Sponsor or institution

Clinical trials and research at University of Maryland Baltimore

• 93Clinical trials
• 812NIH research projects
• 3Countries

Newest trials

All recruiting trials (93)

• Time-restricted eating to help energy and fatigue in prostate or metastatic breast cancer

  This study tests whether eating all daily calories within a fixed window can improve energy and reduce frailty for adults with certain cancers who have fatigue.

  Recruiting Phase 2 University of Maryland, Baltimore · Baltimore, Maryland · NCT07826871

• Adaptive Chemotherapy for PD-L1 High Resectable NSCLC: A Chemo-PHREE Trial

  This study tests cemiplimab in adults with resectable non-small cell lung cancer to see if surgery can be pursued without preceding chemotherapy for some patients.

  Recruiting Phase 2 University of Maryland, Baltimore · Indianapolis, Indiana and 4 other locations · NCT07746388

• Virtual reality options to help with VOC pain in adults with SCD

  This study tests whether headset-based virtual reality can help reduce pain for adults with sickle cell disease during vaso-occlusive crises treated in an infusion center.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland · NCT07674277

• Gut permeability and microbiome in preterm infants

  This study tests a dual sugar probe test to measure gut permeability in very preterm babies to understand their risk for serious gut disease.

  Recruiting Phase 1 University of Maryland, Baltimore · Baltimore, Maryland · NCT07667049

• Recovery after mild traumatic brain injury in older adults

  This project will follow people 65 and older who had a mild TBI to see how their thinking, physical abilities, mood, and sleep change over the year after injury.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland · NCT07569354

• Biopsy-based test to compare wedge resection vs. radial incision for benign tracheal narrowing

  This study tests two airway-opening techniques in people with benign tracheal stenosis to see how their airway tissue changes after treatment.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland · NCT07463742

• Selective dose reduction of neck radiation in HPV-associated oropharyngeal cancer

  This trial tests whether lowering radiation doses to certain neck lymph nodes or gross disease areas is safe and can reduce side effects for adults with HPV-related oropharyngeal cancer.

  Recruiting at 4 sites Phase 2 University of Maryland, Baltimore · Baltimore, Maryland and 3 other locations · NCT07418034

• Radiation therapy options compared for newly diagnosed gynecologic cancers

  This study tests whether proton therapy works as well as conventional photon therapy for endometrial and cervical cancers.

  Recruiting at 5 sites Phase 2 University of Maryland, Baltimore · Baltimore, Maryland and 4 other locations · NCT07415681

• Motion tracking during lung cancer radiotherapy using real-time MRI

  A trial tests real-time tracking of lung tumor motion during radiation therapy in adults with certain stages of NSCLC to see if MRI can help guide treatment.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland · NCT07398209

• Fostering Positive Interactions Between Staff and Residents in Assisted Living

  This study tests a four-step approach to help staff in assisted living sites interact more positively with residents who have dementia.

  Recruiting University of Maryland, Baltimore · Columbia, Maryland and 2 other locations · NCT07378800

• Pelvic Ring Fragility Fractures: Are Surgery or No Surgery Better for Older Adults?

  This study tests whether surgical stabilization or nonoperative care is best for fragility pelvic fractures in adults 60 and older, by seeing if patients and surgeons would participate in a randomized trial and by checking data collection feasibility.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland · NCT07351123

• RNA sequencing of removed tracheal tissue to characterize scarring in tracheal and subglottic stenosis

  This project will test whether RNA sequencing of tissue removed from people with benign tracheal or subglottic stenosis can reveal molecular patterns that explain the scarring.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland · NCT07258784

• Home-based FES for shoulder adhesive capsulitis

  This study tests whether adding home-based functional electrical stimulation (FES) to standard therapy can reduce pain and improve shoulder function in adults with adhesive capsulitis.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland · NCT07227662

• Nerve blocks before surgery for older adults with lower leg fractures

  This will test whether giving a peripheral nerve-block injection before surgery helps people aged 50 and older with lower leg fractures recover with fewer complications and less opioid use.

  Recruiting Phase 4 University of Maryland, Baltimore · Baltimore, Maryland · NCT07217626

• Preserving ability through virtual reality exercise (PAVE)

  This project will test whether short virtual reality exercise sessions during a hospital stay help adults 55 and older keep their strength, mobility, and mood.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland · NCT07189286

• Ketone supplements to help curb opioid cravings during withdrawal

  This study tests whether taking a ketone supplement three times daily for seven days can reduce opioid cravings and withdrawal symptoms in adults with opioid use disorder who are staying at a treatment center.

