RNA sequencing of removed tracheal tissue to characterize scarring in tracheal and subglottic stenosis

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational project collects tissue that would otherwise be discarded during routine biopsies or surgical resections in patients with benign tracheal or subglottic stenosis. Researchers will perform RNA sequencing to profile gene expression and define disease-specific molecular signatures. Patients with malignancy or active infection are excluded, and clinical care is not altered by participation. The aim is to map cellular and inflammatory pathways involved in fibroinflammatory airway narrowing to inform future diagnostics and therapies.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients with benign tracheal stenosis

Exclusion Criteria:

* Malignancy. active infection

Where it's running

• University of Maryland
  Baltimore, Maryland, United States Recruiting

Study contacts

• Study coordinator: Chenchen Zhang, MD
• Email: chenchen.zhang@som.umaryland.edu
• Phone: 14103288141

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Other studies for the same condition or treatment. Recruiting studies are listed first.

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.