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Clinical trials and research at University of California, San Francisco

• 331Clinical trials
• 2796NIH research projects
• 2New in 30 days
• 30Countries

Newest trials

All recruiting trials (newest 150 of 331)

• Guiding Optimal Blood Pressure in Peritoneal Dialysis

  This pilot tests whether aiming for a lower systolic blood pressure target (<120 mmHg) is feasible and practical for adults with end-stage kidney disease on peritoneal dialysis, compared to a <140 mmHg target.

  Recruiting at 2 sites University of California, San Francisco · San Francisco, California and 2 other locations · NCT07910773

• Understanding how the orbitofrontal cortex guides approach vs. avoidance in depression

  This study tests how different parts of the orbitofrontal cortex influence whether people pursue rewards or risk loss, and whether this pattern is altered in Major Depressive Disorder.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07896343

• LIFU to Help Sleep and Amyloid Reduction in Older Adults with Cognitive Impairment

  A wearable ultrasound device (ATTN201) is being tested to see if it’s safe and easy to use for people 65 and older with mild cognitive impairment and amyloid buildup.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07866768

• Tics and Tourette's: Accelerated TBS rTMS in Teens and Adults

  This study tests whether a short, intensive course of inhibitory theta burst stimulation can help reduce tic symptoms in teens and young adults with Tourette syndrome or chronic tic disorders.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07839377

• Compare two bladder medicines and placebo for urgency incontinence in older women

  This study tests whether tolterodine ER or mirabegron help with urinary and aging-related outcomes in older women with urgency-predominant incontinence, compared with placebo.

  Recruiting Phase 4 University of California, San Francisco · San Francisco, California · NCT07829029

• Peer-led Dynamic Choice HIV Prevention for Women

  This trial tests a peer-led HIV prevention approach to see if it helps women at higher risk in Uganda better prevent HIV than standard care.

  Recruiting University of California, San Francisco · Kampala · NCT07787988

• Relaxation audio during breastfeeding to help newborn growth and mom’s well-being

  Researchers will test if listening to a relaxation audio during breastfeeding helps LBW babies grow and reduces maternal stress in a Ugandan setting.

  Recruiting University of California, San Francisco · Kampala · NCT07774793

• Biomarker study to understand Long COVID using VIPER

  This study tests biomarkers in people with Long COVID and those who recovered from COVID-19 to see how they can diagnose and track the condition over time.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07770022

• Psilocybin Therapy for MeUD and HIV

  This study tests whether a single psilocybin dose, paired with motivational support therapy, can help people with HIV and moderate-to-severe methamphetamine use disorder stop using methamphetamine.

  Recruiting Phase 2 University of California, San Francisco · San Francisco, California · NCT07756736

• Glaucoma screening follow-up survey incentives

  This sub-study tests whether offering a small gift card, a chance to win a larger prize, or no incentive helps people respond to a follow-up phone survey about glaucoma screening.

  Recruiting University of California, San Francisco · Oakland, California and 1 other locations · NCT07755748

• Restarting RAS inhibitors after AKI: a quick test in hospitalized adults

  This pilot study tests whether restarting renin-angiotensin system inhibitors early after acute kidney injury is feasible and safe in hospitalized adults already using these medicines.

  Recruiting Phase 4 University of California, San Francisco · San Francisco, California · NCT07734636

• How social, structural, and lifestyle factors relate to prostate cancer outcomes in diverse men

  This study looks at whether social and lifestyle factors help explain differences in prostate cancer outcomes among Black, Hispanic, and Asian men who have had a radical prostatectomy.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07690579

• Clemastine for Neonatal White Matter Injury

  This small, early-stage study tests whether the drug clemastine is safe to give by mouth to premature babies with white matter injury and how the body handles the drug.

  Recruiting Phase 1 University of California, San Francisco · San Francisco, California · NCT07688746

• Adaptive daytime DBS parameter optimization for people with Parkinson's disease

  This study tests if aMedtronic Percept adaptive DBS can dynamically adjust stimulation in people with Parkinson's who already have DBS hardware.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07682311

• Non-Invasive Low Intensity Focused Ultrasound Stimulation for Drug-Resistant Epilepsy

  This study tests whether low intensity focused ultrasound can help reduce seizures in adults with drug‑resistant epilepsy.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07680842

• Remote monitoring to see if home spirometry, oximetry, scales, and surveys help track ILD

  This study tests whether a combination of home monitoring devices and electronic surveys can be used effectively to detect meaningful changes in health for adults with fibrotic interstitial lung disease.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07673237

• Period Pills for menstrual regulation using a two-drug approach

  This study tests whether taking a combination of mifepristone and misoprostol can help people with a late or missed period, who do not want to confirm pregnancy.

  Recruiting Phase 4 University of California, San Francisco · Oakland, California and 1 other locations · NCT07671989

• Imaging with 89Zr-DFO-YS5 to detect cancer

  This study tests a new PET radiotracer, 89Zr-DFO-YS5, to see if it can show cancer sites in adults with nerve sheath tumors, bladder cancer, or other solid tumors.

  Recruiting Phase 1 University of California, San Francisco · San Francisco, California · NCT07664397

• Normal lung and heart function references for healthy US veterans who served in Southwest Asia

  This study tests whether healthy veterans aged 24–68 who did not have exposure to airborne hazards have normal lung and heart function values that can serve as reference standards.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07641413

• FDG PET/MRI to Find Painful Inflammation in the Patellofemoral Joint

  This study tests whether FDG PET/MRI can locate inflammation causing knee pain in people with patellofemoral joint osteoarthritis.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07625150

• Recovery after coma from serious brain injury or illness

  This observational study will follow adults who are unconscious due to a serious brain illness or injury to see what medical, neurological, psychological, and social factors are linked with recovery over time.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07614074

• Written vs Video Patient Education for Postmastectomy Breast Reconstruction

  This trial tests whether written materials, video materials, or both help patients better understand and feel more confident before their breast reconstruction consult, compared with no extra education.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07602374

• LI-SWT for Erectile Dysfunction: A single-arm study at UCSF

  This study tests whether light intensity shockwave therapy can help men with erectile dysfunction and aims to see which patients are likely to benefit.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07592533

• Narrative medicine workshops to support teens and young adults with anorexia nervosa (virtual)

  This program tests whether a six-week series of narrative medicine workshops can help 16–25-year-olds with anorexia nervosa express themselves, reflect, and build resilience.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07579442

• Erector spinae plane block to reduce post-operative pain after posterior spinal fusion in children

  This will try giving an erector spinae plane block with ropivacaine to see if it reduces pain and the need for opioid pain medicine after posterior spinal fusion in children with adolescent idiopathic or neuromuscular scoliosis.

