Using optical technology to diagnose ear infections in children

Otitis Media Diagnosis and Treatment: Coherent Optical Detection of Middle Ear Disease

Not applicable Interventional Medical College of Wisconsin · NCT05353569

This study is testing if a new eye-based technology can help doctors better diagnose ear infections in children compared to the usual methods.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment235 (estimated)
Ages12 Months to 6 Years
SexAll
SponsorMedical College of Wisconsin Academic / other
Locations2 sites (Wauwatosa, Wisconsin and 1 other locations)
Trial IDNCT05353569 on ClinicalTrials.gov

What this trial studies

This project aims to evaluate the effectiveness of optical coherence tomography (OCT) as a diagnostic tool for acute otitis media (AOM) and otitis media with effusion (OME) in pediatric patients. The study will compare traditional otoscopy diagnoses with those made using OCT to determine if the latter improves diagnostic accuracy. Given the high prevalence of otitis media in children and its associated complications, the research seeks to enhance diagnostic capabilities, potentially reducing unnecessary antibiotic use and surgical interventions. The study will be conducted in primary care and ENT clinics, focusing on children presenting with ear pain or infection complaints.

Who should consider this trial

Good fit: Ideal candidates include children presenting with complaints of ear infections or ear pain at designated clinics.

Not a fit: Patients with craniofacial abnormalities, immunologic disorders, congenital syndromic conditions, or those with current functioning ear tubes may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to more accurate diagnoses and better management of ear infections in children, reducing complications and healthcare costs.

How similar studies have performed: While the use of OCT in this context is relatively novel, similar diagnostic advancements have shown promise in improving accuracy in other medical fields.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Parental complaint of ear infection or ear pain (Children's Wisconsin Urgent Care Clinics) OR referred for evaluation of otitis media with effusion (Children's Wisconsin ENT Clinic)
* Speak English

Exclusion Criteria:

* Children with craniofacial abnormalities
* Children with diagnosed immunologic abnormalities
* Children with congenital syndromic conditions
* Current open and functioning ear tubes

Where this trial is running

Wauwatosa, Wisconsin and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Otitis MediaOtitis Media With EffusionOtitis Media Acute
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.