both sexes All patients will be selected among outpatients attending the Center of Diabetes and Metabolic Diseases of First Department of Internal Medicine, IRCCS Policlinico San Matteo Foundation.

Exclusion Criteria:

Patients refusing to sign informate consent.

Where it's running

• Fondazione IRCCS Policlinico San Matteo di Pavia
  Pavia, Pavia, Italy Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.