Clinical trial Recruiting at 3 sites Observational Ages 18 and up Women only

Parvovirus B19 in pregnancy and its effects on the baby

Official title: Parvovirus B19 Infection in Pregnancy: Clinical Manifestations and Fetus/Newborn Outcome

Run by Fondazione IRCCS Policlinico San Matteo di Pavia · NCT07338279 · Data updated 2026-11-12

This project follows pregnant women who get parvovirus B19 and their babies to see how often the infection causes problems for the fetus or newborn.

More Pregnancy trials

Quick facts

Study typeObservational
Ages18 Years and up
SexWomen only
Enrollment150 (estimated)
SponsorFondazione IRCCS Policlinico San Matteo di Pavia
Academic / other
Locations5 sites (Pavia, Lombardy and 4 other locations)
StatusRecruiting
StartedMarch 6, 2025
Main results expectedMarch 2026
Study endsDecember 2027
Registry record updatedJanuary 13, 2026
Trial IDNCT07338279 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are pregnant women older than 18 years with confirmed parvovirus B19 infection and their newborns.

Probably not a fit

People without parvovirus B19 infection, those under 18, or those unable to attend follow-up at the participating hospitals are unlikely to benefit from this project.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

Researchers will collect clinical data from pregnant women over 18 with confirmed parvovirus B19 infection and from their neonates to determine the rate of intrauterine transmission and fetal/newborn complications. The study will record maternal risk factors, pregnancy outcomes, management interventions, and longer-term sequelae in infants. Data will be gathered at participating hospitals in Lombardy, Italy, and analyzed to identify factors associated with worse outcomes and to evaluate the effectiveness of current management approaches. As an observational registry, no experimental treatments are assigned.

Why it matters

Potential benefit: If successful, the findings could help clinicians better predict fetal risk, refine management strategies in pregnancy, and provide clearer counseling for affected families.

How similar studies have gone: Previous observational work has documented risks such as fetal hydrops and pregnancy loss after maternal parvovirus B19 infection, so this study builds on existing clinical knowledge rather than testing a novel therapy.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Pregnant women \>18 years with parvovirus B19 infection and their neonates.

Exclusion Criteria:

* None

Where it's running

  • Fondazione IRCCS Policlinico San Matteo
    Pavia, Lombardy, Italy
    Recruiting
  • Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
    Milan, Italy
    Recruiting
  • ASST Fatebenefratelli Sacco
    Milan, Italy
    Recruiting
  • ASST degli Spedali Civili di Brescia
    Brescia, Italy
    Not yet recruiting
  • Fondazione IRCCS San Gerardo dei Tintori
    Monza, Italy
    Not yet recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.