  Recruiting Phase 3 University of California, San Francisco · San Francisco, California · NCT07561827

• Central microperimetry and radial OCT in geographic atrophy

  We will test whether central microperimetry and radial OCT scans can more accurately measure how geographic atrophy progresses toward the fovea in people with or at risk for GA from age-related macular degeneration.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07556406

• Body composition and outcomes after breast reconstruction

  This study will see if detailed body composition measurements can help predict complications after mastectomy with immediate breast reconstruction in adult women.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07546331

• Social media support groups to help teens and young adults quit vaping

  This pilot tries a social-media group program called the Quit the Hit Toolkit to help adolescents and young adults who vape stop using nicotine.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07540780

• Generative AI Education Tool for Breast Cancer Care

  Researchers are testing an AI-powered teaching tool to help adults with breast cancer understand their care while receiving treatment from UCSF physicians.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07512271

• Hyperpolarized carbon imaging to see if MS patients respond to anti-CD20 therapy

  This study tests whether hyperpolarized carbon MRI can predict which relapsing remitting MS patients will respond to anti-CD20 therapy.

  Recruiting Phase 2 University of California, San Francisco · San Francisco, California · NCT07510607

• Laser thermal therapy for young people with low-grade glioma

  This research will test whether laser interstitial thermal therapy (LITT) can stop or slow recurrent or progressive low-grade gliomas in children, adolescents, and young adults.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07506239

• Platelet-Rich Plasma from Two Different Systems in Knee Osteoarthritis

  This study compares PRP made by two FDA-approved machines to see if the platelets differ and whether injections help knee symptoms.

  Recruiting Phase 4 University of California, San Francisco · San Francisco, California · NCT07491367

• Pulsed Electric Field Ablation for Metastatic Breast Cancer

  This trial tests a one-time pulsed electric field ablation to treat superficial metastatic breast cancer lesions in adults, guided by imaging.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07487844

• Impact of dietary salt on skin sodium and inflammatory skin disease

  We’re testing whether lowering salt and taking salt tablets changes skin sodium and symptoms in eczema and psoriasis.

  Recruiting at 2 sites Phase 4 University of California, San Francisco · San Francisco, California and 1 other locations · NCT07487831

• Novel therapies for young people with recurrent ATRT (ATRT)

  This study tests new treatment combinations for children and young adults with recurrent or progressive ATRT to see if they are safe and effective.

  Recruiting at 3 sites Phase 2 University of California, San Francisco · San Francisco, California and 3 other locations · NCT07447076

• Low-sodium diet and salt tablets to see if eczema improves

  This study tests whether a low-sodium diet can lessen eczema symptoms in adults with atopic dermatitis, using a cross-over design with sodium tablets and placebo to see if salt intake changes skin sodium and severity.

  Recruiting at 2 sites Phase 4 University of California, San Francisco · San Francisco, California and 1 other locations · NCT07447063

• PEth-boosted brief intervention for alcohol use in people with HIV

  In this study, people with HIV who drink at risky levels are randomized to receive standard MOH counseling with or without a PEth blood test result to see if linking test results to counseling helps reduce drinking.

  Recruiting University of California, San Francisco · Mbarara · NCT07444359

• Atropine eye drops to reduce pain and posterior synechiae after vitrectomy

  We will test whether atropine 1% eye drops used after vitrectomy surgery reduce pain and lower the chance of posterior synechiae.

  Recruiting Phase 4 University of California, San Francisco · San Francisco, California · NCT07434635

• Measuring tongue and throat forces during direct laryngoscopy

  We will test whether measuring and then showing surgeons real-time forces on the tongue and throat during laryngeal surgery helps reduce postoperative pain, numbness, and taste changes in adults having direct laryngoscopy.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07434583

• Meningioma: How social factors and personal risks relate to health outcomes

  This study tests whether social and personal risk factors help explain differences in health outcomes for adults with meningioma.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07418775

• PVI Alone vs PVI Plus PWI and SVCI with PFA in Persistent AF

  This study tests whether adding posterior wall isolation and superior vena cava isolation to pulmonary vein isolation with pulsed-field ablation helps people with persistent atrial fibrillation stay in rhythm.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07405359

• Simplified, scalable 24-hour adaptive deep brain stimulation for Parkinson's disease

  This study will test whether a less invasive under‑scalp recording system can drive around‑the‑clock adaptive deep brain stimulation to help people with Parkinson's disease who have motor fluctuations or sleep problems.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07398157

• Ultrasound-guided transgluteal nerve block versus usual ER care for acute sciatica

  This test tries a transgluteal sciatic nerve block to see if it reduces pain better than usual emergency-room care for adults with acute sciatica.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07397117

• Biobank and Registry for Interventional Genomics at UCSF

  This biobank and registry collects genetic specimens and related data to see if gene-editing ideas can be matched to genetic conditions in patients and their families.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07396285

• Audio-based therapy to help anxiety in people with psoriasis

  This study tests whether a short audio therapy session can ease anxiety in adults with psoriasis.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07390487

• Psychedelics in Healthy Older Adults With Low Well-being

  This study tests whether psilocybin helps older adults with low well-being by looking at brain activity, inflammation, and body signals over about 3 months.

  Recruiting Phase 1 University of California, San Francisco · San Francisco, California · NCT07386730

• Oral Health Care During Pregnancy to Try to Improve Gum Health and Birth Outcomes

  This study tests two noninvasive ways to improve dental health for pregnant people with gum disease, to see if better oral care can help pregnancy outcomes.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07377344

• Open-label placebo plus usual care for pain after Bernese periacetabular osteotomy

  This test will see if giving open-label placebo pills alongside usual care helps adolescents and young adults (ages 13–40) manage post-operative pain and reduce opioid use after Bernese periacetabular osteotomy.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07373210

• Liothyronine with BIT chemotherapy for relapsed medulloblastoma in kids and young adults

  This study tests Liothyronine (L-T3) with a BIT chemotherapy regimen in children and young adults whose medulloblastoma has come back or progressed after standard treatment.

  Recruiting at 2 sites Phase 1/2 University of California, San Francisco · San Francisco, California and 2 other locations · NCT07346157

• Mittin intervention to improve contraceptive side effect counseling and follow-up in Addis Ababa

  Aims to see if the Mittin program helps women who use hormonal methods or copper IUDs in Addis Ababa better manage their contraception according to their preferences.