  Recruiting Phase 2 University of Maryland, Baltimore · Wernersville, Pennsylvania · NCT07128524

• Biotivity A/C Plus Membrane for Alveolar Ridge Preservation after Tooth Extraction

  This study tests whether a human amnion chorion membrane helps healing and bone preservation better than a collagen membrane after extracting a back tooth and preparing the site for an implant.

  Recruiting Phase 4 University of Maryland, Baltimore · Baltimore, Maryland · NCT07091448

• Barriers to adopting a vegetarian diet in urban adults with chronic disease

  See how open urban adults with chronic disease are to trying a vegetarian diet and what stops them.

  Recruiting at 3 sites University of Maryland, Baltimore · Baltimore, Maryland and 2 other locations · NCT07075653

• Subcutaneous daratumumab in the thigh versus the abdomen for adults with plasma cell disorders

  This trial tests whether giving subcutaneous daratumumab in the thigh instead of the abdomen is safe and gives similar blood levels in adults with multiple myeloma or AL amyloidosis starting daratumumab.

  Recruiting Phase 1/2 University of Maryland, Baltimore · Baltimore, Maryland · NCT07075510

• Support for psychiatric clinics to increase prescribing of medicines for alcohol use disorder

  This project will test whether providing outside facilitation, training, and clinic-level supports in three psychiatric clinics helps clinicians prescribe medications for people with major mental illness who also have alcohol use disorder.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland · NCT07053098

• Daily broccoli microgreens for breast cancer survivors with obesity

  This two-week test will see if eating one cup of fresh broccoli microgreens each day is doable and changes metabolism and gut health in obese breast cancer survivors.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland · NCT07032545

• Developing and validating a blood test that reads DNA methylation to diagnose lung cancer

  This project will test a blood test that looks at DNA changes to see if it can detect lung cancer in people being screened or treated.

  Recruiting University of Maryland, Baltimore · Glen Burnie, Maryland · NCT07008664

• Measuring corneal stiffness in glaucoma with Brillouin microscopy

  We will use Brillouin microscopy to see if corneal stiffness differs between adults with normal-tension glaucoma, high-tension glaucoma, and people without glaucoma, and whether stiffness changes after common IOP-lowering eye drops.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland · NCT06993597

• Low-dose ketamine to reduce opioid craving in people starting methadone

  This test gives adults starting methadone either a low or very low dose of ketamine to see if it reduces opioid craving and withdrawal symptoms.

  Recruiting Phase 2 University of Maryland, Baltimore · Baltimore, Maryland · NCT06943859

• Smart insulin pens with CGM and telemedicine to improve blood sugar control in veterans with diabetes

  This trial will see if using smart insulin pens together with continuous glucose monitors (CGMs) and telemedicine helps veterans on multiple daily insulin injections control their blood sugar better than standard insulin pens with CGMs and telemedicine.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland and 1 other locations · NCT06918977

• Registry and biobank for ocular complications from cancer therapy

  This study is collecting information and samples from cancer patients to see how their treatment might cause eye problems, helping to better understand and predict these issues.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland · NCT06874283

• Retinal OCT biomarkers for ublituximab response in relapsing MS

  We will test whether special retinal OCT scans can find signs of immune activity in people with relapsing MS who are starting ublituximab or already on a stable MS medication.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland · NCT06864936

• Neoadjuvant chemoimmunotherapy with targeted SBRT for borderline resectable non-small cell lung cancer

  This trial will test whether giving focused radiation before standard chemoimmunotherapy and planned surgery helps people with borderline resectable non-small cell lung cancer.

  Recruiting at 4 sites Phase 1 University of Maryland, Baltimore · Baltimore, Maryland and 3 other locations · NCT06800339

• UMMS SEPSys sepsis prediction and RESCUE deterioration risk scoring for adult inpatients

  This project will test two four-hour risk scores that alert hospital providers about adult inpatients' near-term risk of developing sepsis or sudden clinical deterioration.

  Recruiting at 6 sites University of Maryland, Baltimore · Baltimore, Maryland and 7 other locations · NCT06779617

• Volunteering in Place Program for apathetic residents with dementia in assisted living

  This study tests whether volunteering in the community or a guided current events group can reduce apathy in adults with mild-to-moderate dementia living in assisted living facilities.

