Faster TB diagnostic options to help patients get timely tests and treatment
Official title: Rapid Research for Diagnostics Development in TB Network: Episode 2 (R2D2 TB Network II)
Funded at University of California, San Francisco · NIH-11607817 · Data updated 2026-11-12
A funded project at UCSF aims to speed up the development and evaluation of new TB diagnostic tests so patients in high-burden countries can be diagnosed quickly and start effective treatment.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | September 11, 2025 |
| Project end | August 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $182,442 |
| NIH project number | 3R01AI190419-02S2 |
| Project ID | NIH-11607817 on NIH RePORTER |
Who could benefit from this research
✓Could help
Individuals in high TB burden regions who currently experience diagnostic delays or insufficient test performance.
✕Less likely to help
Patients in settings with already rapid, accurate TB testing or those not involved in diagnostic development may see limited direct benefit.
What this research studies
This grant supports identifying promising TB diagnostics and connecting developers with clinical study sites to test and refine them in real-world settings. It emphasizes evaluating tests across different use cases to meet WHO target profiles and improve performance in diverse health systems. The work focuses on collaboration between a biotechnology incubator, clinical centers, and a dedicated technology team to bring better diagnostics closer to patients who need them most.
Why it matters
Potential benefit: If successful, patients with TB could receive faster and more accurate diagnoses, leading to timely treatment and reduced transmission.
How similar studies have gone: Previous efforts show that multi-use diagnostics and rapid validation networks can improve TB detection, though the field still seeks faster, more affordable options.
Where this research is happening
-
University of California, San Francisco
San Francisco, United States Active
Researchers
- Principal investigator: Nahid, Payam — University of California, San Francisco
- Study coordinator: Nahid, Payam
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.