Sponsor or institution
Clinical trials and research at Medical College of Wisconsin
As of November 12, 2026, Find a Trial lists 97 clinical trials run by Medical College of Wisconsin that are recruiting, at sites in 2 countries (most in United States (97), Nepal (1)). By phase: Phase 2 (21), Phase 1 (8), Early Phase 1 (4), Phase 1/2 (3). There are also 445 NIH-funded research projects at this institution, with $264.9 million in listed awards. Every study is explained in plain English. Data from ClinicalTrials.gov and NIH RePORTER, updated November 12, 2026.
- 97Clinical trials
- 445NIH research projects
- 2Countries
Newest trials
All recruiting trials (97)
-
Immunotherapy with nodal-sparing radiation for head and neck cancer
This study tests whether giving pembrolizumab before and after a focused radiation and surgery plan helps boost the immune response in patients with surgically removable head and neck squamous cell cancer.
-
Stimulating the aging brain with brain and sensory stimulation for language), wait
This study tests whether transcranial alternating current stimulation (tACS) and multisensory stimulation can improve verbal short-term memory in people with Primary Progressive Aphasia.
-
Amnioinfusion during labor to protect neonatal brain in chorioamnionitis
This trial tests whether giving fluid into the uterus during labor for pregnancies affected by chorioamnionitis can help protect the baby’s brain.
-
Protein drinks during labor to help blood sugar stay steadier for pregnant people with insulin-treated diabetes
This study tests whether high-protein beverages during labor help keep a pregnant person’s blood sugar steadier than standard clear liquids when they have diabetes managed with insulin.
-
Ear-based nerve stimulation for children with cyclic vomiting syndrome
This study will try a small ear nerve stimulator to reduce vomiting, nausea, and stomach pain in children who have cyclic vomiting syndrome.
-
Cardiometabolic effects of non-nutritive sweeteners in Type 1 diabetes
This study tests whether non-nutritive sweeteners in a 12-ounce cherry Gatorade drink affect blood sugar control and cardiovascular markers in teens and young adults with Type 1 diabetes.
-
Group singing program combining in-person sessions and instructional videos for people with coronary artery disease
This program will test whether regular group singing, delivered in-person and by instructional videos, can improve blood vessel health in older adults with coronary artery disease.
-
Stimulation plus balance training to improve balance after neck spine compression surgery
This study tests whether adding transcutaneous spinal cord stimulation to balance training helps improve balance in adults who had surgery for degenerative cervical myelopathy.
-
Amnioinfusion to Protect Newborns After Meconium in Amniotic Fluid
This trial tests whether a structured lactated Ringer's amnioinfusion during labor can reduce breathing problems and related complications in babies whose amniotic fluid contains meconium.
-
A 16-week lifestyle program for people with multiple myeloma
We’re testing whether a 16-week eating and exercise plan can improve physical function, quality of life, and aging-related blood markers in adults with multiple myeloma.
-
MitoQ to improve blood vessel function in preeclampsia
This will test whether MitoQ, a mitochondrial antioxidant pill, can improve blood vessel function and help prolong pregnancy in people with preeclampsia.
-
Using a mucosal impedance device to help diagnose chronic esophageal problems
This test tries a mucosal impedance device during upper endoscopy to see if it helps diagnose people with chronic reflux (GERD) or eosinophilic esophagitis.
-
HOPE Biobank: connecting blood disease patients through stem cell transplant and gene therapy samples
This study will collect blood and other biospecimens along with clinical data from people undergoing stem cell transplant or gene therapy for non-cancer blood diseases to build a large biobank for future research.
-
Timing smartphone messages to boost activity for older cancer survivors with chronic pain
This study tests whether sending short smartphone messages at certain times can increase physical activity in older cancer survivors with chronic pain.
-
Pacritinib for metastatic castration-resistant prostate cancer after ARSI
This trial tests pacritinib in adults with metastatic castration-resistant prostate cancer that has progressed after ARSI treatment to see if the drug can help.
-
FT836 CAR T-cell Therapy with Daratumumab in relapsed/refractory multiple myeloma
This phase 1 study tests whether FT836 CAR T cells given with daratumumab are safe and show early signs of activity in adults with relapsed or refractory multiple myeloma who have had at least three prior therapies.
