PEth-boosted brief intervention for alcohol use in people with HIV

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized feasibility study tests whether adding PEth biomarker feedback to a brief alcohol intervention is acceptable and feasible for people with HIV in Uganda. Eighty participants are evenly randomized to receive either the PEth-boosted brief intervention or the standard MOH brief counseling alone, with follow-up at 3 months. Primary outcomes focus on acceptability, appropriateness, and feasibility, using validated surveys. Secondary outcomes include readiness to reduce drinking, self-reported alcohol use, PEth levels, alcohol-related problems, and stigma. Data are collected via interviewer-administered surveys in English or Runyankole using REDCap.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 18 years and older;
* Resident in the study catchment area (\<60 km or \<2 hours travel);
* Fluent in Runyankole or English;
* Ability to give informed consent;
* Unhealthy alcohol use (AUDIT-C ≥3 for women, ≥4 for men, OR PEth≥20); ng/mL at a previous study visit or PERC screening);
* Having participated in a previous study, except for TRAC and PERC studies.

Exclusion Criteria:

* Having already participated in Aim 1 of this study;
* Having participated in the TRAC Study;
* Not fluent in English or Runyankole;
* Gross inebriation, cognitive impairment, or inability to provide informed consent.

Where it's running

• Mbarara Univeristy of Science and Technology
  Mbarara, Uganda Recruiting

Study contacts

• Principal investigator: Judith A Hahn, PhD, MA — University of California, San Francisco
• Study coordinator: Nneka I Emenyonu, DrPH, MPH
• Email: Nneka.Emenyonu@ucsf.edu
• Phone: 415-476-5815

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.