Condition

Hemodialysis clinical trials and research

• 33Clinical trials
• 42NIH research projects
• 17Countries

Newest Hemodialysis clinical trials

All recruiting trials (33)

• Bioimpedance Spectroscopy for Fluid Changes in Hemodialysis Patients

  This study tests whether raw bioimpedance data can help doctors gauge fluid changes in people on hemodialysis and guides fluid removal decisions.

  Recruiting University of Aarhus · Aarhus, Central Denmark · NCT07803029

• Nurse-led dialysis self-management program for distress in adults on hemodialysis

  A nurse-led program helps adults on hemodialysis see if structured self-management support reduces dialysis-related distress compared to routine care.

  Recruiting Kutahya Health Sciences University · Simav · NCT07747012

• Repeated brief limb ischemia to see its effect on blood pressure and inflammation in people with kidney disease

  This study tests whether short, repeated episodes of limb ischemia can influence blood pressure, heart rate, and inflammation in adults with chronic kidney disease who may be on hemodialysis.

  Recruiting at 2 sites Medical University of Lodz · Lodz and 1 other locations · NCT07746102

• Mindfulness Meditation for Hemodialysis Patients

  A small trial tests whether a 4-week mindfulness meditation program in addition to usual care can improve sleep quality and reduce stress and symptoms in adults on hemodialysis.

  Recruiting at 4 sites Cyprus Aydin University · Famagusta and 3 other locations · NCT07620990

• Progressive muscle relaxation to ease depression and fatigue during hemodialysis

  This trial will try whether guided progressive muscle relaxation can reduce depression and fatigue in people receiving hemodialysis.

  Recruiting at 2 sites Istanbul Aydın University · Istanbul, Istanbul and 1 other locations · NCT07512895

• Multispecies synbiotic in people on hemodialysis

  This pilot study tests whether a multispecies synbiotic can alter gut microbes and reduce gut-derived toxins in adults on maintenance hemodialysis over 12 weeks.

  Recruiting Tungs' Taichung Metroharbour Hospital · Taichung, Wuqi District · NCT07461233

• When to give dialysis before surgery in kidney failure patients

  This study tests whether having same-day dialysis before non-emergency surgery is feasible and safe for people with end-stage kidney disease.

  Recruiting Stanford University · Stanford, California · NCT07339202

• My Voice — web-based advance care planning for people on dialysis

  This project will test whether the My Voice website helps people on dialysis and their caregivers have clearer advance care planning conversations and feel more prepared for future end-of-life care.

  Recruiting Duke-NUS Graduate Medical School · Singapore · NCT07309367

• Dialysis method comparison for people aged 85 and older

  This test will compare hemodiafiltration and high-flux hemodialysis to see which gives shorter recovery time and less fatigue for people aged 85 and older.

  Recruiting at 4 sites AUB Santé · Bretagne and 3 other locations · NCT07278973

• AV-001 to Prevent Brain Injury from Hemodialysis

  This study will test whether giving AV-001 before dialysis can protect the brains of adults on regular hemodialysis by strengthening blood vessels and reducing inflammation.

  Recruiting Phase 2 London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · London, Ontario · NCT07234890

• Changing magnesium and acid type in dialysis fluid to reduce clotting and immune activation

  This project tests whether changing the magnesium level and acid type in dialysis fluid can reduce immune-driven clotting and inflammation in people on maintenance hemodialysis.

  Recruiting Universitair Ziekenhuis Brussel · Brussels · NCT07206524

• Contactless optical monitoring of dialysis fistulas and grafts with the PatenSee system

  This study will test a contactless camera-based system (PatenSee) to monitor arteriovenous fistulas or grafts in adults who receive regular hemodialysis.

  Recruiting PatenSee Ltd. · Detroit, Michigan and 1 other locations · NCT07194395

• Uric acid clearance with routine hemodialysis in adults on maintenance dialysis

  This project tests whether routine hemodialysis alone removes enough uric acid in adults with end-stage kidney disease who dialyze two or three times per week.

  Recruiting Sohag University · Sohag · NCT07144332

• Hemoadsorption with the Jafron HA130 cartridge during hemodialysis for adults on maintenance dialysis with inflammation

  This trial will try adding Jafron HA130 hemoadsorption to regular hemodialysis to see if it reduces inflammation in adults on maintenance dialysis who have high CRP or IL-6.

