Group singing program combining in-person sessions and instructional videos for people with coronary artery disease
Official title: Group Singing (Hybrid Format) or Solo Singing in Older Adults With Coronary Artery Disease: A Feasibility Study
Run by Medical College of Wisconsin · NCT07355192 · Data updated 2026-11-12
This program will test whether regular group singing, delivered in-person and by instructional videos, can improve blood vessel health in older adults with coronary artery disease.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 55 Years to 89 Years |
| Sex | All |
| Enrollment | 32 (estimated) |
| Sponsor | Medical College of Wisconsin Academic / other |
| Locations | 1 site (Milwaukee, Wisconsin) |
| Status | Recruiting |
| Started | May 11, 2026 |
| Main results expected | February 2028 |
| Study ends | February 2028 |
| Registry record updated | July 13, 2026 |
| Trial ID | NCT07355192 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are older adults with documented coronary artery disease (prior MI, stent/PCI, CABG, ≥50% stenosis, or Agatston score ≥300) who can attend group sessions, follow procedures, and are not current smokers or substance users.
✕Probably not a fit
Patients with unstable coronary disease, more than mild cognitive impairment, current tobacco or illicit drug use, supplemental oxygen dependence, or other listed exclusions are unlikely to be eligible or to receive benefit from this program.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This pilot interventional program refines and protocols a hybrid group singing intervention and tests the feasibility of a larger trial in older adults with coronary artery disease. Participants will engage in group singing sessions combined with an instructional sing-along video series, with vascular endothelial function measured before and after the intervention. The design builds on a prior randomized crossover study of solo singing that showed improved microvascular endothelial function after a 30-minute instructional video session. The current work focuses on group-based delivery, social inclusion effects, and logistical feasibility for future larger trials.
Why it matters
Potential benefit: If successful, regular hybrid group singing could improve microvascular endothelial function and reduce long-term cardiovascular risk in older adults with coronary artery disease.
How similar studies have gone: A prior randomized crossover trial of solo singing in people with CAD found a significant improvement in microvascular endothelial function corresponding to an estimated ~25% reduction in CVD risk, while hybrid group-format singing is less studied.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * history of coronary artery disease (defined as having at least 1 of the following: myocardial infarction, coronary stent, PCI, CABG, coronary stenosis at least 50%, or coronary artery calcification score at least 300 Agatston units) Exclusion Criteria: * Parkinson's disease or tremor * upper arm fistula * fingernail onychomycosis * pregnancy * current tobacco use * current illicit drug use * current excessive alcohol use (defined as more than 14 drinks/week for women, more than 28 drinks/week for men) * unstable CAD (active symptoms of chest discomfort) * supplemental oxygen use * more than mild cognitive impairment (as documented in the medical record by patient's treatment teams) * inability to follow study procedures * non-English speaking
Where it's running
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Medical College of Wisconsin
Milwaukee, Wisconsin, United States Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.