Effects of Alcohol Consumption on Atrial Fibrillation Episodes

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the short-term effects of minimal and moderate alcohol consumption on episodes of paroxysmal atrial fibrillation (AFib) in participants. Using a case-crossover randomized design, participants will be assigned daily to either avoid or consume alcohol over a 14-day monitoring period. They will wear various monitoring devices, including an ECG monitor and an alcohol monitor, while completing daily surveys to assess their alcohol intake and heart rhythm. The goal is to determine if allowing alcohol consumption increases the occurrence of AFib episodes.

Why it matters

Who can join: the full rules

Inclusion Criteria

* Comfortable reading and writing in English
* Have a smartphone and willing and able to use the Eureka mobile application
* Currently diagnosed with paroxysmal AFib without a plan to change their AFib management during the two-week monitoring period
* At least one episode of AFib in the past month OR, in the judgement of a healthcare provider, could potentially have one episode of AF in the next month
* Drank alcohol at least 1 day/week on average in the past month
* Willing and able to be randomly assigned daily to avoid or not avoid drinking alcohol over a 2-week period
* Willing and able to provide written informed consent

Exclusion Criteria

* Only post-operative AFib
* Greater than 40% ventricular pacing
* History of alcohol addiction or abuse determined by self-reported history or AUDIT-C score
* Intolerance to alcohol
* History of liver disease
* Currently incarcerated
* Currently pregnant or trying to get pregnant

Where it's running

• UCSF Medical Center at Parnassus
  San Francisco, California, United States Recruiting
• UCSF Medical Center at Mission Bay
  San Francisco, California, United States Recruiting

Study contacts

• Principal investigator: Gregory Marcus, MD, MAS — University of California, San Francisco
• Study coordinator: Gregory M Marcus, MD, MAS
• Email: greg.marcus@ucsf.edu
• Phone: 415-476-5706

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.