Exploring the impact of social relationships on aging in hematopoietic cell transplant survivors
Accelerated Biological and Phenotypic Aging in Hematopoietic Cell Transplant Survivors: Social Support as a Protective Factor
This study looks at how social support and feelings of isolation affect the aging process in people who have survived a stem cell transplant over the course of a year.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 110 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | Medical College of Wisconsin Academic / other |
| Locations | 1 site (Milwaukee, Wisconsin) |
| Trial ID | NCT04892823 on ClinicalTrials.gov |
What this trial studies
This observational study investigates how social support, strain, and isolation affect both biological and phenotypic aging in survivors of hematopoietic cell transplantation (HCT) over a one-year recovery period. Participants will undergo comprehensive assessments at 100 days and one year post-transplant, including self-reports of social interactions and symptoms, as well as biological evaluations through blood samples. The study aims to identify modifiable behavioral factors that could lead to interventions improving quality of life and extending healthspan for these individuals.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18 and older who have received a hematopoietic cell transplant within the last 100 days.
Not a fit: Patients who are younger than 18 years, cannot understand English, or have not received a hematopoietic cell transplant within the specified timeframe will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to interventions that enhance the quality of life and healthspan for hematopoietic cell transplant survivors by addressing social relationship factors.
How similar studies have performed: While the specific approach of this study may be novel, previous research has indicated that social relationships can significantly impact health outcomes, suggesting potential for success.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Aged 18 years and older who are competent to give their informed consent. * Ability to read, speak, and understand English. * Received a hematopoietic cell transplant within the previous 100 days. Exclusion Criteria: * Less then Aged 18 years and older who are competent to give their informed consent. * Cannot read, speak, and understand English. * Has not received a hematopoietic cell transplant within the previous 100 days.
Where this trial is running
Milwaukee, Wisconsin
- Froedtert Hospital and the Medical College of Wisconsin — Milwaukee, Wisconsin, United States (Recruiting)
Study contacts
- Principal investigator: Kelly Rentscher, PhD — Medical College of Wisconsin
- Study coordinator: Medical College of Wisconsin Cancer Center Clinical Trials Office
- Email: cccto@mcw.edu
- Phone: 866-680-0505
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.