  Recruiting at 2 sites University of Maryland, Baltimore · Catonsville, Maryland and 1 other locations · NCT06735950

• Near‑infrared photobiomodulation for pain relief during children's dental care

  This will test a non‑invasive near‑infrared light device to reduce tooth and gum pain and potentially avoid injections for children aged 6–12 undergoing routine dental care.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland · NCT06691269

• Exploring how music training can improve brain function in schizophrenia

  This study tests whether playing a music video game can help improve brain function in young people with schizophrenia by changing the way their brain is wired.

  Recruiting University of Maryland, Baltimore · Catonsville, Maryland and 1 other locations · NCT06641297

• Evaluating the Gardasil HPV vaccine's immune responses in people with and without HIV

  This study is testing how well the Gardasil HPV vaccine works in people born male, both with and without HIV, to see how their immune systems respond to the vaccine.

  Recruiting Phase 2 University of Maryland, Baltimore · Washington D.C., District of Columbia and 1 other locations · NCT06624839

• Hub-Based Engagement Navigator to Reduce CSC Disengagement

  A hub-based Engagement Navigator Service will help people with early psychosis and their families stay engaged with Coordinated Specialty Care programs to see if this reduces treatment dropout.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland · NCT06583239

• Combining chemotherapy, immunotherapy, radiation, and heat treatment for advanced biliary tract cancer

  This study is testing a new combination of chemotherapy, immunotherapy, radiation, and heat treatment to see if it can help people with advanced biliary tract cancer who can’t have surgery.

  Recruiting at 2 sites Phase 1 University of Maryland, Baltimore · Baltimore, Maryland and 1 other locations · NCT06546969

• Integrated care for hospitalized patients with opioid and stimulant use disorders and infections

  This study tests if a new combined care approach for patients with infections from using opioids or stimulants can help them stay healthier and avoid going back to the hospital compared to regular treatment.

  Recruiting at 4 sites University of Maryland, Baltimore · Washington D.C., District of Columbia and 3 other locations · NCT06513156

• Peer support to improve HIV treatment adherence in high-risk populations

  This study is testing whether a peer support program can help Black individuals who use substances and are living with or at high risk for HIV stick to their long-acting injectable treatments better than standard care.

  Recruiting at 2 sites University of Maryland, Baltimore · Washington D.C., District of Columbia and 1 other locations · NCT06501781

• Effects of nutrient timing on cancer-related fatigue

  This study is testing if eating all meals within a 10-hour window can help cancer survivors with blood cancers feel less tired and improve their quality of life.

  Recruiting Phase 2 University of Maryland, Baltimore · Baltimore, Maryland · NCT06482515

• Wearable ankle robot to promote neuroplasticity after traumatic brain injury

  A wearable ankle rehabilitation robot is tested in adults with acute traumatic brain injury to help regain movement using guided, game-based and feedback-enabled training, even for those with little or no motor output.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland · NCT06465290

• Wearable in-bed robot to boost early leg and ankle recovery after stroke.

  This trial will test a wearable in-bed robot to help people with a recent unilateral stroke — including those with little or no leg movement — retrain ankle and lower-limb function using passive and active training.

  Recruiting at 3 sites Phase 1/2 University of Maryland, Baltimore · Baltimore, Maryland and 2 other locations · NCT06404268

• Personalized lab and home balance training to reduce fall risk in older adults

  This program will try individualized lab-based perturbation training plus home exercises to reduce falls in older adults who have fallen before or walk with instability.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland · NCT06396650

• Using MRI-guided focused ultrasound to treat hand dystonia

  This study is testing a new ultrasound treatment to see if it can help people with hand dystonia who haven't found relief from other therapies.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland · NCT06367608

• Using Virtual Reality to Manage Symptoms in Cancer Patients

  This study is testing whether a virtual reality program can help cancer patients feel better by reducing pain, fatigue, sleep problems, depression, and anxiety after their treatment.

  Recruiting at 2 sites University of Maryland, Baltimore · Baltimore, Maryland and 1 other locations · NCT06248216

• Using open-label placebo to improve sleep and pain in chronic pain patients

  This study is testing if a special type of placebo treatment can help people with chronic jaw pain sleep better and feel less pain.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland · NCT06225817

• Exploring virtual reality for managing chronic pain in TMD patients

  This study is testing if using virtual reality can help people with chronic pain from temporomandibular disorder feel better compared to a fake VR experience.

  Recruiting at 2 sites University of Maryland, Baltimore · Baltimore, Maryland and 1 other locations · NCT06214923

• Inducing labor in morbidly obese patients using Misoprostol

  This study is testing whether two different doses of Misoprostol can help morbidly obese women have a vaginal delivery instead of a cesarean section when inducing labor.

