Group singing program combining in-person sessions and instructional videos for people with coronary artery disease
Group Singing (Hybrid Format) or Solo Singing in Older Adults With Coronary Artery Disease: A Feasibility Study
NA · Medical College of Wisconsin · NCT07355192
This program will test whether regular group singing, delivered in-person and by instructional videos, can improve blood vessel health in older adults with coronary artery disease.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 32 (estimated) |
| Ages | 55 Years to 89 Years |
| Sex | All |
| Sponsor | Medical College of Wisconsin (other) |
| Locations | 1 site (Milwaukee, Wisconsin) |
| Trial ID | NCT07355192 on ClinicalTrials.gov |
What this trial studies
This pilot interventional program refines and protocols a hybrid group singing intervention and tests the feasibility of a larger trial in older adults with coronary artery disease. Participants will engage in group singing sessions combined with an instructional sing-along video series, with vascular endothelial function measured before and after the intervention. The design builds on a prior randomized crossover study of solo singing that showed improved microvascular endothelial function after a 30-minute instructional video session. The current work focuses on group-based delivery, social inclusion effects, and logistical feasibility for future larger trials.
Who should consider this trial
Good fit: Ideal candidates are older adults with documented coronary artery disease (prior MI, stent/PCI, CABG, ≥50% stenosis, or Agatston score ≥300) who can attend group sessions, follow procedures, and are not current smokers or substance users.
Not a fit: Patients with unstable coronary disease, more than mild cognitive impairment, current tobacco or illicit drug use, supplemental oxygen dependence, or other listed exclusions are unlikely to be eligible or to receive benefit from this program.
Why it matters
Potential benefit: If successful, regular hybrid group singing could improve microvascular endothelial function and reduce long-term cardiovascular risk in older adults with coronary artery disease.
How similar studies have performed: A prior randomized crossover trial of solo singing in people with CAD found a significant improvement in microvascular endothelial function corresponding to an estimated ~25% reduction in CVD risk, while hybrid group-format singing is less studied.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * history of coronary artery disease (defined as having at least 1 of the following: myocardial infarction, coronary stent, PCI, CABG, coronary stenosis at least 50%, or coronary artery calcification score at least 300 Agatston units) Exclusion Criteria: * Parkinson's disease or tremor * upper arm fistula * fingernail onychomycosis * pregnancy * current tobacco use * current illicit drug use * current excessive alcohol use (defined as more than 14 drinks/week for women, more than 28 drinks/week for men) * unstable CAD (active symptoms of chest discomfort) * supplemental oxygen use * more than mild cognitive impairment (as documented in the medical record by patient's treatment teams) * inability to follow study procedures * non-English speaking
Where this trial is running
Milwaukee, Wisconsin
- Medical College of Wisconsin — Milwaukee, Wisconsin, United States (RECRUITING)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Coronary Artery Disease, Elderly, group singing, individual singing