  Recruiting University of California, San Francisco · Addis Ababa · NCT07301281

• Adaptive deep brain stimulation in the cerebellum for spinocerebellar ataxia type 6

  This will see if an implanted adaptive deep brain stimulator placed in the cerebellum can reduce movement and balance problems in adults with SCA6 who still have symptoms.

  Recruiting University of California, San Francisco · San Francisco, California and 1 other locations · NCT07288437

• How menopause and HIV together affect cardiovascular disease risk in women.

  This study will see if menopause combined with HIV raises heart disease risk in women with HIV by examining risk factors, inflammation, body composition, and whole-body MRI.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07284082

• Health Advocate program for kids after liver transplant

  This trial tests a Health Advocate approach to help families of children who recently had a liver transplant access resources and navigate care.

  Recruiting at 2 sites University of California, San Francisco · San Francisco, California and 1 other locations · NCT07279350

• Hormone Replacement Therapy added to standard care for frozen shoulder in peri- or postmenopausal women

  This study tests whether adding hormone replacement therapy to standard treatment helps reduce pain and stiffness from frozen shoulder in peri- or postmenopausal women.

  Recruiting Phase 4 University of California, San Francisco · San Francisco, California · NCT07278323

• Tracking infections and inflammation in people with ME/CFS

  This project will try to see if ongoing infections or inflammation are linked to biological changes in adults with ME/CFS by collecting clinical data and biospecimens over time, with healthy volunteers for comparison.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07227441

• Metformin for recurrent Posterior Fossa Group A (PFA) ependymoma

  This will test whether the diabetes drug metformin can change tumor markers and slow disease in children and young adults with recurrent or progressive PFA ependymoma.

  Recruiting at 8 sites Phase 2 University of California, San Francisco · Birmingham, Alabama and 12 other locations · NCT07226453

• Colesevelam to help remove PFAS and other environmental toxins from firefighters

  This trial will test whether the oral medicine colesevelam can lower blood PFAS and urine toxin levels in male firefighters with high occupational exposure.

  Recruiting Phase 1/2 University of California, San Francisco · San Francisco, California · NCT07226440

• Weekly sauna visits to build offline connections for 19–22-year-olds

  This pilot will test whether attending a 2-hour sauna once a week for eight weeks can help reduce loneliness in 19–22-year-olds by providing a relaxed social setting.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07223099

• Using short selfie videos to measure walking and speech changes in people with MS

  This project will test whether short selfie videos taken by people with MS can reliably show walking and speech changes similar to what clinicians see in person.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07222618

• Disrupted sleep and irregular heartbeats in people with hypoglossal nerve stimulators

  This study will test whether turning a hypoglossal nerve stimulation (HGNS) device off for a night increases the chance of irregular heartbeats or short atrial fibrillation episodes in adults with obstructive sleep apnea who already have an HGNS implant.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07220525

• Aripiprazole and sensorimotor function in adults who stutter

  We will test whether a single 10 mg dose of aripiprazole versus placebo changes speech sensorimotor processing and improves fluency in adults who stutter.

  Recruiting Phase 1 University of California, San Francisco · San Francisco, California · NCT07215884

• Nightly external trigeminal nerve stimulation to reduce ADHD symptoms in children with autism

  This trial will test whether a small, nightly forehead patch that delivers external trigeminal nerve stimulation can reduce ADHD symptoms in children with autism.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07214545

• Personalized adaptive deep brain stimulation for severe opioid use disorder

  This study will test whether personalized deep brain stimulation guided by invasive brain mapping is safe and can reduce cravings and opioid use in adults with severe, treatment-resistant opioid use disorder.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07214467

• MucoCept-CVN: a vaginal Lactobacillus product to help prevent HIV

  This trial will test whether a modified vaginal Lactobacillus that produces an anti‑HIV protein is safe and can colonize the vagina in healthy premenopausal women.

  Recruiting Phase 1 University of California, San Francisco · San Francisco, California · NCT07181486

• Progressive Supranuclear Palsy Clinical Trial Platform

  This trial tests two investigational PSP treatments (AADvac1 and LM11A-31) to see if they are safe and help people with PSP compared to placebo.

  Recruiting at 5 sites Phase 2 University of California, San Francisco · Sun City, Arizona and 20 other locations · NCT07173803

• Community programs to increase RSV vaccination among Latino adults

  This project tests whether community health worker counseling combined with text-message reminders can get more Latino older adults vaccinated against RSV and whether asking younger Latino adults to talk with older friends and family increases those conversations about RSV vaccination.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07171164

• Symptoms from immune checkpoint inhibitor therapy for cutaneous melanoma

  We will follow adults with stage IIB–IV cutaneous melanoma who are receiving immune checkpoint inhibitors to see how their symptoms change over time and which factors are linked to worse symptom patterns.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07148245

• Extended tobacco support for people experiencing homelessness

  This program tests whether extending tobacco treatment to 6 months with pharmacist counseling, monthly nicotine replacement deliveries, and phone wellness coaching helps adults experiencing homelessness quit smoking compared with a 3-month package.

  Recruiting Phase 4 University of California, San Francisco · San Francisco, California · NCT07148232

• Combining Lutetium-177 PSMA targeted therapy with liver-directed treatment for prostate cancer spread to the liver

  This trial tests whether giving Lutetium-177 PSMA targeted radiation together with liver-directed treatments helps men with metastatic castration‑resistant prostate cancer that has spread to the liver and who progressed on prior androgen pathway inhibitors.

  Recruiting Phase 1 University of California, San Francisco · San Francisco, California · NCT07145177

• Using breath-hold methods with and without oxygen to improve liver MRI image quality

  This study will test whether holding your breath at end-expiration, with or without extra oxygen, improves abdominal MRI image quality in healthy adults ages 18–75.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07135401

• Trauma-informed smoking cessation support during pregnancy

  This project will test a trauma-informed smoking cessation program that combines the 4Rs with the 5As to help pregnant women who smoke and have histories of trauma.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07129590

• Personalized closed-loop deep brain stimulation for treatment-resistant Bipolar II depression

  This study will test a personalized closed-loop deep brain stimulation system to try to reduce depressive symptoms in adults with treatment-resistant Bipolar II disorder.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07127913

• reSTART: remote support to help men with HIV take their medication and reduce stimulant use

  This trial will test whether a remote program of positive messages, motivational support, and a home urine tenofovir self-test can help men with HIV who use stimulants remember their HIV medicines and lower their viral load.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07125235

• AI (Mirai)-guided supplemental MRI to find breast cancer in women at high Mirai risk

  This will test whether adding a screening breast MRI finds more cancers in women whose mammograms are flagged as high risk by the Mirai AI model.