-
Mindfulness with wearables to help prevent high blood pressure problems in pregnancy
This study tests whether adding mindfulness training with wearable biosensors to standard prenatal care can help prevent hypertensive disorders in pregnant people at risk.
-
Self-sampling to improve anal lesion outcomes
This study will test whether people at higher risk for anal cancer will use a self-collected anal swab and whether that increases follow-up cytology and high-resolution anoscopy (HRA) appointment attendance.
-
Postpartum Preeclampsia Early Detection and Treatment in Nepal: A Pilot Study
This pilot study tests whether using sFlt-1/PlGF biomarker testing before delivery can predict postpartum preeclampsia and whether an early monitoring and treatment bundle helps high-risk, postpartum patients.
-
Enfortumab Vedotin in advanced endometrial cancer after prior treatments
A Phase 2 study tests enfortumab vedotin in up to 12 adults with recurrent or metastatic endometrial cancer that has progressed after chemotherapy and immunotherapy.
-
Metformin treatment for premature infants with bronchopulmonary dysplasia
This study tests whether giving metformin to premature infants with bronchopulmonary dysplasia can reduce lung injury and help lungs grow.
-
Blinatumomab consolidation for adults with B‑cell acute lymphoblastic leukemia
This registry collects medical data on adults with B‑ALL who receive blinatumomab as consolidation to see how well it works and how safe it is in routine care.
-
GLP-1 drugs vs. nutrition counseling for Psoriatic Arthritis with obesity and diabetes
This trial compares GLP-1 medications to nutrition counseling to see which approach best helps adults with psoriatic arthritis who also have obesity and type 2 diabetes.
-
Talquetamab bridging therapy followed by ciltacabtagene autoleucel for relapsed/refractory multiple myeloma
This trial tests whether giving talquetamab as a temporary bridging treatment before cilta‑cel is safe and feasible for people with relapsed or refractory multiple myeloma who plan to receive CAR‑T therapy.
-
BCMA-targeted antibody therapy after BCMA CAR T relapse
This study tests linvoseltamab in adults with multiple myeloma who relapsed after BCMA CAR T-cell therapy to see if it can help them respond to treatment.
-
Early versus late esophageal stenting for stubborn benign narrowings
This trial tests whether putting in a temporary esophageal stent early or waiting to use a stent only after repeated dilations work better for people with stubborn benign esophageal strictures.
-
TMS plus language therapy to improve word-finding after left-hemisphere stroke
Researchers will try excitatory transcranial magnetic stimulation combined with semantic feature analysis language therapy to improve word-finding in adults with aphasia after left-hemisphere stroke.
-
MitoQ and ischemic conditioning to improve vascular health after stroke
This project will test whether a brief session of limb ischemic conditioning or taking the antioxidant MitoQ can improve blood vessel function in adults who had a stroke at least six months ago.
-
Pulsed low-dose-rate radiation plus chemotherapy versus standard chemoradiation for esophageal cancer
This trial will test whether delivering radiation as pulsed low-dose-rate together with chemotherapy reduces serious esophagitis compared with standard chemoradiation in adults with locally advanced esophageal adenocarcinoma.
-
UDCA added to standard therapy to prevent C. diff recurrence
This study tests whether taking ursodeoxycholic acid alongside standard antibiotics can reduce recurrence of C. difficile colitis in adults at risk.
-
Personalized neurostimulation for children with gastrointestinal disorders
This study is testing a new treatment that combines personalized nerve stimulation and hypnotherapy to see if it can help children with stomach problems feel better.
-
Wearable AI Device to Guide Daily Pelvic Radiation Timing
A wearable ultrasound device tests whether it can reliably predict when the bladder is full to time pelvic radiation therapy for patients and healthy volunteers.
-
Evaluating pain control methods for postpartum patients with opioid use disorder
This study tests which pain control method works best for new mothers with opioid use disorder to help them manage pain and improve their overall well-being.
-
Mosunetuzumab and Polatuzumab Vedotin with split-dose CHP in older adults with DLBCL
This phase 2 study tests whether adding Mosunetuzumab subcutaneous and Polatuzumab Vedotin to a split-dose CHP chemotherapy regimen helps elderly, newly diagnosed DLBCL patients who are frail or unfit.
