NIH-funded research NIH-funded research

Biodegradable vascular scaffolds to improve dialysis access health

Official title: Hemodynamics, Uremia, Vascular Biology and Bioengineering: Creating the Ideal Hemodialysis Vascular Access

Funded at W G Hefner VA Medical Center · NIH-11264881 · Data updated 2026-11-12

A new biodegradable scaffold is being studied to improve how arteriovenous fistulas and grafts function for people needing dialysis.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionW G Hefner VA Medical Center
NIH-funded
Lab location1 site (Salisbury, United States)
Project startJanuary 1, 2024
Project endDecember 31, 2027
Funding year2026
NIH project number5I01BX006169-03
Project IDNIH-11264881 on NIH RePORTER

Who could benefit from this research

Could help

Patients with arteriovenous fistulas or grafts who may need improved vascular access options in the future.

Less likely to help

People without current or planned dialysis access issues may not benefit from this study.

What this research studies

This project aims to reduce problems with dialysis access by using a custom biodegradable scaffold placed in vessels to guide healing and better match arterial and venous properties. Researchers will explore how changing the scaffold material and fiber orientation affects blood flow, tissue integration, and the ease of early catheter removal. The work involves tests on biomaterials and animal models to understand safety and effectiveness before any human trials. If successful, this approach could lower intervention rates and improve long-term access for dialysis patients.

Why it matters

Potential benefit: If successful, patients could experience fewer interventions and better, longer-lasting dialysis access.

How similar studies have gone: Previous work shows promise with biodegradable scaffolds, but this specific approach is novel and exploratory.

Where this research is happening

  • W G Hefner VA Medical Center
    Salisbury, United States
    Active

Researchers

  • Principal investigator: Roy-Chaudhury, Prabir — W G Hefner VA Medical Center
  • Study coordinator: Roy-Chaudhury, Prabir

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.