Parvovirus B19 in pregnancy and its effects on the baby
Official title: Parvovirus B19 Infection in Pregnancy: Clinical Manifestations and Fetus/Newborn Outcome
Run by Fondazione IRCCS Policlinico San Matteo di Pavia · NCT07338279 · Data updated 2026-11-12
This project follows pregnant women who get parvovirus B19 and their babies to see how often the infection causes problems for the fetus or newborn.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | Women only |
| Enrollment | 150 (estimated) |
| Sponsor | Fondazione IRCCS Policlinico San Matteo di Pavia Academic / other |
| Locations | 5 sites (Pavia, Lombardy and 4 other locations) |
| Status | Recruiting |
| Started | March 6, 2025 |
| Main results expected | March 2026 |
| Study ends | December 2027 |
| Registry record updated | January 13, 2026 |
| Trial ID | NCT07338279 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are pregnant women older than 18 years with confirmed parvovirus B19 infection and their newborns.
✕Probably not a fit
People without parvovirus B19 infection, those under 18, or those unable to attend follow-up at the participating hospitals are unlikely to benefit from this project.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
Researchers will collect clinical data from pregnant women over 18 with confirmed parvovirus B19 infection and from their neonates to determine the rate of intrauterine transmission and fetal/newborn complications. The study will record maternal risk factors, pregnancy outcomes, management interventions, and longer-term sequelae in infants. Data will be gathered at participating hospitals in Lombardy, Italy, and analyzed to identify factors associated with worse outcomes and to evaluate the effectiveness of current management approaches. As an observational registry, no experimental treatments are assigned.
Why it matters
Potential benefit: If successful, the findings could help clinicians better predict fetal risk, refine management strategies in pregnancy, and provide clearer counseling for affected families.
How similar studies have gone: Previous observational work has documented risks such as fetal hydrops and pregnancy loss after maternal parvovirus B19 infection, so this study builds on existing clinical knowledge rather than testing a novel therapy.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Pregnant women \>18 years with parvovirus B19 infection and their neonates. Exclusion Criteria: * None
Where it's running
-
Fondazione IRCCS Policlinico San Matteo
Pavia, Lombardy, Italy Recruiting -
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
Milan, Italy Recruiting -
ASST Fatebenefratelli Sacco
Milan, Italy Recruiting -
ASST degli Spedali Civili di Brescia
Brescia, Italy Not yet recruiting -
Fondazione IRCCS San Gerardo dei Tintori
Monza, Italy Not yet recruiting
Study contacts
- Study coordinator: Daniele Lilleri
- Email: d.lilleri@smatteo.pv.it
- Phone: +39 0382 502420
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.