-
Using Continuous Glucose Monitoring to Screen for Diabetes in Cystic Fibrosis Patients
This study is testing if using continuous glucose monitors can help better screen for diabetes in people with cystic fibrosis.
-
Improving continence muscle control and strength.
This study will try a small resistance balloon device to strengthen the anal and pelvic floor muscles in adults with weak anal sphincters or healthy volunteers to see if muscle contractility improves and fecal leakage decreases.
-
Bone marrow transplant for severe aplastic anemia
This study is testing if bone marrow transplants from partially matched or unrelated donors can help people aged 3 to 75 with severe aplastic anemia who haven't had treatment before.
-
Combining iadademstat with azacitidine for treating myelodysplastic syndrome
This study is testing a new combination of two drugs, iadademstat and azacitidine, to find the best dose for treating adults with myelodysplastic syndrome.
-
Comparing 5-day versus standard antibiotic treatment for pneumonia in children
This study is testing if a shorter 5-day course of antibiotics is just as effective as the usual 7-14 day treatment for pneumonia in kids aged 3 months to 18 years.
-
Blood flow restriction training for individuals with disabilities
This study tests if a special type of exercise that restricts blood flow can help adults with disabilities keep their muscles strong and healthy when regular workouts are tough to do.
-
Breast screening for people on hormone therapy
This pilot will see if combining mammography and breast ultrasound with surveys and interviews improves screening for people on hormone therapy aged mostly 40–75 (and some 30–39 with family history).
-
Predicting Endocrine Resistance in Breast Cancer Treatment
This study is testing if giving hormone therapy before surgery can help doctors understand how well it works for women with a specific type of breast cancer.
-
Using radiation to delay progression in advanced lung cancer with driver mutations
This study is testing if giving radiation therapy to the main lung tumor can help people with advanced lung cancer and specific gene mutations live longer without their cancer getting worse before they start taking a new medication.
-
Joint intervention for older African Americans with type 2 diabetes and their caregivers
This study is testing a phone-based program to see if it can help older African Americans with type 2 diabetes and their caregivers manage their health better than usual care.
-
Improving health outcomes for older rural adults living with HIV
This study is testing two remote support programs to see if they can help older adults living with HIV in rural areas feel better and stick to their treatment.
-
Personalized therapy for high-risk pancreatic cancer patients after surgery
This study is testing if personalized treatment plans based on the unique characteristics of pancreatic cancer can help high-risk patients feel better and reduce the chance of their cancer coming back after surgery.
-
Controlling blood pressure after preeclampsia to improve heart health
This study is testing if closely managing blood pressure after giving birth can help women who had high blood pressure during pregnancy improve their heart health.
-
Intermittent fasting for women with early breast cancer
This study is testing if a six-month intermittent fasting plan can help women with early breast cancer feel better and improve their health while they start treatment.
-
Using brain stimulation to improve language recovery in stroke patients with aphasia
This study is testing whether a new brain stimulation technique can help stroke survivors with aphasia improve their language skills when combined with speech therapy.
-
Improving diabetes outcomes in formerly incarcerated Black men through nurse case management
This study tests if personalized support from nurse case managers can help formerly incarcerated Black men with type 2 diabetes manage their blood sugar and improve their overall well-being.
-
Improving blood flow and muscle function in stroke survivors
This study is testing if a special treatment can improve blood flow and help leg muscles work better for people who have had a stroke.
-
Integrating community doulas into prenatal care for Black mothers
This study is testing if adding community doulas to prenatal care can help Black mothers have better experiences and health outcomes during pregnancy.
-
Using LV20.19 CAR T-Cells with Pirtobrutinib for B-cell Malignancies
This study is testing a new treatment combining LV20.19 CAR T-cells with pirtobrutinib to see if it helps adults with tough-to-treat B-cell cancers feel better.
-
BCMA-TGFβ CAR-T Cells in Relapsed or Refractory Myeloma
A one-arm phase 1 study tests a new BCMA-TGFβ CAR-T cell therapy to see if it is safe and provides signs of benefit in adults whose multiple myeloma has come back or persisted after prior treatments.
-
Personalized cancer treatment for pancreatic cancer patients
This study is testing if personalized cancer treatments based on tumor testing can help adults with pancreatic cancer respond better to therapy and improve their survival.