  Recruiting Early Phase 1 University of Maryland, Baltimore · Baltimore, Maryland · NCT06199154

• Using virtual reality to help manage pain in sickle cell disease patients

  This study is testing if using virtual reality can help adults with sickle cell disease feel less pain during painful episodes.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland · NCT06184126

• 1 Hz rTMS to boost motor-cortex inhibition in people with schizophrenia

  We will test whether 1 Hz rTMS applied to the motor cortex can increase brain inhibition in adults with schizophrenia.

  Recruiting University of Maryland, Baltimore · Catonsville, Maryland · NCT06155682

• Effects of Imdusiran on Chronic Hepatitis B

  This study is testing if a new drug called Imdusiran can improve treatment for adults with chronic hepatitis B who are already taking antiviral medication.

  Recruiting Phase 2 University of Maryland, Baltimore · Baltimore, Maryland · NCT06154278

• Using advanced MRI to study brain metabolism in traumatic brain injury

  This study is testing a new type of MRI to see how brain metabolism changes in people with traumatic brain injury compared to healthy individuals and those with a different brain condition.

  Recruiting Phase 1 University of Maryland, Baltimore · Baltimore, Maryland · NCT06103201

• New blood test to reduce radiation in HPV-related throat cancer treatment

  This study is testing a new blood test to see if it can help identify patients with HPV-related throat cancer who might not need radiation after surgery, aiming to reduce side effects while keeping survival rates high.

  Recruiting at 2 sites Phase 2 University of Maryland, Baltimore · Baltimore, Maryland and 4 other locations · NCT06088381

• Dietary intervention to reduce symptoms of long COVID

  This study is testing if a special diet can help adults aged 50 and older with long COVID feel less tired and improve their muscle strength.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland · NCT05977179

• Improving brain function through exercise and cognitive training for people with mild cognitive impairment

  This study is testing if a 12-week program that combines exercise and brain training can help improve thinking skills in adults aged 50-80 with mild cognitive impairment.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland · NCT05948930

• Improving pain management for older adults with dementia

  This study is testing a new way to help nursing home staff better manage pain for older adults with dementia to improve their quality of life.

  Recruiting Phase 2 University of Maryland, Baltimore · Baltimore, Maryland and 10 other locations · NCT05858996

• Evaluating the need for physical therapy clearance before same-day discharge after joint surgery

  This study is testing if patients can safely go home on the same day after joint surgery without needing a physical therapy check first.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland and 1 other locations · NCT05858086

• Zinc supplementation's effect on blood sugar levels in prediabetics

  This study is testing if taking zinc supplements can help lower blood sugar levels in people with prediabetes.

  Recruiting Phase 4 University of Maryland, Baltimore · Lancaster, Pennsylvania · NCT05835037

• Evaluating the effects of suvorexant on drug demand in people with opioid use disorder

  This study is testing if the sleep medication suvorexant can help people with opioid use disorder reduce their cravings for drugs.

  Recruiting Early Phase 1 University of Maryland, Baltimore · Baltimore, Maryland · NCT05829655

• Training physicians in anal cancer screening and treatment in Nigeria

  This study is testing two different training programs for doctors in Nigeria to see which one helps them better screen for and treat anal cancer within the context of HIV care.

  Recruiting University of Maryland, Baltimore · Abuja · NCT05817370

• Using low contrast CT for planning heart valve replacement

  This study is testing if using less contrast dye in special CT scans can help doctors plan heart valve replacement surgery while keeping patients safer and saving money.

  Recruiting Phase 4 University of Maryland, Baltimore · Baltimore, Maryland · NCT05758701

• Using blood flow imaging to assess glaucoma

  This study is testing whether new imaging tools can help doctors see differences in blood flow in the eyes of people with glaucoma compared to healthy individuals.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland · NCT05726058

• Using hyperpolarized 13C MRI to visualize cancer metabolism

  This study is testing a new type of MRI that uses special imaging to see how tumors use energy, helping doctors understand different types of cancer better.

  Recruiting Phase 1/2 University of Maryland, Baltimore · Baltimore, Maryland · NCT05697406

• Evaluating heart function changes in sepsis treatment

  This study is trying to see how treating sepsis affects heart function in patients by using ultrasound to measure how well the heart is pumping before and after treatment.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland · NCT05634733

• Comparing antibiotic cement bead pouches to negative pressure wound therapy for open tibia fractures

  This study tests whether using antibiotic cement bead pouches or negative pressure wound therapy helps people with severe open tibia fractures heal better and avoid complications after surgery.

