Biodegradable vascular scaffolds to improve dialysis access health
Official title: Hemodynamics, Uremia, Vascular Biology and Bioengineering: Creating the Ideal Hemodialysis Vascular Access
Funded at W G Hefner VA Medical Center · NIH-11264881 · Data updated 2026-11-12
A new biodegradable scaffold is being studied to improve how arteriovenous fistulas and grafts function for people needing dialysis.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | W G Hefner VA Medical Center NIH-funded |
| Lab location | 1 site (Salisbury, United States) |
| Project start | January 1, 2024 |
| Project end | December 31, 2027 |
| Funding year | 2026 |
| NIH project number | 5I01BX006169-03 |
| Project ID | NIH-11264881 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients with arteriovenous fistulas or grafts who may need improved vascular access options in the future.
✕Less likely to help
People without current or planned dialysis access issues may not benefit from this study.
What this research studies
This project aims to reduce problems with dialysis access by using a custom biodegradable scaffold placed in vessels to guide healing and better match arterial and venous properties. Researchers will explore how changing the scaffold material and fiber orientation affects blood flow, tissue integration, and the ease of early catheter removal. The work involves tests on biomaterials and animal models to understand safety and effectiveness before any human trials. If successful, this approach could lower intervention rates and improve long-term access for dialysis patients.
Why it matters
Potential benefit: If successful, patients could experience fewer interventions and better, longer-lasting dialysis access.
How similar studies have gone: Previous work shows promise with biodegradable scaffolds, but this specific approach is novel and exploratory.
Where this research is happening
-
W G Hefner VA Medical Center
Salisbury, United States Active
Researchers
- Principal investigator: Roy-Chaudhury, Prabir — W G Hefner VA Medical Center
- Study coordinator: Roy-Chaudhury, Prabir
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.