-
Improving blood vessel health in frail older adults through exercise and conditioning
This study is testing whether high-intensity exercise and a special conditioning technique can help improve blood vessel health in frail older adults.
-
Observational study for personalized cancer therapy at Medical College of Wisconsin
This study is collecting and analyzing samples from cancer patients at the Medical College of Wisconsin to see how personalized treatments can improve care while making the process easier for everyone involved.
-
Targeted T-Cell and B-Cell Depletion for Hematologic Malignancies
This study is testing a new way to prepare patients with blood cancers for stem cell transplants by removing certain immune cells to see if it helps them recover better and stay healthy longer.
-
Assessing the effects of a pharyngeal exerciser on swallowing
This study is testing how a throat exercise device can help both young and older people swallow better by measuring the pressure in their throats during swallowing.
-
Using a pharyngeal exerciser to improve swallowing in patients with dysphagia
This study is testing if a special device that helps exercise the throat can improve swallowing for people with dysphagia.
-
Modulating esophageal muscle function in healthy individuals and those with swallowing difficulties
This study is testing a new device to see how changing the way we swallow can help healthy people and those with swallowing difficulties move food through their esophagus better.
-
Evaluating pre-treatment vestibular therapy for patients with vestibular schwannomas
This study is testing if doing balance therapy before surgery or radiation can help people with vestibular schwannomas recover better.
-
Using a band to reduce nighttime reflux symptoms
This study is testing if a special band worn around the throat can help people with GERD feel better at night and reduce their reflux symptoms.
-
Understanding how to prevent pharyngeal reflux in GERD patients
This study is trying to understand how the muscles in the throat work in people with GERD to see if they can help prevent reflux from reaching the throat.
-
Understanding challenges and support for African American adults with kidney disease and diabetes
This study looks at the challenges and support African American adults with kidney disease and diabetes face to see how it affects their health and how to help them take better care of themselves.
-
Personalized cancer therapy based on molecular profiling for patients with aggressive malignancies
This study is testing if personalized cancer treatments based on patients' unique tumor profiles can help those with aggressive cancers get better care.
-
Registry to track outcomes in patients with KRAS G12R altered advanced pancreatic cancer treated with MEK inhibitors
This study is tracking how well different combination treatments using MEK inhibitors work for people with advanced pancreatic cancer that has a specific KRAS mutation.
-
Examining how autophagy affects blood vessel function in Type 2 Diabetes
This study is testing if a supplement that boosts a process called autophagy can improve blood vessel function in adults with Type 2 Diabetes.
-
Using sit-stand desks to improve health in sedentary workers
This study is testing if using sit-stand desks can help people with prediabetes, obesity, and metabolic syndrome who have desk jobs improve their health.
-
CD30-targeted bispecific-antibody‑armed autologous T-cell therapy for relapsed CD30-positive blood cancers
This treatment will try using a patient's own T cells armed with a CD30/CD3 bispecific antibody to treat adults with relapsed or refractory CD30-positive blood cancers.
-
Exploring the effects of TMS on language processing in stroke and aphasia
This study tests whether Transcranial Magnetic Stimulation (TMS) can help improve language skills in people who have had a stroke and struggle with aphasia, as well as in healthy individuals.
-
Improving emergency care for sickle cell pain crises
This study is testing a new way to help kids with sickle cell pain crises get the right pain relief faster when they go to the emergency room.
-
Using optical technology to diagnose ear infections in children
This study is testing if a new eye-based technology can help doctors better diagnose ear infections in children compared to the usual methods.
-
Using venetoclax to improve treatment for relapsed or refractory acute myeloid leukemia
This study is testing if adding a drug called venetoclax to existing treatments can help children, teens, and young adults with tough cases of acute myeloid leukemia feel better and have longer-lasting results.
-
High dose re-irradiation for solid tumors using advanced imaging techniques
This study is testing a new way to safely give high doses of radiation again to patients with solid tumors while keeping an eye on any serious side effects.
-
Vagal nerve stimulation for treating symptoms in children with hypermobile Ehlers-Danlos Syndrome
This study is testing two types of non-invasive vagal nerve stimulation therapies to see if they can help reduce gastrointestinal symptoms and improve the quality of life for children with hypermobile Ehlers-Danlos Syndrome.
