Using a new dental treatment for cavities in adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to evaluate the safety of Polymer-Induced Liquid Precursor (PILP) in treating dentin caries in adults. Participants will receive either PILP or a placebo before having a filling placed in a carious tooth. The study involves multiple follow-up visits to monitor for any adverse effects over a six-month period. The primary focus is to determine if PILP can be safely used without causing harm to the tooth or the patient.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Stated willingness to comply with all study procedures and availability for the duration of the study
2. Male or female, aged 18 to sixty-four
3. In good general health as evidenced by medical history (ASA 1 or 2)
4. With at least one posterior tooth with caries to dentin

   1. The tooth must have a pulpal diagnosis of pulpal health (no irreversible pulpitis or periapical radiolucency)
   2. The tooth should have no existing restorations
   3. The caries should be a Class I or class V single surface lesion
   4. The tooth should be planned for restoration with intra-coronal restoration (composite or RMGI restoration)
   5. The tooth should be deemed as needing a restoration based on ICDAS (International Caries Detection and Assessment System)

Exclusion Criteria: Known allergic reactions to components of the study device

Where it's running

• University of California San Francisco, School of Dentistry
  San Francisco, California, United States Recruiting

Study contacts

• Principal investigator: Stefan Habelitz, PhD — Stefan Habelitz, PhD
• Study coordinator: Jean Star, DDS, MPH
• Email: jean.star@ucsf.edu
• Phone: 415-514-9768

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Dental health in children with specific learning disabilities

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  Recruiting Alanya Alaaddin Keykubat University · Alanya, Antalya · NCT07611981

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.