  Recruiting at 2 sites University of California, San Francisco · San Diego, California and 3 other locations · NCT07121972

• CONNECT Multilingual: Helping Spanish and Cantonese Speakers Quit Smoking During Lung Cancer Screening

  This trial tests a multilingual version of the CONNECT program to help current adult smokers who speak Spanish or Cantonese quit smoking while undergoing lung cancer screening.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07111936

• Dabrafenib and trametinib dose-reduction for BRAF V600 low-grade glioma

  This trial tries to see if stopping or slowly lowering dabrafenib and trametinib after about 12–24 months works for people with BRAF V600–mutant low-grade glioma.

  Recruiting at 12 sites Phase 2 University of California, San Francisco · Birmingham, Alabama and 11 other locations · NCT07110246

• Outpatient recovery after acute kidney injury that required dialysis

  This pilot will test whether measuring residual kidney function at hospital discharge and sharing that information with patients and their outpatient nephrologists, plus guidance on monitoring and considering twice-weekly dialysis, helps adults who had acute kidney injury and still need dialysis after leaving the hospi

  Recruiting University of California, San Francisco · San Francisco, California · NCT07106151

• Fruit and vegetable vouchers to help children with MASLD and household food insecurity

  This program will try giving fruit and vegetable vouchers to families to see if children with MASLD who face food insecurity eat more produce and have better liver-related health.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07091539

• Transcutaneous spinal cord stimulation to enhance recovery after acute spinal cord injury

  Tests whether non-invasive electrical stimulation applied to the spine starting three days after a traumatic acute spinal cord injury is safe and can help people regain movement.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07090473

• Household food insecurity and MASLD in children and adolescents

  This research will see if household food insecurity is linked to worse MASLD in children and adolescents who have elevated ALT and are overweight or obese.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07090083

• Whole milk versus skim milk effects on cholesterol and blood sugar

  This trial will test whether drinking whole milk or skim milk for two months at a time changes cholesterol and insulin resistance in adults who regularly drink milk.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07087184

• Mail-delivered mouth rinse and saliva kits for HPV testing in people with HIV

  This project tests whether people living with HIV can collect mouth rinse and saliva samples at home, mail them in, and get HPV test results that match clinic-collected samples.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07087145

• Best starting dose of ropivacaine with fentanyl for epidural pain relief during labor

  This trial tests different starting doses of ropivacaine with fentanyl to see which one gives effective pain relief within 30 minutes for people in active labor.

  Recruiting Phase 3 University of California, San Francisco · San Francisco, California · NCT07076368

• Transcranial magnetic stimulation for teens with OCD

  This project will test two types of transcranial magnetic stimulation to see if they are safe, tolerable, and show early benefit for teenagers (13–17) with moderate-to-severe OCD who have not improved enough with usual treatments.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07065669

• Intra-arterial lidocaine and methylprednisolone for SAH-related headaches

  This study tests whether injecting lidocaine and methylprednisolone into the middle meningeal artery can lessen headaches after a subarachnoid hemorrhage in adults undergoing routine brain imaging.

  Recruiting Phase 2 University of California, San Francisco · San Francisco, California · NCT07054801

• Comparing Lutetium-177 and Actinium-225 PSMA-targeted radiation before prostatectomy

  This will test whether giving one of two PSMA-targeted radiation drugs (Lutetium-177 or Actinium-225) before prostate removal works differently in men with high or very high-risk localized prostate cancer.

  Recruiting Phase 1 University of California, San Francisco · San Francisco, California · NCT07054346

• Smokefree Family Living to help Chinese American households quit smoking and reduce third‑hand smoke

  This trial tests whether a tailored Smokefree Family Living program helps Chinese American smokers and their household members quit smoking and lower third‑hand smoke contamination in their homes.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07049757

• Agricultural livelihood support for pregnant women to improve food security and birth outcomes

  This program will test whether giving pregnant women farming supplies, training, and access to model farms can reduce household food insecurity and improve birth and infant health for women with and without HIV.

  Recruiting University of California, San Francisco · Nairobi · NCT07043647

• Zanzalintinib with a bone-strengthening agent for metastatic clear cell RCC with bone metastases

  This phase 2 trial tests zanzalintinib plus a bone-strengthening agent in adults with metastatic clear cell renal cell cancer that has spread to bone and progressed after 1–3 prior therapies, including IO therapy.

  Recruiting Phase 2 University of California, San Francisco · San Francisco, California · NCT07043608

• Combining online CBT-I with passive body heating using a sauna blanket for insomnia

  This study will see if adding passive body heating with a sauna blanket to digital CBT-I helps adults with insomnia fall asleep faster and sleep better over nine weeks.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07036705

• Prehab and Creatine/Whey Supplements in Cirrhosis-Related Frailty

  This study tests whether a digital prehabilitation app plus creatine and whey protein can help maintain muscle health in people with cirrhosis and frailty.

  Recruiting University of California, San Francisco · San Francisco, California · NCT07029243

• ctDNA-guided therapy for relapsed or refractory Hodgkin lymphoma using pembrolizumab with GVD

  This study tests a pembrolizumab-based regimen plus chemotherapy in adults with relapsed or refractory classic Hodgkin lymphoma to see if ctDNA can guide treatment response and consolidation choices.

  Recruiting Phase 2 University of California, San Francisco · Davis, California and 5 other locations · NCT07021989

• C3PO: Predicting tuberculosis recurrence with blood and sputum tests

  This project will test whether new blood and sputum-based tests can identify people who are likely to get tuberculosis again after finishing standard treatment.

  Recruiting at 2 sites University of California, San Francisco · Kampala and 2 other locations · NCT07018076

• Skin salt levels and their link to eczema in adults 50 and older

  This project will test whether diet and skin barrier problems affect salt levels in the skin and whether those salt levels relate to eczema in people aged 50 and older.

  Recruiting at 2 sites University of California, San Francisco · San Francisco, California and 1 other locations · NCT06998446

• Digital interventions to manage alcohol consumption and atrial fibrillation severity

  This study is testing whether using a special app and text messages to help people cut down or quit drinking alcohol can improve heart rhythm problems in those with atrial fibrillation.

