A new coating for hemodialysis catheters to prevent infections and improve function
Official title: Slippery Omniphobic Coating for Hemodialysis Catheter to Resist Fibrin Sheathing and Infection and Improve Patient Outcomes
Funded at Cerulean Scientific INC. · NIH-10894142 · Data updated 2026-11-12
This study is testing a new coating for hemodialysis catheters that helps prevent infections and improve how well they work, and it's for patients who are undergoing hemodialysis.
Quick facts
| Grant type | Sbir 2 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Cerulean Scientific INC. NIH-funded |
| Lab location | 1 site (Lancaster, United States) |
| Project start | August 1, 2023 |
| Project end | June 30, 2026 |
| Funding year | 2024 |
| Award (this year) | $751,776 |
| NIH project number | 5R44DK135256-02 |
| Project ID | NIH-10894142 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients who are starting hemodialysis and require catheter placement for their treatment.
✕Less likely to help
Patients who are not undergoing hemodialysis or those who use alternative methods for dialysis may not benefit from this research.
What this research studies
This research focuses on developing a special coating for hemodialysis catheters that aims to prevent infections and improve their functionality. The coating is designed to resist the adhesion of bacteria and blood components, which are common causes of complications in patients undergoing hemodialysis. By using a tethered liquid perfluorocarbon coating, the study seeks to reduce the rates of catheter-related bloodstream infections and thrombosis, ultimately enhancing patient outcomes. Patients participating in this research may help test the effectiveness of this innovative approach.
Why it matters
Potential benefit: If successful, this research could significantly reduce the risk of infections and complications associated with hemodialysis catheters, leading to better health outcomes for patients.
How similar studies have gone: While there have been various approaches to improve catheter performance, this specific coating technology is novel and has not been extensively tested in clinical settings.
Where this research is happening
-
Cerulean Scientific INC.
Lancaster, United States Active
Researchers
- Principal investigator: Mcfarland, Todd — Cerulean Scientific INC.
- Study coordinator: Mcfarland, Todd
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.