IVUS in AV access dysfunction for hemodialysis patients
Official title: Role of Intravenous ultrasound (IVUS) in arteriovenous hemodialysis access dysfunction
Funded at Boston Medical Center · NIH-11378544 · Data updated 2026-11-12
A new approach tests whether using intravascular ultrasound (IVUS) in people with failing AV fistulas or grafts improves diagnosis and guides treatment to prevent more blockages.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Boston Medical Center NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 10, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2026 |
| Award (this year) | $759,459 |
| NIH project number | 5R01DK141016-03 |
| Project ID | NIH-11378544 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with end-stage kidney disease who rely on hemodialysis and have dysfunctional AV access due to stenosis.
✕Less likely to help
Patients without AV access dysfunction or those unable to undergo imaging procedures may not benefit.
What this research studies
This grant explores how IVUS, which creates a three‑dimensional view of the vessel, can more accurately identify stenosis in arteriovenous (AV) access used for hemodialysis. By comparing IVUS to standard angiography, the study aims to improve how doctors determine who needs intervention and what kind of intervention to perform. The goal is to reduce restenosis and improve the durability of AV access for patients with kidney failure who rely on chronic dialysis.
Why it matters
Potential benefit: If successful, patients could experience fewer AV access blockages and longer-lasting dialysis access.
How similar studies have gone: Prior research suggests IVUS can provide better vessel imaging, but this exact application in AV access is being tested.
Where this research is happening
-
Boston Medical Center
Boston, United States Active
Researchers
- Principal investigator: Chitalia, Vipul C — Boston Medical Center
- Study coordinator: Chitalia, Vipul C
Related research
Other NIH-funded projects on the same topics.
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Improving Hemodialysis Access Care with Ultrasound
This project explores how a special ultrasound technique can help doctors better understand and treat problems with hemodialysis access for people with kidney disease.
-
Using ultrasound to improve access for kidney dialysis patients
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.