Body composition and outcomes after lung transplant
Official title: The impact of body composition on peri-operative and patient-centered outcomes in lung transplantation.
Funded at University of California, San Francisco · NIH-11585360 · Data updated 2026-11-12
A patient-focused look at how body fat and muscle measurements around the time of lung transplant relate to recovery, complications, and quality of life after surgery.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | August 5, 2022 |
| Project end | July 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $173,978 |
| NIH project number | 3U01HL163242-05S1 |
| Project ID | NIH-11585360 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults undergoing or being evaluated for lung transplantation.
✕Less likely to help
Patients not connected to lung transplant pathways or those without relevant body composition issues may see limited direct benefit.
What this research studies
This project explores how body composition, including obesity and muscle loss, influences perioperative complications, graft function, and long-term well-being for people undergoing lung transplantation. By using accessible measures like bioelectrical impedance and imaging, the research aims to identify patterns that predict worse outcomes and understand how these factors affect day-to-day functioning. The findings could help clinicians tailor pre- and post-transplant care to improve survival, reduce complications, and enhance patient-reported quality of life. Enrollees may contribute data and samples to better define who is at risk and how to optimize care.
Why it matters
Potential benefit: If successful, patients could benefit from personalized strategies to reduce risks and improve recovery and HRQL after lung transplantation.
How similar studies have gone: Prior work has linked obesity and sarcopenia to worse transplant outcomes, with newer methods like bioelectrical impedance improving assessment.
Where this research is happening
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University of California, San Francisco
San Francisco, United States Active
Researchers
- Principal investigator: Singer, Jonathan Paul — University of California, San Francisco
- Study coordinator: Singer, Jonathan Paul
Related research
Other NIH-funded projects on the same topics.
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Advanced body fat imaging to improve lung transplant outcomes
This project uses CT imaging of fat distribution to better predict who will do well with a lung transplant and when to list them, with the goal of improving survival after transplant.
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Body composition and outcomes after lung transplant
This study explores how body composition affects recovery and patient-reported well-being after lung transplantation.
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How body fat and muscle affect recovery after lung transplant
This project looks at how body fat and muscle mass relate to recovery, complications, and quality of life for people getting lung transplants.
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How body fat and muscle affect recovery and quality of life after lung transplant
This research looks at whether body fat, muscle mass, and related body-measure tests predict complications, survival, and quality of life for people getting lung transplants.
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How body composition affects outcomes in lung transplantation
This study is looking at how body weight and muscle health affect recovery and quality of life for people getting a lung transplant, so we can better support patients during their healing process.
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How body composition affects outcomes for lung transplant patients
This study is looking at how body weight and muscle mass affect the health and recovery of people getting a lung transplant, with the goal of helping doctors better care for their patients.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.