Glaucoma screening to improve health of at-risk Californians
Novel Telehealth Technologies to Detect and Manage Glaucoma and Vision-threatening Eye Diseases in High-risk Populations
This project will try mobile telemedicine glaucoma screening using OCT, fundus photos, and tonometry for older Black and Hispanic adults and people with diabetes seen at community clinics to see if it finds more undiagnosed glaucoma than giving education or delaying screening.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 2000 (estimated) |
| Ages | 50 Years and up |
| Sex | All |
| Sponsor | University of California, San Francisco Academic / other |
| Locations | 2 sites (Oakland, California and 1 other locations) |
| Trial ID | NCT06854198 on ClinicalTrials.gov |
What this trial studies
This is a randomized trial comparing a mobile, telemedicine-based glaucoma screening program (optical coherence tomography, color fundus photography, and tonometry) to an educational brochure or delayed intervention. Participants are drawn from Federally Qualified Health Centers in the San Francisco Bay Area and must meet age and risk-based inclusion criteria. The primary outcome is the number of new glaucoma diagnoses detected; secondary outcomes include rates of cataract surgery, distance vision correction, and vision-related quality of life at one year. Screening images and measurements are reviewed remotely by clinicians to guide referral and follow-up.
Who should consider this trial
Good fit: Ideal candidates are patients seen at participating FQHCs who are Black and at least 50 years old, Hispanic and at least 65 years old, or have diabetes and are at least 50 years old.
Not a fit: Patients who recently had an eye exam within the past year, lack a valid phone number or mailing address, live outside the participating clinics' service area, or already have a known glaucoma diagnosis may not get added benefit from this screening.
Why it matters
Potential benefit: If successful, the program could find glaucoma earlier in underserved patients and increase timely treatment to help prevent vision loss.
How similar studies have performed: Prior telemedicine and community-based glaucoma screening efforts using portable imaging and intraocular pressure have shown promise in increasing detection, but results and implementation have been variable across settings.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Black people aged 50 years or older * Hispanic people aged 65 years or older * People with diabetes aged 50 years or older * Must have been seen at the Federally Qualified Health Center (FQHC) within the past month Exclusion Criteria: * Patients without a valid phone number or mailing address * Patients who have had an optometry appointment within the past year
Where this trial is running
Oakland, California and 1 other locations
- Baywell Health — Oakland, California, United States (Recruiting)
- University of California, San Francisco — San Francisco, California, United States (Not_yet_recruiting)
Study contacts
- Principal investigator: Jeremy D Keenan, MD, MPH — University of California, San Francisco
- Study coordinator: Atnasia Mekonnen, MS
- Email: atnasia.mekonnen@ucsf.edu
- Phone: 510-603-3330
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.