BSMAT: Helping people with HIV quit smoking through routine support
Official title: Botswana Smoking Abstinence Reinforcement Trial (BSMART)
Funded at University of Maryland Baltimore · NIH-11535385 · Data updated 2026-11-12
A HIV care program in Botswana aims to help people living with HIV quit smoking using a proven 5A brief intervention plus support medication.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Maryland Baltimore NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | September 15, 2022 |
| Project end | August 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $47,271 |
| NIH project number | 3U01CA275048-05S1 |
| Project ID | NIH-11535385 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults living with HIV who smoke and receive care at participating HIV clinics.
✕Less likely to help
Individuals not interested in cessation or those outside the participating clinics may not benefit.
What this research studies
This project tests whether integrating a structured, lay-delivered SBIRT (Ask, Advise, Assess, Assist, and Arrange) with access to varenicline through HIV clinics can help people living with HIV in Botswana stop smoking and stay engaged in care. It uses a Type 2 hybrid design to measure both how well the intervention works and how easily clinics can adopt and maintain it in routine practice. Trained lay workers deliver the 5As, with nurse prescribers monitoring varenicline, to create a scalable, real-world approach to cancer prevention in HIV care. The study follows RE-AIM principles to evaluate reach, effectiveness, adoption, implementation quality, and maintenance, plus preliminary costs. Results could inform broader efforts to reduce smoking-related health risks in PLWH.
Why it matters
Potential benefit: If successful, this approach could reduce smoking-related health risks and improve overall health outcomes for people living with HIV.
How similar studies have gone: Previous research supports SBIRT and varenicline for smoking cessation, but this health-system–level implementation in HIV care is being tested in this context.
Where this research is happening
-
University of Maryland Baltimore
Baltimore, United States Active
Researchers
- Principal investigator: Charurat, Manhattan E — University of Maryland Baltimore
- Study coordinator: Charurat, Manhattan E
Related research
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Social stress and smoking: why disadvantaged young adults struggle to quit
This grant looks at how daily social stress affects if and when disadvantaged young adults who smoke can quit and stay quit.
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BSMART: A program to help people with HIV quit smoking
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I-STOP: a mobile health program to help people with HIV quit smoking
A smartphone-based program designed to help people with HIV quit smoking in a sustainable, affordable way.
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Smoking cessation help for people with HIV in South Africa
A program is being tested to help people living with HIV in South Africa quit smoking in ways that fit low-resource clinics and show good value.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.