  Recruiting Botkin Hospital · Moscow · NCT07123909

• Carotid ultrasound to predict blood pressure drops during dialysis

  We're testing whether carotid ultrasound measurements can help predict which adults on long-term hemodialysis will have drops in blood pressure during treatment.

  Recruiting First Affiliated Hospital of Wannan Medical College · Wuhu, Outside of the US · NCT07033260

• Pleth Variability Index to predict low blood pressure during maintenance hemodialysis

  This will test whether a simple pulse-oximeter reading (PVI) can help predict which adults on routine hemodialysis will develop low blood pressure so clinicians can act earlier.

  Recruiting First Affiliated Hospital of Wannan Medical College · Wuhu, Anhui · NCT07022847

• Personalised exercise support for people on hemodialysis.

  This project will test whether personalised coaching from an adapted physical activity teacher together with an advanced practice nurse helps adults who recently started hemodialysis become more active than standard nurse support.

  Recruiting Centre Hospitalier Departemental Vendee · La Roche-sur-Yon · NCT06981832

• Evaluating infection diagnosis in dialysis patients with sepsis

  This study is testing which method of taking blood samples works best to diagnose infections in dialysis patients who might have serious bloodstream infections.

  Recruiting Western Galilee Hospital-Nahariya · Nahariya, Israel · NCT06963853

• Comparing two methods to guide iron treatment in dialysis patients with anemia

  This study is testing whether using a new method to guide iron treatment can help adults with kidney disease and anemia feel better compared to the standard method.

  Recruiting King Chulalongkorn Memorial Hospital · Pathumwan, Bangkok · NCT06906835

• Personalized exercise program for patients on hemodialysis

  This study is testing whether a personalized exercise program can help people on hemodialysis feel better and improve their quality of life compared to a standard exercise plan.

  Recruiting University of Arizona · Tucson, Arizona · NCT06830993

• Exercise before dialysis to protect heart function

  This study is testing if doing cycling exercises before dialysis can help protect the heart and improve symptoms for people undergoing hemodialysis.

  Recruiting London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · London, Ontario · NCT06735378

• Manuka honey mouth rinse for people on hemodialysis with periodontitis

  This tests whether a Manuka honey mouth rinse can improve gum disease in adults with end-stage kidney disease who are receiving hemodialysis.

  Recruiting Phase 3 Ain Shams University · Banhā · NCT06726876

• Investigating the impact of fear of movement on pain and quality of life in hemodialysis patients

  This study is trying to see how fear of movement affects pain and quality of life in people who have been on hemodialysis for kidney disease.

  Recruiting Kirsehir Ahi Evran Universitesi · Kırşehir · NCT06696274

• Using special dialysis membranes to reduce itching in kidney patients

  This study is testing if special dialysis membranes can help reduce itching in patients with advanced kidney disease who are on hemodialysis.

  Recruiting Saint Petersburg State University, Russia · Saint Petersburg · NCT06671535

• Investigating the link between FGF23 and heart rhythm issues in dialysis patients

  This study is trying to see if levels of a protein called FGF23 are linked to heart rhythm problems in patients who are on dialysis.

  Recruiting Ente Ospedaliero Cantonale, Bellinzona · Lugano · NCT06668831

• Dialysis that removes more middle molecules using super high‑flux filters

  This trial will test whether using super high‑flux (expanded) dialysis filters instead of standard high‑flux filters reduces the risk of death and other harms for adults on in‑center hemodialysis who are older or have diabetes.

  Recruiting at 2 sites London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's · London, Ontario and 2 other locations · NCT06660277

• Effect of Second Level Reiki on Pain and Quality of Life in Hemodialysis Patients

  This study is testing if 20-minute Reiki sessions over four days can help reduce pain and improve the quality of life for people on hemodialysis.

  Recruiting Mersin University · Çorum · NCT06519136

• Effects of royal jelly on inflammation in chronic kidney disease patients

  This study is testing if taking royal jelly can help reduce inflammation in people with chronic kidney disease who are on hemodialysis.

  Recruiting Universidade Federal Fluminense · Rio de Janeiro, Rio de Janeiro · NCT06438445

• Vitamin D3 supplementation for chronic pain relief in hemodialysis patients

  This study is testing if high doses of vitamin D3 can help reduce chronic pain in patients on hemodialysis.