-
Using a new radiation technique to treat brain metastases
This study is testing a new way of giving radiation to treat brain tumors in adults to see if it helps them tolerate the treatment better and protects their thinking skills.
-
Measuring brain stimulation effects on hand strength in brain tumor patients
This study tests if brain stimulation during surgery can improve hand strength and function in patients with brain tumors affecting the part of the brain that controls movement.
-
Exploring the impact of social relationships on aging in hematopoietic cell transplant survivors
This study looks at how social support and feelings of isolation affect the aging process in people who have survived a stem cell transplant over the course of a year.
-
Treatment-free remission for chronic myeloid leukemia after combination therapy
This study is testing if a combination of two treatments can help people with chronic myeloid leukemia stay in remission without needing more medication after stopping their previous treatment.
-
MRI-guided radiation therapy for rectal cancer organ preservation
This study is testing a new type of MRI-guided radiation therapy for people with advanced rectal cancer to see if it can safely preserve their organs while treating the disease.
-
Blinatumomab treatment after specific stem cell transplant for high-risk leukemia
This study is testing if a new treatment using blinatumomab after a special type of stem cell transplant can help children and young adults with high-risk leukemia stay in remission and live longer.
-
Personalized chemotherapy for pancreatic cancer based on tumor profiling
This study is testing if customizing chemotherapy based on the specific type of pancreatic cancer can help patients with resectable tumors get better treatment results.
-
Fosamprenavir for Laryngopharyngeal Reflux symptoms
This study tests whether the HIV drug fosamprenavir can help people with laryngopharyngeal reflux see if their throat symptoms improve.
-
Using brain stimulation to improve language recovery in stroke patients with aphasia
This study is testing if a new brain stimulation technique can help stroke patients with aphasia recover their language skills better than regular therapy alone.
-
Combination treatment for multiple myeloma patients with kidney issues
This study is testing a new combination treatment for people with multiple myeloma and kidney problems to see if it helps them respond better to therapy before a stem cell transplant.
-
CAR-T cell therapy for patients with relapsed B cell cancers
This study is testing a new CAR-T cell therapy for adults with relapsed B cell cancers to see how well it works and if different manufacturing methods make a difference in treatment outcomes.
-
Using Abemaciclib to treat certain bone and soft tissue sarcomas with specific genetic alterations
This study is testing if the drug Abemaciclib can help people with certain types of bone and soft tissue sarcomas that have specific genetic changes.
-
Monitoring fetal heart activity in high-risk pregnancies to prevent stillbirth
This study is testing a new way to monitor fetal heart activity in high-risk pregnancies to see if it can help prevent stillbirth.
-
Understanding the genetics of autoimmune responses in type 1 diabetes
This study is trying to understand how genes and the environment affect the development of type 1 diabetes by looking at families with a history of the disease and healthy individuals.
-
Botulinum toxin A to treat chemotherapy-related peripheral neuropathy
This trial will try small intradermal injections of IncobotulinumtoxinA (Xeomin) to see if they reduce neuropathic pain in breast cancer patients who developed neuropathy after taxane chemotherapy.
-
Long-term follow-up of patients receiving CAR-T cell therapy
This study is tracking patients who have received CAR-T cell therapy for up to 15 years to see how well the treatment works over time and if there are any long-term health issues.
-
Adaptive chemotherapy approach for pancreatic cancer
This study is testing a flexible chemotherapy plan for people with pancreatic cancer to see if adjusting their treatment based on how well they respond can improve their outcomes.
-
Investigating the best delivery timing for babies with gastroschisis
This study is testing if delivering babies with gastroschisis at 35 weeks is better for their health than waiting until 38 weeks.
-
Analyzing changes during radiation therapy for cancer treatment
This study is testing how changes in tumors and nearby healthy organs during radiation therapy can help doctors improve treatment for cancer patients.
-
Genetic factors and risk of persistent pulmonary hypertension in newborns
This study is trying to see if certain genetic changes in newborns are linked to a higher risk of persistent pulmonary hypertension when their mothers used pain relievers during pregnancy.
-
Investigating genetic factors in diseases affecting premature infants
This study is trying to see if certain genes and biomarkers can help us understand why some premature babies are more likely to develop serious health issues like lung disease and infections.
