Effects of royal jelly on inflammation in chronic kidney disease patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the impact of royal jelly supplementation on inflammation and cellular senescence in patients with chronic kidney disease (CKD) undergoing hemodialysis. Participants will receive either royal jelly or a placebo for 8 weeks, followed by a washout period and crossover to the alternate treatment. The study aims to assess changes in mRNA expression of key transcription factors and inflammatory markers through biological sample collection. This approach seeks to explore the potential benefits of royal jelly's bioactive compounds in mitigating complications associated with CKD.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* patients with CKD undergoing hemodialysis for more than 6 months
* patients with arteriovenous fistula (AVF) as vascular access.

Exclusion Criteria:

* pregnant,
* lactating,
* smoker
* patients using antibiotics and antioxidant supplements in the last three months
* patients with autoimmune and infectious diseases,
* patients with cancer, liver disease, and AIDS

Where it's running

• Denise Mafra
  Rio de Janeiro, Rio de Janeiro, Brazil Recruiting

Study contacts

• Study coordinator: Denise Mafra
• Email: dmafra30@gmail.com
• Phone: 21985683003

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.