  Recruiting University of California, San Francisco · San Francisco, California · NCT06995391

• Magnesium and nerve monitoring during thoracolumbar spine fusion

  We will see if giving intravenous magnesium during open thoracolumbar spine fusion changes motor-evoked potential monitoring in adults having the operation.

  Recruiting Phase 4 University of California, San Francisco · San Francisco, California · NCT06975072

• Discharge education video to reduce post-operative healthcare use after HoLEP

  This will test whether showing an educational discharge video to adults undergoing HoLEP reduces post-operative healthcare visits and improves patient satisfaction.

  Recruiting University of California, San Francisco · San Francisco, California and 2 other locations · NCT06975033

• IBIS interventions to encourage HIV retesting in Kenya and Uganda

  This project will test whether up to 12 low-cost behavioral 'nudge' messages can increase repeat HIV testing among people aged 15 and older at higher risk in rural Kenya and Uganda.

  Recruiting at 2 sites University of California, San Francisco · Mbita and 1 other locations · NCT06971367

• Using I-124 PET/CT to find metastatic thyroid cancer

  This will try I-124 PET/CT scans to see if they detect metastatic thyroid cancer better than the usual I-123 or I-131 scans in people treated for differentiated thyroid cancer.

  Recruiting Phase 2 University of California, San Francisco · San Francisco, California · NCT06961084

• Parathyroid tissue transplant into the forearm for chronic hypoparathyroidism

  This project will try transplanting donated parathyroid tissue into the forearm of adults with chronic hypoparathyroidism to raise PTH and help normalize their calcium and phosphorus levels.

  Recruiting Phase 1/2 University of California, San Francisco · San Francisco, California · NCT06961071

• Home-based exercise and behavioral training to reduce frailty before lung transplant

  A remote 8-week exercise and motivation program is tested in adults awaiting lung transplant to see if it is safe and helpful for frailty and physical function.

  Recruiting University of California, San Francisco · San Francisco, California and 3 other locations · NCT06960421

• Microbiome changes after daily ketone ester in healthy adults

  This tests whether taking a ketone ester every day for one week changes the gut microbiome in healthy adults aged 18–40.

  Recruiting University of California, San Francisco · San Francisco, California · NCT06954675

• Shamba Maisha: a household farming program to improve sexual and reproductive health for adolescent girls and young women in Western Kenya

  This project will try a household-level agricultural program (Shamba Maisha) with adolescent girls and young women (ages 15–19) and their caregivers in Western Kenya to see if improving food security reduces HIV and other STI risk and improves reproductive and mental health.

  Recruiting University of California, San Francisco · Kisumu · NCT06953310

• Probiotics to Treat Anal HSIL in HIV Patients

  In people with HIV who have anal HSIL, this study tests whether a probiotic called EXE-346 can help clear lesions or reduce progression, compared with placebo.

  Recruiting Phase 2 University of California, San Francisco · San Francisco, California and 1 other locations · NCT06949800

• Improving follow-up after an eye screening referral

  This trial tries text message or health worker reminders to help people referred after an eye screening get to their hospital appointment within 21 days.

  Recruiting University of California, San Francisco · San Francisco, California · NCT06943599

• Using 18F-TRX to image solid tumors

  This trial tests whether the 18F-TRX PET tracer can detect tumors in adults with advanced solid tumors such as high‑grade glioma, clear cell renal cell carcinoma, or metastatic castration‑resistant prostate cancer.

  Recruiting Phase 1 University of California, San Francisco · San Francisco, California · NCT06942104

• Pregnancy registry for women with chronic neurological conditions

  This study is collecting information and samples from pregnant women with chronic neurological conditions to see how pregnancy affects their health and their baby's development.

  Recruiting University of California, San Francisco · San Francisco, California · NCT06940323

• Twice-daily digital exercises to improve working memory and control in older adults

  This study tests whether two different digital training apps, used about 25–45 minutes a day for up to eight weeks, can help older adults (including those with mild cognitive impairment) improve working memory and inhibitory control.

  Recruiting University of California, San Francisco · San Francisco, California · NCT06918704

• Twice-daily digital memory training for older adults

  This study will test whether a web-based game-like memory training delivered on an iPad can improve long-term memory and inhibitory control in older adults, including those with mild cognitive impairment.

  Recruiting University of California, San Francisco · San Francisco, California · NCT06916221

• VO plus pembrolizumab for angiosarcoma

  This study tests whether injecting Vusolimogene Oderparepvec (VO) into tumors, together with pembrolizumab, can help people with advanced angiosarcoma who have already tried other immunotherapies.

  Recruiting Phase 2 University of California, San Francisco · San Francisco, California · NCT06898970

• Probiotic treatment for depression in adolescents

  This study is testing if a probiotic called Visbiome can help improve depression in teenagers and young adults by looking at changes in their brain and gut health.

  Recruiting Early Phase 1 University of California, San Francisco · San Francisco, California · NCT06898788

• PET imaging with [89Zr]DFO-starPEG for solid tumors

  We will test a new PET imaging tracer called [89Zr]DFO-starPEG in adults with measurable solid tumors to see if it highlights tumor uptake and is safe.

  Recruiting Phase 1 University of California, San Francisco · San Francisco, California · NCT06894745

• Automated insulin delivery during labor for pregnant people with type 1 diabetes

  This trial will test whether using an automated insulin delivery (AID) system during labor and delivery helps pregnant people with type 1 diabetes keep blood sugar in range, reduces newborn low blood sugar, and improves birth satisfaction compared with IV insulin.

  Recruiting at 3 sites University of California, San Francisco · Los Angeles, California and 2 other locations · NCT06883344

• Integrating social risk information into opioid treatment in the emergency department

  This study is testing a new tool that adds social risk information to help emergency department patients with opioid use disorder stick to their treatment plans better.

  Recruiting University of California, San Francisco · San Francisco, California · NCT06872190

• Treatment for children with Embryonal Tumor With Multilayered Rosettes

  This study is testing a combination of chemotherapy and radiation to see if it helps children with a specific type of brain tumor called ETMR live longer and stay healthy after treatment.

  Recruiting at 8 sites Phase 2 University of California, San Francisco · Birmingham, Alabama and 7 other locations · NCT06861244

• Glaucoma screening to improve health of at-risk Californians

  This project will try mobile telemedicine glaucoma screening using OCT, fundus photos, and tonometry for older Black and Hispanic adults and people with diabetes seen at community clinics to see if it finds more undiagnosed glaucoma than giving education or delaying screening.

