Repeated brief limb ischemia to see its effect on blood pressure and inflammation in people with kidney disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The trial investigates the effects of four 5-minute cycles of limb ischemia, induced by cuff inflation, on hemodynamic and inflammatory laboratory parameters in adults with chronic kidney disease. Participants are hospitalized and undergo basic vitals monitoring and blood tests before and after the ischemic episodes. The study aims to identify any short-term changes in blood pressure, heart rate, and inflammation markers associated with repeated ischemic preconditioning. Data collection occurs over a 4-day hospitalization in the nephrology department. The design centers on a controlled ischemic intervention with standard clinical measurements.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* obtaining the patient's voluntary, informed consent to participate in the experiment,
* chronic kidney disease in stages G1-G5,
* women and men over 18 years of age.
* failure to meet the qualification criteria for participation in the study,
* consciousness disorders,
* heart failure (NYHA IV),
* severe anemia (Hb concentration\<8g/dL),
* features of muscle cell damage (e.g. rhabdomyolysis),
* peripheral circulation disorders, peripheral vascular diseases.

Exclusion Criteria:

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Where it's running

• Medical University of Lodzi
  Lodz, Poland Recruiting
• Medical University of Lodzi
  Lodz, Poland Recruiting

Study contacts

• Study coordinator: Michał Nowicki, Professor
• Email: nefro@wp.pl
• Phone: +48 42 201 44 00

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.