NIH-funded research (newest 40 of 445)
Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.
-
Finding a cure for sickle cell disease
The Cure Sickle Cell Initiative is bringing together patients, families, and caregivers to work together on finding a cure for sickle cell disease using safe genetic therapies, with the goal of improving lives and speeding up the development of new treatments.
-
A portable device to measure radiation dose and exposure uniformity after a large radiation event
A field-ready, nail-based device uses advanced spectroscopy and smart software to quickly estimate how much radiation a person has received and how evenly they were exposed, within minutes.
-
Ethics of Engaging Patient Groups in Drug Development for Rare Diseases
This grant asks how patient and family groups can ethically help shape rare-disease drug development from idea to market, with input from patients, families, doctors, and researchers.
-
Renovation of the Biophysics Resources at MCW
This grant funds upgrading a core biophysics facility at the Medical College of Wisconsin to support advanced research in human biology.
-
Cure Sickle Cell: Advancing Gene Therapies for Sickle Cell Disease
A national initiative to move safer genetic therapies for sickle cell disease forward with patient, caregiver, and advocate involvement.
-
Health insurance transitions for older adults with HIV on Medicare
Older adults with HIV face complex Medicare coverage that can affect access to HIV treatment and care.
-
How aging cells affect blood vessel growth and tissue repair
This grant studies how aging cells influence the growth of tiny blood vessels to help healing in tissues, with a focus on improving therapies for age-related diseases.
-
Tip60 acetyltransferase: unlocking heart regeneration after a heart attack
Aims to understand how Tip60 enzyme controls heart cell survival and regeneration after a heart attack, with the goal of helping damaged hearts repair themselves.
-
Aldo-keto reductase (AKR) helps brain BH4 levels after injury
This grant tests whether brain AKR enzymes can boost BH4 levels and support better brain function after hypoxia-ischemia-related injury.
-
Regulation of cell state changes in breast cancer
This grant studies how breast cancer cells change their identity during cancer progression to understand and potentially disrupt metastasis and therapy resistance.
-
Keratinocytes and nerve pain in chemotherapy patients
A study tests a new approach to reduce painful nerve damage from chemotherapy by targeting skin cells called keratinocytes.
-
Microbial and Neurovascular Predictors of Early Alzheimer's Subtypes
Researchers will study how gut microbes and brain blood vessel health relate to early stages of Alzheimer's disease and its subtypes to help people understand their risk.
-
FoxA1/2 regulation in human liver formation
A study to understand how FoxA1 and FoxA2 control the first steps of human liver development and how their activity is regulated.
-
Optimal donor choices for stem cell transplants using Bayesian learning in the cyclophosphamide era
A research project will use patient data to help doctors pick the best donor for stem cell transplants in the era of cyclophosphamide-based GVHD prevention.
-
Using smartphones to understand emotion and behavior in autistic teens with depression
A mobile-health study is using daily prompts and passive phone data to learn how emotions and everyday contexts relate to behavior in autistic teens, including those with depression.
-
Knowing What We Eat: Reducing Contaminant Exposure Through Local Lakeside Foods for Anishinaabe Communities
A Native-focused project will help Anishinaabe communities reduce exposure to harmful contaminants by guiding choices about local and subsistence foods.
-
Rat models to study how XX vs XY chromosomes influence disease differences
A NIH grant is funding the creation and validation of rat models that let researchers compare how having XX or XY sex chromosomes affects disease outcomes, independent of hormones.
-
Plasma persulfides and newborn sepsis in babies
A study in newborns, including premature infants and adults, explores whether toxic hydrogen sulfide from gut bacteria explains culture-negative sepsis and if a vitamin B12 derivative could help treat it.
-
Role of GATA6 in SMA pathology
Aims to find new targets to help existing SMA therapies work better for kids and adults with spinal muscular atrophy.
-
Glial gene signatures linked to opioid seeking
A research project explores which glial cell changes are linked to the urge to seek opioids, with the goal of helping people who struggle with opioid addiction.
-
Novel brain renin neurons and blood pressure control
A study to understand how brain cells that make renin could influence high blood pressure and whether targeting them could help treat hypertension.
-
Early-life sodium loss and brain signals that shape long-term heart and metabolism health
This project studies how losing sodium in early life can set the brain’s pressure and salt-checking system to influence heart and metabolic health later on.
