Using blood pressure patterns to improve fluid management in dialysis patients
Official title: Using Intradialytic Blood Pressure Slopes to Guide Ultrafiltration in Hemodialysis Patients
Funded at VA North Texas Health Care System · NIH-11056677 · Data updated 2026-11-12
This study is looking at how keeping an eye on blood pressure during dialysis can help doctors safely remove extra fluid from patients with severe kidney disease, especially veterans, to make their treatment safer and improve their health.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | VA North Texas Health Care System NIH-funded |
| Lab location | 1 site (Dallas, United States) |
| Project start | July 1, 2020 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| NIH project number | 5I01CX002009-05 |
| Project ID | NIH-11056677 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are veterans with end-stage renal disease who are undergoing maintenance hemodialysis.
✕Less likely to help
Patients who are not veterans or those who are not on hemodialysis may not benefit from this research.
What this research studies
This research investigates how monitoring blood pressure changes during dialysis can help guide fluid removal in patients with end-stage renal disease (ESRD). The study aims to develop a personalized approach to fluid management that minimizes complications like low blood pressure while effectively reducing excess fluid. By utilizing a novel algorithm, the research seeks to improve patient outcomes and reduce the high mortality rates associated with cardiovascular issues in veterans undergoing hemodialysis. The ultimate goal is to implement this approach in a larger clinical trial to validate its effectiveness.
Why it matters
Potential benefit: If successful, this research could lead to improved fluid management strategies that significantly reduce mortality and hospitalization rates for dialysis patients.
How similar studies have gone: Previous research has shown promise in using blood pressure monitoring for fluid management in dialysis, suggesting that this approach could be effective.
Where this research is happening
-
VA North Texas Health Care System
Dallas, United States Active
Researchers
- Principal investigator: Van Buren, Peter Noel — VA North Texas Health Care System
- Study coordinator: Van Buren, Peter Noel
Related research
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-
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.