Evaluating pain control methods for postpartum patients with opioid use disorder

Evaluating Pain Control Strategies in Postpartum Patients on Opioid Use Disorder Medications: Efficacy and Safety Outcomes.

EARLY_PHASE1 · Medical College of Wisconsin · NCT06617949

This study tests which pain control method works best for new mothers with opioid use disorder to help them manage pain and improve their overall well-being.

Quick facts

PhaseEARLY_PHASE1
Study typeInterventional
Enrollment20 (estimated)
Ages18 Years to 40 Years
SexFemale
SponsorMedical College of Wisconsin (other)
Locations2 sites (Milwaukee, Wisconsin and 1 other locations)
Trial IDNCT06617949 on ClinicalTrials.gov

What this trial studies

This study investigates the effectiveness of three different pain control strategies for postpartum patients who have opioid use disorders. The approaches being evaluated include regional anesthesia, hydromorphone patient-controlled analgesia, and epidural local anesthetic infusion. The goal is to assess which method provides better pain management outcomes and whether it also helps reduce symptoms of anxiety, depression, and improves overall well-being.

Who should consider this trial

Good fit: Ideal candidates for this study are postpartum individuals aged 18-35 who have a diagnosed substance use disorder.

Not a fit: Patients with significant medical conditions that prevent them from receiving the interventions may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could lead to improved pain management strategies for postpartum patients with opioid use disorder, enhancing their recovery experience.

How similar studies have performed: While there is ongoing research in pain management for postpartum patients, this specific approach targeting those with opioid use disorder is relatively novel.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Inclusion criteria include being a parturient with Substance use disorder (SUD) and age 18-35

Exclusion Criteria:

* Exclusion criteria include having a diagnosed medical condition(allergies to medication, pathology such as severe aortic stenosis excluding patients from receiving an epidural etc) that will exempt patient from intervention arm of the study.

Where this trial is running

Milwaukee, Wisconsin and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Substance Use Disorder, Pain conrtrol, Substance use disorder, Parturient

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.