Smokefree Family Living to help Chinese American households quit smoking and reduce third‑hand smoke

Healthy Family Project: Ending Tobacco Use and Smoke Exposure in Asian American Communities

This trial tests whether a tailored Smokefree Family Living program helps Chinese American smokers and their household members quit smoking and lower third‑hand smoke contamination in their homes.

Quick facts

• Phase: Not applicable
• Study type: Interventional
• Enrollment: 760 (estimated)
• Ages: 18 Years and up
• Sex: All
• Sponsor: University of California, San Francisco (Academic / other)
• Locations: 1 site (San Francisco, California)
• Trial ID: NCT07049757 on ClinicalTrials.gov

What this trial studies

Smokefree Family Living (SFL) combines a culturally tailored Quit Smoking for a Healthy Family curriculum with third‑hand smoke (THS) education and home cleaning strategies. In a two‑arm randomized design the study plans to enroll 320 smoker–household member dyads from Chinese American communities and compare SFL to the original QS approach. Primary outcomes are smoking cessation at six months for smokers and reductions in THS exposure for non‑smoking household members, measured using urine specimens and silicone wristbands; interventions include educational sessions, telephone support, and SMS contact. Secondary and exploratory analyses will examine behavioral and social pathways, timing of THS intervention effects, and longer‑term outcomes in a 12‑month subsample.

Who should consider this trial

Good fit: Ideal candidates are Chinese or Chinese‑descent adults who smoke, live with at least one non‑smoking household member, can speak Cantonese, Mandarin, or English, and can attend sessions in person or by video and receive SMS or email contact.

Not a fit: People who are not Chinese/Chinese‑descent, are under 18, do not live with household members, are unwilling to participate in sessions or remote contact, or cannot comply with sample collection or follow‑up are unlikely to benefit from this intervention.

Why it matters

Potential benefit: If successful, SFL could raise quit rates among Chinese American smokers and lower household third‑hand smoke exposure, reducing exposure‑related health risks for family members.

How similar studies have performed: Culturally tailored, family‑focused smoking cessation programs like Quit Smoking for a Healthy Family have shown benefit in immigrant groups, but adding THS cleaning education and using silicone wristbands for THS measurement is a relatively new approach.

Eligibility criteria

Inclusion Criteria:

All Participants (Lay Health Workers, Smokers, Family Participants, and Post-Trial Household Member Group Interview Participants):

1. Must be 18 years of age or older.
2. Must self-identify as Chinese or of Chinese descent (ethnic or cultural identification, not national origin).
3. Must be able to understand in spoken Chinese (Cantonese and/or Mandarin) or English.
4. Able to attend educational sessions in person or via video conferencing.
5. Ability to understand and the willingness to sign a written informed consent document.
6. Have a mobile phone that can receive Short Message Service (SMS) text messages, or an email address and a phone number where they can be reached by the study team.

Lay Health Workers:

1. Must have experience or interest in community outreach and education.
2. Must demonstrate proficiency in language (Cantonese and/or Mandarin or English) sufficient to deliver study materials and interact with participants.
3. Must be affiliated with the Chinese Community Health Resource Center (CCHRC) or recruited through community networks.
4. Must agree to participate in training and intervention delivery activities as outlined in the study protocol.

Smokers (Participants who are current smokers):

1. Must have smoked within the past 30 days, either daily or occasionally.
2. Must have a non-smoking household member.

Family Participants (Non-smoking family/household members):

1. Must live in the same household as the smoker participant.
2. Must not have used any tobacco products in the past 30 days.

Post-Trial Household Member Group Interview Participants:

1\. Living in the same household with the smoker-household member dyad participant being interviewed or considered as a household member.

Exclusion Criteria:

Lay Health Workers, Smokers (Participants who are current smokers) and Family Participants (Non-smoking Family/household members):

1. Currently participating in another smoking cessation program.
2. Non-residents of California.
3. Participants unwilling to provide follow-up contact for assessments at 6 and 12 months.

Lay Health Workers:

1. Lack of willingness or ability to complete training or deliver intervention sessions as required by the study protocol.
2. Inability to maintain confidentiality and professionalism during interactions with study participants.
3. Active participation in conflicting research studies or programs.

Where this trial is running

San Francisco, California

• University of California, San Francisco — San Francisco, California, United States (Recruiting)

Study contacts

• Principal investigator: Janice Tsoh, PhD — University of California, San Francisco
• Study coordinator: Edgar Yu

Conditions Tobacco-Related Carcinoma; Smoking Cessation; Third-hand Smoke