Community programs to increase RSV vaccination among Latino adults

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This type 1 hybrid-implementation effort partners community organizations with academic investigators to adapt and test outreach approaches using community-based participatory methods. In the Motivate phase, 400 Latino adults aged 50+ in San Francisco/Daly City are randomized across three arms (community health worker counseling plus text nudges, CHW-delivered RSV vaccine, or text nudges alone) and the primary outcome is RSV vaccine uptake. In a parallel Activate phase, 350 Latino adults aged 18–49 are randomized to CHW activation counseling plus text nudges versus text nudges alone, with the primary outcome the proportion of older contacts with whom participants discussed RSV vaccination. Both phases use culturally tailored interventions delivered in English or Spanish and measure implementation outcomes alongside effectiveness.

Why it matters

Who can join: the full rules

Motivate Aim Inclusion Criteria:

* Age 50 years or older
* Self-identify as Latino/a/x and/or indigenous groups from Latin America
* Eligible for RSV vaccination per current CDC/ACIP recommendations
* Fluent in Spanish or English
* Has not received the RSV vaccine
* Has a cell phone
* Lives or works in San Francisco or Daly City
* Able to provide informed consent

Motivate Aim Exclusion Criteria:

* Intent to move outside of San Francisco or Daly City in the next year
* Nursing home resident
* Household member participating in Aim 1 or 2
* Unable to provide consent

Motivate Aim Inclusion Criteria:

* Age 18-49 years
* Self-identify as Latino/a/x and/or indigenous groups from Latin America
* Fluent in English or Spanish
* Has \>1 family member or friend 50 years or older who they have seen or spoken to for \>15 minutes in the last 6 months and who lives in the United States

Activate Trial Exclusion Criteria:

* Household member enrolled in Aim 1 or 2
* Unable to provide consent

Where it's running

• University of California, San Francisco
  San Francisco, California, United States Recruiting

Study contacts

• Principal investigator: Carina Marquez, MD — University of California, San Francisco
• Study coordinator: RSV Uptake Study Coordinator
• Email: informatevrs@ucsf.edu
• Phone: 415-608-8339

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.