  Recruiting at 29 sites Phase 3 University of Maryland, Baltimore · Chandler, Arizona and 34 other locations · NCT05615844

• Using buspirone to help with opioid withdrawal

  This study is testing if the medication buspirone can help people with opioid use disorder feel less withdrawal symptoms and cravings while they are tapering off opioids.

  Recruiting Phase 2 University of Maryland, Baltimore · Baltimore, Maryland · NCT05511909

• Evaluating daily dosing methods of methadone for pain and opioid use disorder

  This study is testing whether taking methadone once or twice a day can better help people with chronic pain and opioid use disorder who are already on methadone treatment.

  Recruiting Phase 2/3 University of Maryland, Baltimore · Baltimore, Maryland · NCT05459402

• Using Onvansertib to treat relapsed small cell lung cancer

  This study is testing a new drug called onvansertib to see if it can help people with relapsed small cell lung cancer who haven't had success with chemotherapy.

  Recruiting Phase 2 University of Maryland, Baltimore · Baltimore, Maryland and 1 other locations · NCT05450965

• Reducing suicide risk in people with psychosis by targeting emotion regulation

  This study is testing a new therapy aimed at helping people with psychosis manage their emotions better to reduce their risk of suicide.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland · NCT05440214

• Using blood conservation technique during heart surgery to assess kidney function

  This study is testing if a blood-saving technique during heart surgery can help improve kidney function in patients while also reducing the need for blood transfusions.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland · NCT05349292

• Comparing direct and indirect methods for screening family members at risk for genetic conditions

  This study is testing two ways to reach out to family members at risk for Long QT Syndrome and Familial Hypercholesterolemia to see which method helps them get screened better, while also offering free genetic testing and counseling.

  Recruiting University of Maryland, Baltimore · Lancaster, Pennsylvania · NCT05348564

• Comparing tendon repair options during reverse shoulder replacement

  This study tests whether repairing a specific shoulder tendon during reverse shoulder replacement can help patients move their arm better and reduce the chance of dislocation.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland · NCT05344898

• Understanding retinal blood flow in glaucoma patients

  This study is testing if measuring blood flow in the retina can help find early signs of glaucoma in patients so that better treatments can be developed.

  Recruiting at 4 sites Phase 4 University of Maryland, Baltimore · Baltimore, Maryland and 3 other locations · NCT05344274

• Improving treatment for prostate cancer with metastases at diagnosis

  This study is testing if adding a special type of radiation therapy to standard treatment helps men with newly diagnosed prostate cancer that has spread feel better and live longer.

  Recruiting at 10 sites Phase 2 University of Maryland, Baltimore · La Jolla, California and 9 other locations · NCT05223803

• Understanding how genetics affect response to GLP1R agonists in obesity and diabetes

  This study is testing how genetics affect the way overweight or obese people from the Old Order Amish community respond to the diabetes medication semaglutide.

  Recruiting Phase 1 University of Maryland, Baltimore · Lancaster, Pennsylvania · NCT05071898

• Evaluating opioid withdrawal symptoms during medication tapering

  This study is testing how different people experience withdrawal symptoms when they slowly reduce their opioid use under medical supervision to help improve treatment for opioid use disorder.

  Recruiting Phase 2 University of Maryland, Baltimore · Baltimore, Maryland · NCT05027919

• Identifying treatment targets and biomarkers for dry eye disease in cancer patients

  This study is trying to learn more about eye problems in cancer patients, especially those with a specific condition, by looking at their eyes over time and comparing them to healthy individuals.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland · NCT04946721

• HEPLISAV-B (TLR‑9 adjuvanted) vaccine for adults with chronic hepatitis B

  This trial will try giving two HEPLISAV-B vaccine shots to adults with chronic hepatitis B who are virally suppressed on antiviral therapy to see if the vaccine is safe and how it affects their immune cells.

  Recruiting Phase 1 University of Maryland, Baltimore · Baltimore, Maryland · NCT04843852

• Using advanced MRI to diagnose brain tumors

  This study is testing a new type of MRI to see if it can better identify brain tumors called infiltrating gliomas in patients who are about to have surgery.

  Recruiting Phase 1 University of Maryland, Baltimore · Baltimore, Maryland · NCT04772456

• Using laser therapy and radiation to treat newly diagnosed gliomas

  This study is testing a new treatment that combines laser therapy and radiation to see if it helps people with newly diagnosed brain tumors called gliomas.

