NIH-funded research R01 grant

Making hemodialysis blood-access decisions easier

Official title: Improving the patient experience of hemodialysis vascular access decision making

Funded at University of California Los Angeles · NIH-11167797 · Data updated 2026-11-12

This project will build an easy-to-use, evidence-based guide to help people on or approaching hemodialysis and their doctors choose the best type of vascular access for their situation.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California Los Angeles
NIH-funded
Lab location1 site (Los Angeles, United States)
Project startSeptember 1, 2022
Project endAugust 31, 2027
Funding year2025
Award (this year)$423,035
NIH project number5R01DK129810-04
Project IDNIH-11167797 on NIH RePORTER

Who could benefit from this research

Could help

Adults with end-stage kidney disease who are on or approaching hemodialysis and facing a choice about an arteriovenous fistula, graft, or central venous catheter are the ideal candidates for the guide's use.

Less likely to help

People who do not need hemodialysis, pediatric patients, or those whose vascular access choice is already finalized may not directly benefit from this project.

What this research studies

If you need hemodialysis, choosing between a fistula, graft, or catheter can be confusing; researchers will link large national registries and Medicare data to see real-world outcomes of different access types. They will create prediction models using traditional statistics and machine-learning methods (for example, Bayesian networks and random forests) to estimate outcomes that matter to patients, like repeat surgeries or the need for revisions. From those models they will build an interactive guide that presents likely short- and long-term outcomes in plain language. The team will also identify how clinicians can use the guide during visits so you can make clearer, more personalized decisions with your care team.

Why it matters

Potential benefit: If successful, this work could give patients and clinicians clearer, personalized information to reduce repeat procedures and improve satisfaction with vascular access decisions.

How similar studies have gone: While decision aids exist for dialysis choices, combining large linked registries with machine-learning prognostic models to produce an interactive vascular access guide is relatively new.

Where this research is happening

  • University of California Los Angeles
    Los Angeles, United States
    Active

Researchers

  • Principal investigator: Woo, Karen — University of California Los Angeles
  • Study coordinator: Woo, Karen

Related research

Other NIH-funded projects on the same topics.

  • Improving how patients choose their hemodialysis access

    A patient-friendly project to help people with kidney failure better understand and decide between AV fistula, graft, or catheter for hemodialysis.

    NIH research University of California Los Angeles · Los Angeles, United States · NIH-11400532

  • Improving decision-making for vascular access in hemodialysis patients

    This study is working to make it easier for people with end-stage kidney disease who need hemodialysis to choose the best type of access for their treatment by creating a helpful guide that shows the possible outcomes of different options.

    NIH research University of California Los Angeles · Los Angeles, United States · NIH-10913417

  • Understanding how octopuses integrate sensory information and make decisions

    This study is exploring how octopuses use their arms to grip things by looking closely at their nervous system and movements, which could help us understand their amazing abilities better.

    NIH research Michigan State University · East Lansing, United States · NIH-9949982

  • NoviGuide for Newborn Care in Pakistan

    A small NIH grant to test a pocket-sized decision support tool for nurses and doctors to improve newborn care in Pakistan.

    NIH research Aga Khan University (Pakistan) · Karachi, Pakistan · NIH-11624823

  • Understanding how aging and Alzheimer’s affect how people make tough choices

    This NIH grant studies how aging and Alzheimer’s risk change how people decide between immediate and delayed rewards and risky options, with the goal of helping older adults stay financially and healthwise safer.

    NIH research University of Florida · Gainesville, United States · NIH-11620311

  • Shared decision-making to prevent cancer in South Africa

    A multi-level, school-based program in South Africa helps families, teachers, and health workers make informed choices to prevent cervical and related cancers, especially where HIV is common.

    NIH research Yale University · New Haven, United States · NIH-11603112

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.