Outpatient recovery after acute kidney injury that required dialysis
Official title: Outpatient Recovery From Acute Kidney Injury Requiring Dialysis - 2
Run by University of California, San Francisco · NCT07106151 · Data updated 2026-11-12
This pilot will test whether measuring residual kidney function at hospital discharge and sharing that information with patients and their outpatient nephrologists, plus guidance on monitoring and considering twice-weekly dialysis, helps adults who had acute kidney injury and still need dialysis after leaving the hospital.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | University of California, San Francisco Academic / other |
| Locations | 1 site (San Francisco, California) |
| Status | Recruiting |
| Started | February 23, 2026 |
| Main results expected | January 2028 |
| Study ends | January 2028 |
| Registry record updated | February 27, 2026 |
| Trial ID | NCT07106151 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Adults (≥18 years) with acute kidney injury requiring dialysis who are not known to have end-stage kidney disease and who are planned to continue dialysis after hospital discharge are ideal candidates.
✕Probably not a fit
People who are pregnant, incarcerated, unable to consent without a available surrogate, those whose clinical team declines participation, or patients with established end-stage kidney disease are unlikely to benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This pilot interventional study measures residual kidney function at the time of hospital discharge for adults with acute kidney injury who continue dialysis and communicates that result to the patient and the accepting nephrologist. Participants are assigned either to receive this additional AKI-D recovery information or to receive usual discharge information. The information package includes recommended recovery monitoring frequency and explicit criteria to consider a twice-weekly hemodialysis schedule during recovery. The study is designed primarily to test feasibility of measurement and communication and to observe whether this approach influences outpatient monitoring or dialysis scheduling.
Why it matters
Potential benefit: If successful, this approach could help identify patients who are recovering kidney function sooner and reduce unnecessary dialysis frequency or duration.
How similar studies have gone: Observational studies support using residual kidney function to guide recovery monitoring and dialysis frequency, but randomized or interventional evidence specifically testing discharge communication of these measures is limited, making this approach relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * AKI-D (not ESKD, as determined by the clinical inpatient nephrology team) * Age ≥ 18 years * Planned for continued dialysis outside the acute hospital setting (at outpatient dialysis unit/SNF/LTACH, not planned transfer to another short-stay acute care hospital). Exclusion Criteria: * Pregnant * Prisoner * Unable to consent and no surrogate decision maker available * Clinical team declines to allow approach for study
Where it's running
-
University of California, San Francisco
San Francisco, California, United States Recruiting
Study contacts
- Principal investigator: Ian E McCoy, MD, MS — University of California, San Francisco
- Study coordinator: Ian E McCoy, MD, MS
- Email: ian.mccoy@ucsf.edu
- Phone: 415-353-2507
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.