Integrating social risk information into opioid treatment in the emergency department

Using Clinical Decision Support to Provide Social Risk-Informed Care for Opioid Use Disorder in the Emergency Department

Not applicable Interventional University of California, San Francisco · NCT06872190

This study is testing a new tool that adds social risk information to help emergency department patients with opioid use disorder stick to their treatment plans better.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment300 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of California, San Francisco Academic / other
Locations1 site (San Francisco, California)
Trial IDNCT06872190 on ClinicalTrials.gov

What this trial studies

This study aims to enhance an existing clinical decision support tool by incorporating social risk information to improve medication treatment adherence for patients with opioid use disorder in the emergency department. It will evaluate the feasibility and acceptability of this enhanced tool compared to the original version at a single site, UCSF. The approach involves a mixed-methods, before-after design to assess the impact on treatment adherence and follow-up care for adult patients experiencing opioid use disorder.

Who should consider this trial

Good fit: Ideal candidates include English-speaking adults aged 18 and older presenting to the UCSF emergency department with opioid use disorder who receive medication treatment.

Not a fit: Patients with medical or psychiatric conditions requiring hospitalization, those who are actively suicidal, cognitively impaired, or presenting from extended care facilities may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to improved treatment adherence and better health outcomes for patients with opioid use disorder.

How similar studies have performed: Other studies have shown success with similar clinical decision support approaches, indicating potential for this method to improve treatment outcomes.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion criteria:

* All University of California, San Francisco ED providers (residents, attendings, advanced practice providers) who have used either CDSv1 or CDSv2 will be eligible to participate in surveys and interviews regarding feasibility and acceptability.
* English-speaking patients ≥18 years of age presenting to the UCSF ED with opioid use disorder who receive medication treatment (as a result of CDSv1 or CDSv2) will be eligible to participate.

Exclusion criteria:

\- Participants will be excluded if:

* they have a medical or psychiatric condition requiring hospitalization at the index ED visit,
* are actively suicidal, are cognitively impaired,
* present from an extended care facility, or
* require opioids for a pain condition.

Where this trial is running

San Francisco, California

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Opioid Use DisorderSocial Determinants of Healthsocial risk-informed careclinical decision supportopioid use disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.