  Recruiting at 5 sites University of Maryland, Baltimore · Baltimore, Maryland and 4 other locations · NCT04699773

• Hybrid robot and electrical stimulation for stroke rehabilitation

  This study is testing a new way to help stroke survivors recover by using a robot for stretching along with electrical stimulation to see if it improves their movement and muscle strength.

  Recruiting Phase 1/2 University of Maryland, Baltimore · Baltimore, Maryland · NCT04550728

• Rocklatan vs latanoprost for ocular blood flow in ocular hypertension and suspected glaucoma

  This study tests whether adding netarsudil to latanoprost improves episcleral venous blood flow more than latanoprost alone in adults with ocular hypertension or suspected glaucoma.

  Recruiting at 4 sites Phase 4 University of Maryland, Baltimore · Baltimore, Maryland and 3 other locations · NCT04401982

• Focused radiation treatment for early stage breast cancer

  This study is testing a new focused radiation treatment using the GammaPod machine for early stage breast cancer to see if it can effectively target tumors while protecting healthy tissue.

  Recruiting at 4 sites University of Maryland, Baltimore · Baltimore, Maryland and 3 other locations · NCT04234386

• Understanding recovery after brain hemorrhage

  This study looks at how different types of brain bleeding affect recovery and how treatments in the hospital can impact patient outcomes for people with serious brain injuries.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland · NCT04189471

• Treatment for patients with difficult-to-treat acute myeloid leukemia

  This study is testing a new combination of chemotherapy drugs to see if it can help adults with tough-to-treat acute myeloid leukemia that hasn't responded to previous treatments.

  Recruiting Phase 2 University of Maryland, Baltimore · Baltimore, Maryland · NCT04050280

• Vaccination with the typhoid oral vaccine Vivotif for blood donors

  This study is testing the typhoid oral vaccine Vivotif in blood donors to see how it helps protect against typhoid fever and understand the immune response over time.

  Recruiting Phase 4 University of Maryland, Baltimore · Baltimore, Maryland · NCT03971669

• Understanding immune responses to typhoid and cholera vaccines

  This study is testing how the typhoid and cholera vaccines affect the immune system and gut bacteria in people who are having endoscopies.

  Recruiting Phase 4 University of Maryland, Baltimore · Baltimore, Maryland · NCT03705585

• Registry for GammaPod and Quality of Life in Breast Cancer

  This study is testing how well the GammaPod treatment works for women with early-stage breast cancer who have had surgery, while also looking at how it affects their quality of life.

  Recruiting at 4 sites University of Maryland, Baltimore · Bel Air, Maryland and 3 other locations · NCT03562273

• Vasopressin and Observational Analgesia in Healthy Volunteers

  We are testing whether intranasal vasopressin changes how people’s pain is shaped by watching others experience pain while in an MRI scan.

  Recruiting Phase 1/2 University of Maryland, Baltimore · Baltimore, Maryland · NCT03446456

• Using electrical stimulation and high protein diet to aid recovery after brain hemorrhage

  This study is testing if using electrical stimulation and a high protein diet can help adults recover better after a brain hemorrhage compared to standard care.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland · NCT03201094

• Rehabilitation using a wearable robot for stroke recovery

  This study is testing if using a wearable robot for rehabilitation can help people who have had a stroke recover better and improve their movement and balance.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland · NCT02369770

• Evaluating upper limb recovery after stroke using robotic assistance

  This study is trying to see how robotic assistance can help stroke survivors improve their arm movement and strength during the first six months of recovery.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland · NCT02359812

• Robot-assisted rehabilitation for stroke recovery

  This study is testing whether using robots for therapy can help stroke patients recover better use of their arms and hands compared to traditional methods.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland · NCT02359253

• Registry for carotid artery stenting procedures

  This study is tracking carotid artery stenting procedures to see how well they work and keep patients safe, focusing on people with serious carotid artery problems.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland · NCT02240862

• Observational study on Polycystic Kidney Disease

  This study is trying to learn more about autosomal dominant polycystic kidney disease by gathering information from 350 adults to improve understanding of the disease and its effects on health.