  Recruiting Taipei Medical University Hospital · Taipei · NCT05667090

• Preventing infections in hemodialysis patients with antibiotics

  This study is testing if giving antibiotics to people starting hemodialysis can help prevent serious infections during their treatment.

  Recruiting at 4 sites Zealand University Hospital · Copenhagen, Capital Region and 6 other locations · NCT05248620

• Factors affecting brain health in hemodialysis patients

  This study looks at how different factors affect brain health in people aged 50 to 85 who have been on hemodialysis for over three months.

  Recruiting Huashan Hospital · Shanghai, Shanghai Municipality · NCT04433455

• Thyroid hormone supplementation for patients on hemodialysis

  This study is testing if a thyroid hormone pill can help people on hemodialysis with mild thyroid issues feel better and improve their heart health.

  Recruiting University of California, Irvine · Orange, California · NCT03977207

• Alirocumab for people on stable dialysis

  This study tests whether alirocumab can safely lower cholesterol in adults on stable hemodialysis or peritoneal dialysis over 12 weeks.

  Recruiting Phase 3 Baylor Research Institute · Dallas, Texas · NCT03480568

NIH-funded research (newest 40 of 42)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Optimizing a prehabilitation program for kidney transplant candidates on dialysis

  A program to improve physical function and readiness for kidney transplant in people on dialysis is being developed and tested to help candidates stay healthier while they wait.

  NIH research New York University School of Medicine · New York, United States · NIH-11421433

• Simulator-based training to improve dialysis needle skills for patients with kidney failure

  A new simulator-based curriculum will train dialysis care providers to position and insert needles more safely and consistently for people with end-stage kidney disease.

  NIH research Sojourn Medtech LLC · Pendleton, United States · NIH-11409703

• Implanted dialysis device for safe, easy at-home hemodialysis

  A new implanted dialysis cartridge and at-home system aim to let people with kidney failure dialyze themselves more safely and conveniently at home.

  NIH research Silicon Kidney, LLC · San Ramon, United States · NIH-11408209

• Improving how patients choose their hemodialysis access

  A patient-friendly project to help people with kidney failure better understand and decide between AV fistula, graft, or catheter for hemodialysis.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-11400532

• IVUS in AV access dysfunction for hemodialysis patients

  A new approach tests whether using intravascular ultrasound (IVUS) in people with failing AV fistulas or grafts improves diagnosis and guides treatment to prevent more blockages.

  NIH research Boston Medical Center · Boston, United States · NIH-11378544

• StepNet-Adapt: a personalized mobile program to boost activity for people on dialysis

  A personalized mobile health program uses wearables, texts, and coaching to help people on hemodialysis become more physically active.

  NIH research University of California, San Diego · La Jolla, United States · NIH-11345269

• Cardiovascular health with different dialysis strategies in twice- vs thrice-weekly treatment

  This study compares two ways of starting dialysis to see how heart and vessel health and outcomes differ for people beginning dialysis.

  NIH research Wake Forest University Health Sciences · Winston-Salem, United States · NIH-11343747

• Hypoxia's role in vein changes after kidney-disease-related dialysis grafts

  This project looks at how low oxygen levels affect vein changes that can block arteriovenous fistulas used for hemodialysis.

  NIH research Mayo Clinic Rochester · Rochester, United States · NIH-11330335

• Biodegradable vascular scaffolds to improve dialysis access health

  A new biodegradable scaffold is being studied to improve how arteriovenous fistulas and grafts function for people needing dialysis.

  NIH research W G Hefner VA Medical Center · Salisbury, United States · NIH-11264881

• A device to improve safety and efficiency in hemodialysis treatments

  This study is testing a new implantable device that helps make it easier and safer for patients on hemodialysis to get their needles in the right spot, which could lower the chances of infections and other problems during treatment.

  NIH research Flowpoint Medical INC · Overland Park, United States · NIH-11237368

• Intradialytic Heart Stress in Dialysis Patients

  A study in people on hemodialysis to understand why their heart sometimes gets stressed during treatment and how this might raise the risk of heart problems.

  NIH research New York University School of Medicine · New York, United States · NIH-11229583

• Gradual dialysis schedules for Veterans new to dialysis

  This trial compares starting dialysis twice-weekly versus the usual three-times-weekly schedule for Veterans beginning dialysis to see if the gentler approach improves quality of life, preserves remaining kidney function, and reduces treatment burdens.

