Vitamin D3 supplementation for chronic pain relief in hemodialysis patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of high-dose vitamin D3 supplementation on chronic pain in patients undergoing hemodialysis. It is a single-center, double-blind, randomized control trial involving 120 participants who will receive either 576,000 IU of vitamin D3 weekly for four weeks or a placebo. The study will assess pain severity using the Visual Analogue Scale (VAS) and measure various laboratory parameters, including parathyroid hormone levels and vitamin D status. The goal is to determine if vitamin D3 can alleviate chronic pain associated with elevated parathyroid hormone levels in this patient population.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Haemodialysis subject ≥ 20 years old
2. iPTH \> 250 pg/mL
3. Chronic pain with visual analogue scale (VAS) score ≥ 4
4. Voluntary to check serum 25(OH)D levels two times by his/her own payment during the study
5. Sign the informed consent

Exclusion Criteria:

1. Used to participate in other clinical trials
2. Chronic liver disease
3. Sarcoidosis or multiple myeloma

Where it's running

• Taipei Medical University Hospital
  Taipei, Taiwan Recruiting

Study contacts

• Study coordinator: Hsien-Tsung Lu, MD, PhD
• Email: lu7788@tmu.edu.tw
• Phone: +886 2-27372181

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.