Evaluating heart function changes in sepsis treatment
Evaluation of Mitral Annulus Systolic Plane Excursion (MAPSE) in Emergency Department Patients With Sepsis
University of Maryland, Baltimore · NCT05634733
This study is trying to see how treating sepsis affects heart function in patients by using ultrasound to measure how well the heart is pumping before and after treatment.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 50 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Maryland, Baltimore (other) |
| Locations | 1 site (Baltimore, Maryland) |
| Trial ID | NCT05634733 on ClinicalTrials.gov |
What this trial studies
This observational study focuses on patients diagnosed with sepsis or septic shock, aiming to assess changes in cardiac function during treatment. Using point-of-care ultrasound (POCUS), the study will measure the mitral annulus systolic plane excursion (MAPSE) to evaluate how well the heart is pumping before and after treatment. The goal is to understand the impact of sepsis on heart function and how treatment may improve it. The study will involve non-invasive ultrasound imaging performed in the emergency department setting.
Who should consider this trial
Good fit: Ideal candidates for this study are adults diagnosed with sepsis or septic shock.
Not a fit: Patients under 18 years old or those without a diagnosis of sepsis will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to improved understanding and management of cardiac dysfunction in sepsis patients, potentially enhancing treatment outcomes.
How similar studies have performed: Previous studies have indicated that ultrasound assessments can provide valuable insights into cardiac function in critically ill patients, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Diagnosis of Sepsis or Septic Shock Exclusion Criteria: * Age equal to or less than 17 * patient in the emergency department * Unable to perform POCUS exam due to medical necessity * Patients without sepsis * unable to obtain consent or have a legal representative consent
Where this trial is running
Baltimore, Maryland
- University of Maryland Medical Center — Baltimore, Maryland, United States (RECRUITING)
Study contacts
- Study coordinator: Alexis Salerno, MD
- Email: alexis.salerno@som.umaryland.edu
- Phone: (667) 214-2208
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Sepsis, POCUS, Emergency Department, echocardiography