Clinical trial Recruiting at 1 site Observational Ages 18 and up

Uric acid clearance with routine hemodialysis in adults on maintenance dialysis

Official title: Assessment of the Efficacy of Hemodialysis on Uric Acid Clearance at End Stage Kidney Disease in Sohag University Hospital

Run by Sohag University · NCT07144332 · Data updated 2026-11-12

This project tests whether routine hemodialysis alone removes enough uric acid in adults with end-stage kidney disease who dialyze two or three times per week.

More Hemodialysis trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment100 (estimated)
SponsorSohag University
Academic / other
Locations1 site (Sohag)
StatusRecruiting
StartedJuly 13, 2025
Main results expectedDecember 29, 2025
Study endsFebruary 1, 2026
Registry record updatedAugust 27, 2025
Trial IDNCT07144332 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Adults aged 18 or older who have been on maintenance hemodialysis for at least three consecutive months, receive two to three sessions weekly of at least four hours, and are not taking uric-acid–lowering therapy.

Probably not a fit

Patients already on uric-acid–lowering medications, those on dialysis for under three months, those receiving emergency or shorter-than-four-hour sessions, and people on non-hemodialysis renal replacement therapies are unlikely to benefit from the findings.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This prospective cross-sectional study will enroll 100 consenting adults on maintenance hemodialysis at Sohag University Hospital over six months. Investigators will collect demographic and dialysis-related data and measure serum uric acid immediately before and after routine dialysis sessions to calculate uric acid clearance. Clearance between 65% and 80% is defined as low efficacy and above 80% as good efficacy. Patients on uric-acid–lowering drugs, those dialyzing less than four hours, who have been on dialysis for under three months, or who receive emergency dialysis sessions are excluded.

Why it matters

Potential benefit: If routine hemodialysis alone clears uric acid effectively, some patients may be able to avoid additional uric-acid–lowering medications.

How similar studies have gone: Previous studies show hemodialysis reduces serum uric acid but reported clearance rates vary widely, so reliance on dialysis alone to control hyperuricemia remains uncertain.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* We included all consenting adults aged 18 or older, on maintenance hemodialysis for at least 3 consecutive months receiving 2 to 3 sessions weekly

Exclusion Criteria:

1. Patients aged \< 18 years old .
2. Patients on recent hemodialysis less than 3 months.
3. We excluded patients who were on Uric acid lowering therapy (UALT).
4. Patients received less than 4 hours of hemodialysis and those who had emergency dialysis.

Where it's running

  • Sohag university faculty of medicine
    Sohag, Egypt
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.