Using low contrast CT for planning heart valve replacement

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the use of low-dose iodinated contrast in dual energy CT scans for patients scheduled to undergo transcatheter aortic valve replacement (TAVR). The aim is to determine if this method can effectively assist in presurgical planning while reducing the risk of acute kidney injury and addressing the shortage of iodinated contrast agents. By utilizing monoenergetic reconstruction techniques, the study seeks to optimize imaging quality with a lower volume of contrast. This approach could lead to significant cost savings for healthcare facilities and improve patient safety.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* scheduled to receive TAVR abdominal CT

Exclusion Criteria:

* cannot undergo CT scan
* Allergy to intravenous contrast not controlled by steroids or benadryl
* GFR\<30

Where it's running

• University of Maryland Medical Center
  Baltimore, Maryland, United States Recruiting

Study contacts

• Study coordinator: Vikas Kundra, M.D., Ph.D
• Email: vkundra@som.umaryland.edu
• Phone: 410-328-3477

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• SYMmetric Valve expansion to reduce hypoattenuated leaflet thickening after balloon-expandable TAVI

  This trial tests whether the Double-TAP post-dilatation strategy can reduce HALT and improve valve function in patients 70 or older undergoing balloon-expandable TAVI.

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• Low-dose Colchicine after TAVR to help prevent valve clots

  This study tests whether taking a low dose of colchicine for 12 months after transcatheter aortic valve replacement can reduce valve thrombosis compared with standard care alone.

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• Transcatheter Mitral and Tricuspid Interventions and Cardiac MRI Registry

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  Recruiting Centro Cardiologico Monzino · Milan, Milan · NCT07370467

• Evaluation of the Point-Guard device during heart valve replacement

  This study is testing a new device called Point-Guard to see if it can help prevent brain problems during heart valve replacement surgery.

  Recruiting Transverse Medical, Inc. · Clayton, Victoria · NCT06962371

• Single versus Dual Perclose Device Closure for Large-Bore Femoral Access in TAVR

  This will test whether using one Perclose device instead of two closes large-bore femoral access faster and with similar or fewer complications in people having transfemoral TAVR.

  Recruiting Wake Forest University Health Sciences · Milwaukee, Wisconsin · NCT06871774

• Assessing coronary artery disease in patients undergoing TAVI

  This study is testing whether a non-invasive way to check for heart artery problems is better than the usual invasive method for patients with severe aortic stenosis who are getting a new heart valve.

  Recruiting Insel Gruppe AG, University Hospital Bern · Bern · NCT06559332

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.