Understanding how fluid removal affects blood flow during dialysis for kidney injury
Macrovascular and Microvascular Response to Fluid Removal during Hemodialysis for Acute Kidney Injury
['FUNDING_OTHER'] · UNIVERSITY OF PENNSYLVANIA · NIH-11088708
This study is looking at how removing fluid during dialysis affects blood flow in people with acute kidney injury, and it aims to find better ways to keep track of fluid levels to help prevent problems like too much fluid or low blood pressure, ultimately making dialysis safer and more tailored to each patient's needs.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF PENNSYLVANIA (nih funded) |
| Locations | 1 site (PHILADELPHIA, UNITED STATES) |
| Trial ID | NIH-11088708 on ClinicalTrials.gov |
What this research studies
This research investigates the effects of fluid removal during hemodialysis on blood flow in patients with acute kidney injury (AKI). It aims to find better ways to monitor and manage fluid levels to prevent complications like fluid overload or low blood pressure. The study will use advanced technologies to continuously track blood flow and tissue perfusion during dialysis treatments, which could lead to more personalized care for patients. By identifying individual responses to fluid removal, the research seeks to improve patient outcomes during dialysis.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with acute kidney injury who require hemodialysis.
Not a fit: Patients with chronic kidney disease who are not currently experiencing acute kidney injury may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to safer and more effective dialysis treatments for patients with acute kidney injury.
How similar studies have performed: Previous research has shown promise in using continuous monitoring techniques during dialysis, but this specific approach is relatively novel.
Where this research is happening
PHILADELPHIA, UNITED STATES
- UNIVERSITY OF PENNSYLVANIA — PHILADELPHIA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BROTMAN, CHRISTINA HAO WANG — UNIVERSITY OF PENNSYLVANIA
- Study coordinator: BROTMAN, CHRISTINA HAO WANG
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: acute kidney injury