  Recruiting at 2 sites University of California, San Francisco · Fremont, California and 2 other locations · NCT06854198

• CCR5 immune blockade to prevent primary graft dysfunction after lung transplant

  This trial will test whether the drug Maraviroc can prevent primary graft dysfunction in adults undergoing bilateral lung transplantation who have a PGD risk score greater than 50%.

  Recruiting Phase 2 University of California, San Francisco · San Francisco, California · NCT06853223

• Reactive Oxygen Species and Reproduction (ROAR)

  This study will see if oxidative stress levels in follicular fluid, blood, and sperm are linked to egg quality and IVF success for couples undergoing blastocyst culture with PGS.

  Recruiting University of California, San Francisco · San Francisco, California · NCT06831019

• Group education plus micronutrient supplements to reduce anemia in newly married women in Nepal

  This project will try group education with husbands and mothers-in-law plus daily multiple micronutrient supplements to reduce anemia in newly married, non-pregnant women under 25 in Nepal.

  Recruiting University of California, San Francisco · Kathmandu · NCT06810440

• Personalized exercise program for cancer patients

  This study is testing a personalized exercise program and support group for women with gynecologic cancer to see if it helps them feel better during treatment.

  Recruiting University of California, San Francisco · San Francisco, California · NCT06809933

• Investigating how transposable elements affect immune aging in sepsis patients

  This study looks at how certain genetic elements might affect the immune system and health outcomes in people with sepsis in the ICU.

  Recruiting University of California, San Francisco · San Francisco, California · NCT06809868

• Comparing two medications to prevent kidney injury after major surgery

  This study is testing which medication, norepinephrine or phenylephrine, works better to prevent kidney injury in adults having major surgery.

  Recruiting at 10 sites Phase 4 University of California, San Francisco · San Francisco, California and 9 other locations · NCT06802224

• Preventing CMV after receiving a CMV-positive donor kidney using daily antiviral pills or weekly blood monitoring

  This study will test whether taking daily antiviral pills for 200 days or doing weekly blood checks and treating only if the virus appears is better at preventing CMV disease in adults who get a kidney from a CMV-positive donor and are themselves CMV-negative.

  Recruiting at 6 sites Phase 3 University of California, San Francisco · San Francisco, California and 7 other locations · NCT06798909

• Examining Telehealth for Abortion Care and Health Equity

  This study tests how using telehealth for abortion care affects costs and follow-up for patients, especially those from underserved communities, compared to in-person visits.

  Recruiting University of California, San Francisco · Oakland, California · NCT06787274

• Remote pelvic floor yoga program for chronic pelvic pain

  This study tests whether a remote yoga program can help women with chronic pelvic pain feel better compared to a regular physical conditioning program.

  Recruiting University of California, San Francisco · San Francisco, California · NCT06778070

• Antibody-drug conjugates for first- and second-line treatment of metastatic HER2‑negative and triple‑negative breast cancer

  This prospective registry will collect real-world data to see how FDA-approved antibody-drug conjugates work as first- or second-line treatments for adults with metastatic HER2‑negative or triple-negative breast cancer.

  Recruiting at 3 sites University of California, San Francisco · San Francisco, California and 2 other locations · NCT06774027

• Effects of Alcohol Consumption on Atrial Fibrillation Episodes

  This study is testing whether drinking small to moderate amounts of alcohol affects how often people with paroxysmal atrial fibrillation have episodes of irregular heartbeats.

  Recruiting at 2 sites University of California, San Francisco · San Francisco, California and 1 other locations · NCT06754176

• Using a new dental treatment for cavities in adults

  This study is testing a new dental treatment for cavities in adults to see if it can safely help fix teeth without causing any harm.

  Recruiting University of California, San Francisco · San Francisco, California · NCT06727110

• Observing the effects of anti-IL1 therapies on flare activity in FOP patients

  This study is testing if using certain anti-inflammatory medications can help kids and teens with Fibrodysplasia Ossificans Progressiva manage their flare-ups and bone growth issues.

  Recruiting University of California, San Francisco · San Francisco, California · NCT06724562

• Technology-based motivational interviewing to help adults quit smoking

  This project will try a chatbot-based motivational interviewing coach to help adult primary care patients who smoke become ready to quit and create a personalized quit plan.

  Recruiting at 2 sites University of California, San Francisco · San Francisco, California and 1 other locations · NCT06713603

• Virtual coaching and social support to help maintain exercise after cardiac rehab

  This program tests whether adding virtual coaching and social support helps people 55 and older keep up physical activity after finishing cardiac rehabilitation.

  Recruiting University of California, San Francisco · San Francisco, California · NCT06701188

• Induction chemotherapy followed by guided radiation for EBV-related nasopharyngeal cancer

  This study is testing a new way to treat EBV-related nasopharyngeal cancer by using a special type of chemotherapy followed by targeted radiation to see if it can reduce side effects while still being effective.

  Recruiting University of California, San Francisco · San Francisco, California · NCT06682442

• Mobile smoking cessation program for Veterans undergoing surgery

  This study is testing a mobile program to help Veterans quit smoking before surgery by offering rewards for staying smoke-free.

  Recruiting University of California, San Francisco · San Francisco, California · NCT06678672

• Understanding the natural history of Sphingosine Phosphate Lyase Insufficiency Syndrome

  This study looks at how Sphingosine Phosphate Lyase Insufficiency Syndrome affects patients over time and tries to find patterns and markers that could help predict their health outcomes.

  Recruiting University of California, San Francisco · San Francisco, California · NCT06669949

• Couples problem-solving support for pregnant women with HIV and depression in Malawi

  This project will try couples problem-solving therapy to reduce depression and help pregnant women with HIV stick with their PMTCT treatment and care.

  Recruiting University of California, San Francisco · Zomba · NCT06659315

• Natamycin plus cyclosporine eye drops for fungal corneal ulcers

  This test tries adding cyclosporine eye drops to standard natamycin drops to see if people with fungal corneal ulcers get better vision.

  Recruiting Phase 3 University of California, San Francisco · San Francisco, California and 1 other locations · NCT06658002

• Impact of Automated Insulin Delivery on Pregnancy Outcomes

  This study looks at how using automated insulin delivery systems during pregnancy affects the health of both mothers with type 1 diabetes and their babies.