  Recruiting University of Maryland, Baltimore · Baltimore, Maryland · NCT01873235

NIH-funded research (newest 40 of 812)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Resilient HIV Implementation for LGBTQ Youth in Africa and Beyond

  A program to help young people ages 15–24 who are at risk for or living with HIV, especially sexual and gender minority youths, access better HIV prevention and care through real-world health practice improvements.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11628851

• Algorithms to find HLA-E neoantigens for cancer immunotherapy

  Aims to develop computer methods to discover tumor-specific targets presented by HLA-E to guide new T cell therapies for cancer.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11618504

• NPRL2 loss and focal cortical dysplasia in epilepsy

  This grant investigates how losing NPRL2 in the brain contributes to focal cortical dysplasia and epilepsy in children.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11617796

• New way to make head and neck cancer treatments work better

  A research project at the University of Maryland Baltimore aims to improve treatment for advanced head and neck cancer, with a focus on making cisplatin and newer therapies work better while reducing kidney side effects.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11614788

• Genetics and function of inherited brain disorders that affect thinking and behavior

  Scientists are studying how genes and cellular helpers shape brain development and why certain kids have intellectual disabilities and adaptive-behavior challenges.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11594180

• Finding broadly protective antibodies against Crimean-Congo Hemorrhagic Fever

  Researchers will study blood from people who survived CCHF to find human antibodies that protect against multiple virus variants, with early tests in animal models to check their breadth.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11556149

• Protecting patients from infections, antibiotic resistance, and other adverse events

  A national effort aims to prevent infections and antibiotic resistance in patients by linking hospitals, clinics, and labs to share best practices and rapid responses.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11549943

• Neuroinflammation, Epigenetics, and Male Brain Development in Autism

  This grant explores how immune signals in the developing brain and male biology might influence autism risk, focusing on when and how the brain’s wiring is shaped.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11540184

• How early exposure to anesthesia may affect a child’s brain

  This grant studies how short or long exposure to anesthesia in early childhood could influence brain development and later neurologic function in kids.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11539346

• Impact of early malaria prevention on malaria risk at school entry

  This project looks at how early childhood malaria prevention strategies affect malaria risk by the time children start school in sub-Saharan Africa.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11538379

• Skeletal muscle signals linked to lung blood vessel changes in PH-HFpEF

  Researchers are studying how signals from tired skeletal muscle might drive blood vessel changes in a type of heart failure-related high blood pressure, with patients potentially benefiting from new therapies in the future.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11535841

• BSMART: A program to help people with HIV quit smoking

  A program in HIV care settings tests a proven plan to help people with HIV quit smoking, using quick counseling and a switch to quitting medications.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11535386

• BSMAT: Helping people with HIV quit smoking through routine support

  A HIV care program in Botswana aims to help people living with HIV quit smoking using a proven 5A brief intervention plus support medication.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11535385

• Integrated approach to preventing anal cancer in HIV+ MSM through screening and treatment of HSIL

  This project tests a streamlined plan to prevent anal cancer in people living with HIV by screening for HSIL and treating it at clinics serving MSM.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11535378

• Resilient HIV Implementation for LGBTQ Youth in Africa and Beyond

  A patient-facing program aims to strengthen how HIV prevention and care are delivered to sexually and gender minority youths aged 15–24 who are at risk for or living with HIV.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11529272

• Host and parasite factors shaping P. vivax invasion of red blood cells

  Researchers will study how human blood cells and the parasite itself interact in people with vivax malaria to uncover factors that influence infection.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11528294

• Detection assays for HIV broadly neutralizing antibodies in patient samples

  A research project to develop faster tests that detect HIV variants that resist antibody therapies in people living with HIV.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11518076

• What makes P. vivax hide and later relapse in the liver

  Researchers are looking at parasite and liver cell factors that let P. vivax form dormant liver stages (hypnozoites) that cause relapsing malaria, to help people at risk of P. vivax infections.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11502986

• KPTN Loss and Megalencephaly: mTOR Activation as Therapeutic Target

  This research aims to understand how KPTN mutations contribute to brain overgrowth and epilepsy, with the goal of identifying targeted treatments for affected individuals.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11496107

• Understanding how HIV exposure in early life affects children's development in Africa

  This grant follows children born to mothers with HIV or without HIV in Malawi to see how early HIV exposure may shape their thinking, learning, and school readiness as they grow.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11478605

• Resilient HIV Implementation for LGBTQ Youth in Africa and globally

  A nationally/internationally coordinated program helps young people aged 15-24 who are at risk of or living with HIV, especially sexual and gender minorities, access better prevention and care through digital health and partnerships.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11474430

• Resilient HIV Implementation for HIV prevention and care in young sexual and gender minority youth

  A nationally coordinated program works with teens and young adults who are at risk for or living with HIV to speed up real-world solutions that prevent HIV and improve care for these groups.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11474429

