NIH-funded research NIH-funded research

Gradual hemodialysis treatment for veterans starting dialysis

Official title: Incremental Hemodialysis for Veterans in the First Year of Dialysis (IncHVets): A Pragmatic, Multi-Center, Randomized Controlled Trial

Funded at Veterans Health Administration · NIH-10975934 · Data updated 2026-11-12

This study is looking at a new way to do hemodialysis for veterans with end-stage kidney disease by starting with fewer sessions each week, so patients can ease into treatment and hopefully feel better overall.

More Randomized Controlled Trial research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionVeterans Health Administration
NIH-funded
Lab location1 site (Long Beach, United States)
Project startOctober 1, 2022
Project endSeptember 30, 2027
Funding year2025
NIH project number5I01CX002382-03
Project IDNIH-10975934 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are veterans who have recently been diagnosed with end-stage renal disease and are beginning dialysis treatment.

Less likely to help

Patients who are not veterans or those who are already established on a full-dose hemodialysis regimen may not benefit from this research.

What this research studies

This research investigates a new approach to hemodialysis for veterans with end-stage renal disease (ESRD) by starting treatment with a less intensive schedule. Instead of the standard thrice-weekly sessions, the study explores an incremental approach that begins with twice-weekly sessions, allowing patients to adjust more comfortably. The goal is to reduce the burden of treatment, improve quality of life, and preserve kidney function for as long as possible. By comparing this method to traditional practices, the research aims to identify potential benefits in patient satisfaction and overall health outcomes.

Why it matters

Potential benefit: If successful, this research could lead to a more patient-friendly dialysis regimen that enhances quality of life and reduces health risks for veterans.

How similar studies have gone: Previous studies have suggested that gradual dialysis approaches may improve patient outcomes, indicating potential success for this novel method.

Where this research is happening

  • Veterans Health Administration
    Long Beach, United States
    Active

Researchers

  • Principal investigator: Kalantar-Zadeh, Kamyar — Veterans Health Administration
  • Study coordinator: Kalantar-Zadeh, Kamyar

Related research

Other NIH-funded projects on the same topics.

  • Gradual dialysis schedules for Veterans new to dialysis

    This trial compares starting dialysis twice-weekly versus the usual three-times-weekly schedule for Veterans beginning dialysis to see if the gentler approach improves quality of life, preserves remaining kidney function, and reduces treatment burdens.

    NIH research Veterans Health Administration · Long Beach, United States · NIH-11212769

  • Cognitive behavioral therapy and trazodone for insomnia phenotypes with high blood pressure

    A clinical study tests how CBT-I and the sleep drug trazodone work for adults with insomnia and high blood pressure, focusing on a specific sleep duration pattern.

    NIH research Pennsylvania State Univ Hershey Med Ctr · Hershey, United States · NIH-11635771

  • Shorter antifungal treatment for kids with candidemia

    A multi-center pediatric trial tests whether a shorter, 7 extra days of antifungal therapy after an initial 7 days is just as good as the standard 14-day approach for kids with candidemia who are improving on echinocandin therapy.

    NIH research Arkansas Children's Hospital Res Inst · Little Rock, United States · NIH-11606539

  • Short Course vs Standard Course Antifungal Therapy for Pediatric Candidemia

    This study tests whether a shorter 7-day total antifungal treatment after an initial 7 days of echinocandin therapy is as effective as the usual 14-day course for children with candidemia.

    NIH research Arkansas Children's Hospital Res Inst · Little Rock, United States · NIH-11606535

  • Shorter antifungal treatment for kids with candidemia

    A multi-center study tests whether kids with candidemia can finish treatment earlier after an initial week of antifungal therapy than the standard two weeks total.

    NIH research Arkansas Children's Hospital Res Inst · Little Rock, United States · NIH-11606531

  • Shorter antifungal treatment for kids with candidemia

    This study tests whether children with candidemia can finish treatment after 7 days of an echinocandin if they are improving, instead of completing a full 14 days.

    NIH research Arkansas Children's Hospital Res Inst · Little Rock, United States · NIH-11606505

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.