  Recruiting University of California, San Francisco · San Francisco, California · NCT06654713

• Patient Care Outreach, Navigation, Technology and Support (COUNTS) 2.0

  This project will test a multilingual virtual patient navigation portal to help English-, Chinese-, and Spanish-speaking adults with breast cancer or cardiovascular disease in underserved communities.

  Recruiting at 2 sites University of California, San Francisco · San Francisco, California and 1 other locations · NCT06648278

• Using naltrexone injections to prevent overdose deaths in stimulant users

  This study is testing if monthly naltrexone injections can help prevent overdose deaths from fentanyl in people who use stimulants like cocaine and methamphetamine.

  Recruiting Phase 2/3 University of California, San Francisco · San Francisco, California · NCT06633900

• Evaluating fatigue and molecular mechanisms in cancer patients undergoing combined chemotherapy and radiation therapy

  This study is testing how fatigue affects cancer patients getting both chemotherapy and radiation therapy, and whether certain genes and molecules are linked to how tired they feel during treatment.

  Recruiting University of California, San Francisco · San Francisco, California · NCT06633224

• Understanding how inflammation affects fear responses in PTSD

  This study is testing how short-term changes in the immune system affect fear responses in people with and without PTSD by giving them a vaccine or a placebo while they listen to sounds.

  Recruiting Phase 1 University of California, San Francisco · San Francisco, California · NCT06630884

• Exploring how psilocybin and its administration context affect mental well-being in healthy adults

  This study is testing how taking psilocybin in different settings affects the mental well-being of healthy adults who aren't feeling their best.

  Recruiting Phase 2 University of California, San Francisco · San Francisco, California · NCT06626139

• Using focused ultrasound to treat essential tremor

  This study is testing if low-intensity focused ultrasound can help reduce tremors in people with essential tremor by targeting specific areas of the brain.

  Recruiting University of California, San Francisco · San Francisco, California · NCT06610877

• Testing blood samples for cancer DNA in head and neck cancer patients

  This study is testing if checking blood samples for cancer DNA can help predict if head and neck cancer patients will have a relapse after their treatment.

  Recruiting University of California, San Francisco · San Francisco, California · NCT06606028

• Using advanced MRI to assess treatment response in pancreatic cancer

  This study is testing a new MRI technique to see if it can better predict how well treatment works for people with pancreatic cancer.

  Recruiting University of California, San Francisco · San Francisco, California · NCT06600906

• Caregiver training for screening malnutrition relapse in children

  This study is testing if training caregivers to measure their children's arm size can help catch malnutrition relapses in kids who have recently recovered from severe malnutrition.

  Recruiting University of California, San Francisco · Nouna · NCT06599580

• Improving telehealth access for low-income patients with diabetes

  This study is testing a new way to help low-income patients with diabetes use telehealth services better by providing coaching and support to both patients and clinics.

  Recruiting University of California, San Francisco · San Francisco, California · NCT06598436

• Measuring brain glucose use with deuterated glucose by MRS in glioma

  This study tests whether using deuterated glucose with 1H MRS can reveal how glioma brain tissue takes up and processes glucose.

  Recruiting University of California, San Francisco · San Francisco, California · NCT06594315

• Using wearable devices to prevent hospitalizations during cancer treatment

  This study is testing whether using wearable devices can help predict and prevent hospital visits for patients getting radiation therapy for cancer.

  Recruiting University of California, San Francisco · San Francisco, California · NCT06587100

• A digital tool to empower adults with congenital heart disease

  This study is testing a digital tool called 'Empower My Congenital Health' to see if it helps adults with congenital heart disease feel more confident and engaged in managing their health.

  Recruiting University of California, San Francisco · San Francisco, California · NCT06581484

Showing recruiting studies first, then the newest. Describe your situation to find the ones that fit you.

NIH-funded research (newest 40 of 2796)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• How cancer cells use exosomes to evade the immune system

  This study is looking at how cancer cells use tiny bubbles called exosomes to hide proteins that can keep your immune system from fighting the tumor, and by figuring this out, the researchers hope to help doctors understand why some people respond well to cancer treatments while others don’t, ultimately aiming to creat

  NIH research University of California, San Francisco · San Francisco, United States · NIH-9869561

• Reducing harm from smoking using electronic cigarettes

  This study is looking at whether using electronic cigarettes can be a safer option for people who smoke traditional cigarettes, by comparing the health effects and exposure to harmful substances between the two.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-9752505

• Understanding how knee pain and knee obesity and muscle loss affect knee osteoarthritis

  This project looks at how knee swelling, excess knee fat, and muscle loss relate to pain and structural changes in knee osteoarthritis in adults.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11644470

• Cutaneous opioid signals in skin inflammation

  A mentor-identified clinician-researcher at UCSF is studying how natural skin opioids regulate itch and pain in inflammatory skin conditions like eczema and hidradenitis, with plans to map where these opioids come from and how they affect skin nerves.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11640034

• Pooling international data to understand long-term bisphosphonate use and atypical femur fractures

  This project combines large patient datasets from multiple countries to understand how long-term bisphosphonate use relates to rare hip and thigh bone fractures, helping doctors and patients make safer treatment choices.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11638692

• Airway cell and immune cell talks in lung transplant failure

  This grant tests how airway cells and immune cells interact to drive chronic rejection after lung transplant, with the goal of slowing or preventing scar-like damage.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11629839

• Community and digital tools to reduce HPV and cervical cancer burden

  A nurse or health team will test a community-based, digital strategy to help girls and young women, especially in rural areas, get HPV vaccination and cervical cancer prevention services.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11628959

• Community and digital tools to reduce HPV and cervical cancer in women with HIV

  A community- and digital-technology program aims to help girls and young women, including those with HIV, get more HPV vaccination and cervical cancer prevention services.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11628958

• Pooling international data to understand long-term bisphosphonate use and atypical femur fractures

  A large study will combine data from several groups to better understand how long-term bisphosphonate use relates to atypical femur fractures and how this varies among different groups of people.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11624856

• Pooling international data to understand long-term bisphosphonate use and rare thigh fractures

  A large, collaborative study will combine patient data from several cohorts to understand how long-term bisphosphonate use relates to rare atypical femur fractures and to help doctors tailor osteoporosis treatment.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11624855

• California Labor Laboratory collaboration hub

  A large research collaboration aimed at advancing understanding of how labor and employment factors affect health, with potential benefits for patients through healthier work environments and informed policies.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11623425

• Rapid Diagnostics Development for TB (Episode 2)