-
Ang-II Receptors in AgRP Neurons and Resting Metabolism
A research project aims to understand how a specific brain receptor influences resting metabolism and weight-related biology in adults.
-
Role of B-Arrestin Signaling in Brain Angiotensin Receptor Pathways
A large, multi-year project will explore how a specific signaling pathway (beta-arrestin) at brain angiotensin receptors affects fluid balance and blood pressure in order to improve understanding of brain regulation of cardiometabolic health.
-
Genomics Core: Genetic Mouse Models and Transcriptome Analysis for Cardiovascular Research
A genomics core at a major university provides mouse genetic models and advanced RNA sequencing to support cardiovascular research projects.
-
Core Surgery and Histology Core for brain research in mice
A dedicated core that provides expert surgical and histology support for mouse studies to advance brain and blood pressure research.
-
How the brain’s angiotensin system controls blood pressure and metabolism
A research program will explore how brain angiotensin signaling, especially AT1 receptors, influences blood pressure and metabolic regulation in adults.
-
How brain function and teen drinking influence each other over time
A study following teens and young adults to see how brain function and alcohol use affect each other over several years.
-
How Hormone Therapy Might Affect Breast Cancer Risk and Screening
A doctor-researcher is studying how taking hormone therapy could change a person’s risk of breast cancer and how we screen for it, in adults who use HT.
-
FXR1-carrying extracellular vesicles and their role in bladder cancer microenvironment
This project studies how FXR1 carried by cell-derived vesicles may alter the tumor environment in bladder cancer to support cancer growth and progression.
-
Carbonic Anhydrase as a Heart-Protective Target During Anthracycline Chemotherapy
Aims to protect the heart of breast cancer patients who receive anthracycline chemotherapy by studying a specific enzyme, Carbonic Anhydrase XII, to prevent cardiotoxicity.
-
Redefining when EGFR inhibitors help cancers with mutant RAS
Researchers are studying which cancers with KRAS mutations may still respond to anti-EGFR therapy and how to make that treatment work better for patients.
-
Enhancing early-career leaders in maternal health research
A funded program to train a diverse group of scientists to conduct rigorous maternal health research, including trials involving pregnant and lactating women.
-
Building trust and partnerships to improve pregnancy outcomes for Black women
A large, community-based program in Milwaukee partners with doulas to build trust between Black birthing families and the healthcare system.
-
Housing instability and neighborhood factors affecting maternal health in Black pregnant women
This program looks at how unstable housing and neighborhood conditions influence the health of pregnant Black women and their babies.
-
Addressing social factors that drive gaps in maternal health in Southeastern Wisconsin
A hospital-based program in Milwaukee aims to reduce severe maternal complications by tackling housing instability, medical mistrust, and gaps in postpartum preventive care.
-
Understanding how DNA changes affect genome-regulating genes like BRG1
Researchers are building new ways to interpret how genetic mutations impact diseases by studying how genome-regulating proteins work in 3D and in different body tissues.
-
Symptom Monitoring to Help Women Sticking with Endocrine Therapy
This project tests whether regularly tracking patients' symptoms and having pharmacists help manage them can improve how consistently women with hormone receptor-positive breast cancer take their endocrine therapy over five years.
-
How Laws and Public Opinion Shape People’s Use of HIV Testing and Public Health Measures
This project looks at how people’s beliefs about laws and government requirements affect their willingness to get HIV testing and follow public health guidance.
-
BMT Core at MCW brings advanced CAR T therapy for B-cell cancers
A BMT Core Center at the Medical College of Wisconsin is testing a dual-target CAR T-cell therapy (CD19 and CD20) to help patients with difficult B-cell non-Hodgkin's lymphoma, including mantle cell lymphoma with high-risk features.
Quick answers
How many clinical trials run by Medical College of Wisconsin are recruiting right now?
97, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.
Where are these trials running?
In 2 countries. The most sites are in United States (97 trials), Nepal (1 trial). Each study page lists its sites and which ones are recruiting.
What phases are they in?
Phase 2: 21, Phase 1: 8, Early Phase 1: 4, Phase 1/2: 3. Trials with no phase listed are usually device, behavioural or observational studies.
How do I join one?
Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.
Find the studies that fit you
A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.