Hormone Replacement Therapy added to standard care for frozen shoulder in peri- or postmenopausal women

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized, phase 4 trial compares hormone replacement therapy plus standard care to standard care alone for adhesive capsulitis in peri- or postmenopausal women. All participants receive physical therapy and a joint steroid injection; the experimental group also uses an HRT patch and daily pill. Outcomes include patient-reported shoulder function, range of motion, and a motion-analysis assessment over six months. The study aims to determine if hormonal support can improve pain, mobility, and daily function beyond standard care. Sixty eligible women will be enrolled and followed prospectively at UCSF.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Diagnosis of adhesive capsulitis of the shoulder

Exclusion Criteria:

* History of hormone sensitive cancer
* Bilateral adhesive capsulitis of the shoulder
* Currently using hormonal treatments including contraceptives

Where it's running

• UCSF Orthopaedic Institute
  San Francisco, California, United States Recruiting

Study contacts

• Principal investigator: Stephanie E Wong, MD — University of California, San Francisco
• Study coordinator: Alexa J Chandler, PhD
• Email: alexa.chandler@ucsf.edu
• Phone: (415) 353-2808

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.