  A national network project to speed up better TB tests that work in real-world clinics, especially where TB is most common.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11622548

• Immunotherapy for glioblastoma: advancing treatment and understanding

  A patient-friendly summary of a grant exploring new immune-based treatments for glioblastoma to improve options for people affected by this brain cancer.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11608606

• Rapid TB Diagnostics Development Network Episode 2

  A national network is testing and linking new TB diagnostic technologies with clinical sites to speed up accurate, affordable testing for people in high-burden regions.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11607822

• Rapid TB Diagnostics Development Network II for Better TB Tests

  A national network in TB-endemic areas will identify and test new TB diagnostic technologies so that people with TB can be diagnosed faster and treated more effectively.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11607821

• Faster TB tests for more people in high-burden countries

  A network-wide effort to identify and test new TB diagnostic tools so more patients can be diagnosed quickly and start treatment.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11607820

• Rapid TB Diagnostics Network to speed better tests for TB patients

  A national network will identify and connect promising TB diagnostic technologies with clinical sites to speed evaluation and ensure tests work well in real-world settings, especially where TB is most common.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11607819

• Rapid Diagnostics for TB: Faster, smarter tests for people in high-burden areas

  A network-backed effort to bring new TB diagnostic tools to patients in high-burden countries so they get diagnosed faster and treated effectively.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11607818

• Faster TB diagnostic options to help patients get timely tests and treatment

  A funded project at UCSF aims to speed up the development and evaluation of new TB diagnostic tests so patients in high-burden countries can be diagnosed quickly and start effective treatment.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11607817

• Rapid Diagnostics Development for TB, Episode 2 network

  A national network initiative to speed up new TB tests so patients in high-burden areas can get faster, more accurate diagnoses and better treatment.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11607816

• Fighting fibroids with single-cell data to find new drugs

  A study uses patient fibroid and normal tissue cells to find existing drugs that could be repurposed to treat fibroids, with tests in human cells and a mouse model.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11607753

• Understanding how CD4 T cells fuel schistosomiasis-related lung disease

  A study explores how specific immune cells and inflammatory signals in schistosomiasis may contribute to pulmonary hypertension in people affected by the disease.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11606580

• CD4 T Cells, Schistosoma, and Pulmonary Hypertension: Understanding How Immune Cells Drive Disease

  A human-health focused study uses a mouse model and human samples to explore how immune cells and inflammation may contribute to a lung blood vessel disease linked to schistosomiasis.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11606579

• CD4 T Cells and Schistosoma-Related Pulmonary Hypertension

  A study to understand how specific immune cells behave in a lung complication caused by schistosomiasis, with the goal of finding targets to prevent or treat it.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11606578

• In vivo stress-sensing microparticles to study tumor mechanics

  A new magnetic stress-sensing microparticle lets researchers watch how tumor tissues deform and change shape in real time, from small 3D cell clusters to live tumor models.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11605745

• NSR-SLEEP: Sleep and Resources in Children with Perinatal Brain Injury

  A study of children with perinatal brain injury, focusing on how sleep health and family resources relate to executive function in kids who may have ADHD-like symptoms.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11605229

• Calcium channel linked to familial advanced sleep phase and how it shifts our internal clock

  This project studies a genetic change in a calcium channel that may cause very early sleep times and waking times in families, with potential to guide future treatments for advanced sleep phase.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11604341

• Sjögren’s Team to Accelerate Medicines

  A team at UC San Francisco is coordinating a study to better understand Sjögren’s syndrome and speed up the development of better tests and treatments for people with the condition.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11601030

• Optimization of parasite genotyping to improve malaria therapy reports

  Researchers are improving how parasite DNA is used to judge whether antimalarial treatments work, focusing on people in sub-Saharan Africa who have falciparum malaria.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11597934

• UZ-UCSF CTU: Advancing HIV treatment and prevention through shared clinical trials

  A collaborative HIV-focused clinical trials unit in Zimbabwe and at UCSF works on multiple phases of HIV care and prevention to improve health outcomes.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11597193

• Understanding how immune cells and skin fibroblasts drive skin scarring

  A study at UC San Francisco will look at how CD8+ T cells and a special skin fibroblast population contribute to fibrosing skin diseases, with the goal of identifying targets to prevent scarring.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11596580

• Preclinical Design and Clinical Translation of TB Regimens for Faster TB Treatment

  A collaborative effort to find better TB treatment plans that could shorten therapy for people with TB by using early research findings to guide clinical steps.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11595892

• Liver pathobiology from rare liver diseases

  A study at UCSF looks at why rare liver conditions cause liver damage, with the aim of finding new ways to diagnose and treat chronic liver disease.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11594756

• Liver Cirrhosis Network: Longitudinal and Clinical Trial Studies

  A network-wide NIH study focused on understanding cirrhosis better to prevent complications and improve care for people with advanced liver disease.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11591424

• Understanding how people and mosquitoes interact to boost malaria control in Uganda

  Aimed at better malaria prevention, this project looks at how human and mosquito behaviors affect how well bednets and other tools work in Uganda.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11591363

• Fast, practical nudges to boost HIV retesting in at-risk adults

  A large, real-world study will test small, low-cost nudges to help adults at risk for HIV retest more often so they can get timely diagnosis and start treatment.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11590752

• Rapid HIV retesting: better ways to help adults at risk get tested more often

  A large, practical study from UC San Francisco tests simple, low-cost nudges to help adults at risk for HIV retest more regularly.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11590751

• Body composition and outcomes after lung transplant

  A patient-focused look at how body fat and muscle measurements around the time of lung transplant relate to recovery, complications, and quality of life after surgery.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11585360

• Post-TB lung disease in HIV patients: how common and what it looks like over time

  This study looks at how many people who survived TB have ongoing lung problems, what kinds of problems they are, and how HIV might change them, in a large group followed after TB treatment.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11581281

• Digital tool to reduce HIV-related stigma in Nepal HIV care centers

  A user-friendly digital tool helps clinics measure and reduce stigma related to HIV, mental health, and other factors to improve care for people living with HIV.

  NIH research University of California, San Francisco · San Francisco, United States · NIH-11578771

Quick answers

How many clinical trials run by University of California, San Francisco are recruiting right now?

331, as of November 12, 2026. 2 of them were first registered in the last 30 days. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 30 countries. The most sites are in United States (305 trials), Uganda (8 trials), Kenya (5 trials), India (4 trials), South Africa (4 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 41, Phase 1: 28, Phase 4: 22, Phase 1/2: 16. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →