Investigating heart issues during dialysis in patients
Official title: Intradialytic Myocardial Stunning in Hemodialysis Patients - a Novel Cardiovascular Risk Factor
Funded at New York University School of Medicine · NIH-10980520 · Data updated 2026-11-12
This study is looking into a heart issue called intradialytic myocardial stunning that affects people on hemodialysis, with the goal of finding out how it leads to heart problems and discovering new ways to help improve their health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | December 24, 2021 |
| Project end | November 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $618,937 |
| NIH project number | 5R01HL157220-04 |
| Project ID | NIH-10980520 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients undergoing hemodialysis, particularly those with a history of cardiovascular issues.
✕Less likely to help
Patients who are not undergoing hemodialysis or those without cardiovascular risk factors may not benefit from this research.
What this research studies
This research focuses on understanding a specific heart condition known as intradialytic myocardial stunning (IdMS) that affects patients undergoing hemodialysis. It aims to explore how this condition contributes to cardiovascular complications, including heart failure and sudden cardiac death, which are prevalent among dialysis patients. The study will analyze various factors that may influence IdMS and its frequency, particularly in high-risk groups that have been underrepresented in previous research. By identifying the mechanisms behind IdMS, the research seeks to uncover new therapeutic targets to improve patient outcomes.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments that significantly reduce cardiovascular-related deaths in hemodialysis patients.
How similar studies have gone: While there have been preliminary studies on similar cardiovascular issues in dialysis patients, this research aims to fill significant gaps and is considered novel in its approach.
Where this research is happening
-
New York University School of Medicine
New York, United States Active
Researchers
- Principal investigator: Charytan, David M — New York University School of Medicine
- Study coordinator: Charytan, David M
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.