Using blood pressure patterns to improve fluid management in dialysis patients

Using Intradialytic Blood Pressure Slopes to Guide Ultrafiltration in Hemodialysis Patients

['FUNDING_OTHER'] · VA NORTH TEXAS HEALTH CARE SYSTEM · NIH-11056677

This study is looking at how keeping an eye on blood pressure during dialysis can help doctors safely remove extra fluid from patients with severe kidney disease, especially veterans, to make their treatment safer and improve their health.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorVA NORTH TEXAS HEALTH CARE SYSTEM (nih funded)
Locations1 site (DALLAS, UNITED STATES)
Trial IDNIH-11056677 on ClinicalTrials.gov

What this research studies

This research investigates how monitoring blood pressure changes during dialysis can help guide fluid removal in patients with end-stage renal disease (ESRD). The study aims to develop a personalized approach to fluid management that minimizes complications like low blood pressure while effectively reducing excess fluid. By utilizing a novel algorithm, the research seeks to improve patient outcomes and reduce the high mortality rates associated with cardiovascular issues in veterans undergoing hemodialysis. The ultimate goal is to implement this approach in a larger clinical trial to validate its effectiveness.

Who could benefit from this research

Good fit: Ideal candidates for this research are veterans with end-stage renal disease who are undergoing maintenance hemodialysis.

Not a fit: Patients who are not veterans or those who are not on hemodialysis may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved fluid management strategies that significantly reduce mortality and hospitalization rates for dialysis patients.

How similar studies have performed: Previous research has shown promise in using blood pressure monitoring for fluid management in dialysis, suggesting that this approach could be effective.

Where this research is happening

DALLAS, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.