• Resilient HIV Implementation for HIV Prevention and Care in LGBTQ Youth in Africa and beyond

  A patient-friendly program aims to improve HIV prevention and care for sexual and gender minority youths ages 15–24 who are at risk or living with HIV.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11474428

• Resilient HIV Implementation Science for LGBTQ Youths Now

  A nationwide program helps improve HIV prevention and care for young sexual and gender minority people (ages 15–24) by testing practical ways to put proven strategies into real-world use.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11474427

• Resilient HIV Implementation Center for LGBTQ Youth in Africa and Beyond

  A patient-facing program to speed up how HIV prevention and care reach 15-24 year-old sexual and gender minority youth, especially in Africa, by studying real-world ways to put proven practices into everyday care.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11474426

• Regulation and role of pDCs in HBV/HIV coinfection immune problems

  This grant studies how a special type of immune cell called pDCs interacts with HIV and HBV in coinfected people to shape immune responses and liver disease.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11473256

• First-in-class cancer drug that blocks protein translation and an immune checkpoint

  A new type of cancer drug aims to hit two important cancer pathways at once to slow or stop tumor growth with potentially fewer side effects.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11473208

• Modeling and treating HIV-related lung infections

  A study at the University of Maryland Baltimore will explore how HIV affects lung immunity and how this leads to lung infections, with the goal of finding new ways to prevent and treat these infections in people living with HIV.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11470347

• Understanding the dormant liver form of vivax malaria

  Using advanced molecular profiling on parasites and liver cells to learn how P. vivax hides in the liver and later causes relapsing malaria in people at risk.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11467296

• Tracking genetic signs of artemisinin resistance in African malaria

  This project tracks genetic changes in malaria parasites in Africa to find early signs that artemisinin drugs may be becoming less effective for people with malaria.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11464820

• Understanding how cancers resist drugs that target ribosome production

  A cancer-focused project tests why certain cancers resist a new type of drug that blocks ribosome production, with scientists at the University of Maryland Baltimore looking for clues to improve therapy.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11457141

• Estrogen and Sleep: How Female Hormones Shape Sleep and Wakefulness

  This grant explores how estrogen affects sleep and wakefulness in adults, aiming to understand why sleep problems are more common in women.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11455495

• Integrated Services for PWID: person-centered care for HIV in Zambia

  A patient-focused project in Zambia will test a person-centered, integrated care approach to help people who inject drugs access HIV testing, linkage to care, and ongoing treatment.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11455236

• Rickettsia entry: how these bacteria invade human cells via arthropod vectors

  This grant studies how Rickettsia bacteria invade human cells, spread inside them, and interact with our immune system, with the goal of finding new ways to prevent and treat infections transmitted by ticks and other arthropods.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11454495

• New ways to fix biased brain and body age measurements from AI models

  A short project will improve AI-based aging clocks to give more reliable biological age estimates for people, including those at risk for Alzheimer’s disease.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11453261

• Plant-derived nanoparticles as a sepsis therapy (a potential new treatment approach)

  A new nanoparticle-based therapy derived from plants aims to calm the body's inflammatory response in sepsis, potentially improving survival for patients with severe infections.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11453246

• Comparing cigarettes and e-cigarettes for older adults with high blood pressure

  This study compares the effects of smoking vs. exclusive e-cigarette use on heart and blood vessel health in adults aged 50 and older with hypertension.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11453143

• Enhancer RNA CYP11A1-eRNA in castration-resistant prostate cancer

  Researchers are testing a new RNA-based target, CYP11A1-eRNA, to see if blocking it can hamper the growth of castration-resistant prostate cancer in the lab and animal models.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11452128

• Time-restricted eating for fatigue and frailty in people with cancer

  A 12-week study will test whether eating within a daily 10-hour window helps reduce fatigue and slow frailty in people living with advanced cancer.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11449363

• Non-invasive MR‑guided brain hyperthermia to boost brain cancer treatment

  A new MR‑compatible device heats brain tumors non‑invasively to help radiation, chemotherapy, and immunotherapy work better for brain cancer.

  NIH research University of Maryland Baltimore · Baltimore, United States · NIH-11448450

Quick answers

How many clinical trials run by University of Maryland Baltimore are recruiting right now?

93, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 3 countries. The most sites are in United States (92 trials), Nigeria (1 trial), Canada (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 16, Phase 4: 8, Phase 1: 7, Phase 1/2: 5. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

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