  NIH research Veterans Health Administration · Long Beach, United States · NIH-11212769

• Improving Hemodialysis Access Care with Ultrasound

  This project explores how a special ultrasound technique can help doctors better understand and treat problems with hemodialysis access for people with kidney disease.

  NIH research Boston Medical Center · Boston, United States · NIH-11190925

• Fistula versus graft for hemodialysis access in older adults

  This study compares two types of surgical dialysis access—fistulas and grafts—to find which is better for adults aged 65 and older who are using a catheter for hemodialysis.

  NIH research Wake Forest University Health Sciences · Winston-Salem, United States · NIH-11178427

• Making hemodialysis blood-access decisions easier

  This project will build an easy-to-use, evidence-based guide to help people on or approaching hemodialysis and their doctors choose the best type of vascular access for their situation.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-11167797

• Improving transportation solutions for patients needing dialysis

  This study is looking for ways to help people with end-stage kidney disease get to their hemodialysis appointments more easily, so they don’t miss treatments that are crucial for their health.

  NIH research University of California at Davis · Davis, United States · NIH-11143927

• Blood pressure–guided fluid removal during hemodialysis

  This project uses blood pressure patterns recorded during dialysis to guide how much fluid is removed for people on hemodialysis.

  NIH research VA North Texas Health Care System · Dallas, United States · NIH-11132726

• Slippery coating for dialysis catheters to prevent clots and infection

  A non-stick liquid-like coating for dialysis catheters designed to help people on hemodialysis avoid blood clots and bloodstream infections.

  NIH research Cerulean Scientific INC. · Lancaster, United States · NIH-11126044

• Managing blood pressure at home for patients on hemodialysis

  This study is looking at whether checking your blood pressure at home can help people on hemodialysis stay healthier compared to just measuring it at the clinic before treatments.

  NIH research University of Washington · Seattle, United States · NIH-11121842

• Understanding how fluid removal affects blood flow during dialysis for kidney injury

  This study is looking at how removing fluid during dialysis affects blood flow in people with acute kidney injury, and it aims to find better ways to keep track of fluid levels to help prevent problems like too much fluid or low blood pressure, ultimately making dialysis safer and more tailored to each patient's needs.

  NIH research University of Pennsylvania · Philadelphia, United States · NIH-11088708

• Understanding Infections in Hospitalized Dialysis Patients

  This project looks at infections that people on kidney dialysis get while in the hospital, especially focusing on how often they happen and who is most affected.

  NIH research Rhode Island Hospital · Providence, United States · NIH-11086831

• Using blood pressure patterns to improve fluid management in dialysis patients

  This study is looking at how keeping an eye on blood pressure during dialysis can help doctors safely remove extra fluid from patients with severe kidney disease, especially veterans, to make their treatment safer and improve their health.

  NIH research VA North Texas Health Care System · Dallas, United States · NIH-11056677

• A device to improve needle insertion for hemodialysis

  This study is testing a new device that helps make needle insertions safer and more accurate for people getting hemodialysis, so they can have a better experience and reduce the risk of complications.

  NIH research Flowpoint Medical INC · Overland Park, United States · NIH-11013179

• Improving vascular access for patients on hemodialysis

  This study is working on a new way to help people who need hemodialysis by creating special biodegradable materials that make it easier and safer to connect blood vessels, aiming to improve their treatment experience.

  NIH research W G Hefner VA Medical Center · Salisbury, United States · NIH-11007158

• Improving predictions of health risks for patients on hemodialysis

  This study is looking to improve how we predict health issues for people on hemodialysis by considering important social factors, like access to healthcare and personal circumstances, to help doctors provide better care.

  NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-10991307

• Using at-home neurostimulation to reduce pain in patients with end-stage kidney disease on dialysis

  This study is looking at a new way to help people with end-stage kidney disease manage their pain at home during hemodialysis using a gentle electrical stimulation method, which could reduce the need for strong pain medications.

  NIH research Weill Medical Coll of Cornell Univ · New York, United States · NIH-10991001

• Investigating heart issues during dialysis in patients

  This study is looking into a heart issue called intradialytic myocardial stunning that affects people on hemodialysis, with the goal of finding out how it leads to heart problems and discovering new ways to help improve their health.

  NIH research New York University School of Medicine · New York, United States · NIH-10980520

• Gradual hemodialysis treatment for veterans starting dialysis

  This study is looking at a new way to do hemodialysis for veterans with end-stage kidney disease by starting with fewer sessions each week, so patients can ease into treatment and hopefully feel better overall.

  NIH research Veterans Health Administration · Long Beach, United States · NIH-10975934

• Using ultrasound to improve access for kidney dialysis patients

  This study is looking at how using a special ultrasound tool can help doctors better diagnose and treat problems with the blood vessels used for hemodialysis in patients with kidney disease, making sure they get the best care possible.

  NIH research Boston Medical Center · Boston, United States · NIH-10946295

• Investigating infections in patients on hemodialysis during hospital stays

  This study is looking at how common infections are for people on hemodialysis and what factors, like race and living conditions, might increase their risk, so we can find better ways to keep them healthy and safe in the hospital.

  NIH research Rhode Island Hospital · Providence, United States · NIH-10925332

• Improving decision-making for vascular access in hemodialysis patients

  This study is working to make it easier for people with end-stage kidney disease who need hemodialysis to choose the best type of access for their treatment by creating a helpful guide that shows the possible outcomes of different options.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-10913417

• Comparing two types of vascular access for older adults on hemodialysis

  This study is looking at how well two types of surgeries for getting blood access work for older adults with severe kidney disease who need dialysis, to see which one helps them feel better and be happier with their treatment.

  NIH research Wake Forest University Health Sciences · Winston-Salem, United States · NIH-10912828

• A new coating for hemodialysis catheters to prevent infections and improve function

  This study is testing a new coating for hemodialysis catheters that helps prevent infections and improve how well they work, and it's for patients who are undergoing hemodialysis.

  NIH research Cerulean Scientific INC. · Lancaster, United States · NIH-10894142

• A new wearable device for continuous dialysis treatment

  This study is testing a new, smaller wearable dialysis device that uses super-thin membranes to help people with End Stage Renal Disease clean their blood more effectively, giving them the freedom to manage their treatment in a way that fits better into their daily lives.

  NIH research University of Rochester · Rochester, United States · NIH-10874664

• Understanding heart disease risk in patients on hemodialysis

  This study is looking at why people with severe kidney disease who are on dialysis often have heart problems, and it will check blood samples to find out which proteins might be linked to heart health, with the goal of creating better ways to prevent and treat heart disease for these patients.

  NIH research Ut Southwestern Medical Center · Dallas, United States · NIH-10836013

• A simulator to improve skills for hemodialysis cannulation

  This study is creating a smart training tool to help healthcare workers learn how to safely insert needles for hemodialysis, which is really important for patients with kidney failure, so they can do it better and reduce any risks for patients.

  NIH research Sojourn Medtech LLC · Pendleton, United States · NIH-10830667

• The link between gut bacteria and early death in dialysis patients

  This study is looking at how certain germs in the blood might affect inflammation and the risk of early death in people on hemodialysis, helping us understand their impact on heart health and overall well-being.

  NIH research University of Tennessee Health Sci Ctr · Memphis, United States · NIH-10793526

• Testing a new treatment to improve heart health in patients starting hemodialysis

  This study is looking at whether a combination of two heart medications, sacubitril and valsartan, can help improve heart health and protect kidney function in people who are just starting hemodialysis for advanced kidney failure.

  NIH research Brigham and Women's Hospital · Boston, United States · NIH-10771276

• How kidney issues affect hand function in dialysis patients

  This study is looking at how kidney problems might cause hand issues in people on dialysis, and it hopes to find ways to prevent or improve these hand problems by understanding the changes happening in the body during treatment.

  NIH research University of Florida · Gainesville, United States · NIH-10694865

• Using virtual reality to help hemodialysis patients with depression

  This study is testing a new virtual reality program that helps hemodialysis patients relax and feel better emotionally through guided meditation, aiming to improve their mental health and overall well-being.

  NIH research University of Illinois at Urbana-Champaign · Champaign, United States · NIH-10676316

Related topics

Quick answers

How many Hemodialysis clinical trials are recruiting right now?

33, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 17 countries. The most sites are in United States (5 trials), Turkey (Türkiye) (4 trials), Canada (3 trials), China (3 trials), France (2 trials). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 3: 2, Phase 2: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

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