Oral Health Care During Pregnancy to Try to Improve Gum Health and Birth Outcomes

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This interventional study compares two structured oral health interventions delivered to pregnant individuals with gingivitis or periodontitis. Enrollment is limited to less than 20 weeks of gestation and requires dental insurance and access to a mobile phone for messaging. Participants receive education, behavior guidance, and oral care products through enhanced care approaches, with outcomes including periodontal inflammation and potential effects on birth outcomes. The study is conducted at UCSF with collaboration from Colgate Palmolive and aims to address oral health disparities in underrepresented populations in California.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Pregnant individuals aged 18 years or older with indications of periodontal diseases (gingivitis or mild periodontitis, moderate to severe periodontitis)
2. Less than 20 weeks pregnancy at time of enrollment
3. Has dental insurance (Medi-Cal or private coverage)
4. Willing and able to provide informed consent
5. Planning to receive ongoing prenatal care at study-affiliated clinics
6. Access to a mobile phone for receiving text messages

Exclusion Criteria:

1. Presence of systemic diseases or medical conditions that require antibiotic prophylaxis for dental procedures
2. Current immunosuppressive therapy/use of anti-inflammatory medications
3. Receipt of active periodontal treatment within the past 6 months
4. Complete edentulism (no natural teeth)
5. Unable to read and write English
6. Less than 9th grade education
7. Enrollment in another oral interventional study

Where it's running

• UCSF Dental Center
  San Francisco, California, United States Recruiting

Study contacts

• Principal investigator: Effie Ioannidou, DDS, MDS — University of California, San Francisco
• Study coordinator: CHEER Study Manager
• Email: cheer@ucsf.edu
• Phone: 415-514-7900

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.