NIH-funded research U01 cooperative agreement

A portable device to measure radiation dose and exposure uniformity after a large radiation event

Official title: A Unique Device to Measure Radiation Dose and Homogeneity of Exposure Following a Large-Scale Ionizing Radiation Event

Funded at Medical College of Wisconsin · NIH-11552312 · Data updated 2026-11-12

A field-ready, nail-based device uses advanced spectroscopy and smart software to quickly estimate how much radiation a person has received and how evenly they were exposed, within minutes.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionMedical College of Wisconsin
NIH-funded
Lab location1 site (Milwaukee, United States)
Project startJuly 7, 2025
Project endMay 31, 2030
Funding year2026
Award (this year)$116,764
NIH project number3U01AI189427-02S1
Project IDNIH-11552312 on NIH RePORTER

Who could benefit from this research

Could help

Individuals exposed to a radiological or nuclear incident who may need dose assessment and triage.

Less likely to help

People not exposed to radiation or for whom the device is not applicable might not benefit from this tool.

What this research studies

In an emergency, this device will let responders measure radiation dose non-invasively by analyzing nail tissue with EPR technology. It will use a lightweight spectrometer, novel probe designs, and fast signal processing to deliver an accurate dose reading (0–10 Gy within ±0.5 Gy) and assess dose homogeneity from nails in about five minutes. The system includes user-friendly software and a neural network to help non-experts operate the device and interpret results for triage decisions. The project combines engineering development with real-world testing to provide a practical biodosimetry tool for radiological incidents.

Why it matters

Potential benefit: If successful, patients and responders could receive rapid, reliable dose information to guide treatment and triage.

How similar studies have gone: Prior biodosimetry approaches exist, but this project aims to deliver a faster, non-invasive and field-ready solution with improved accuracy.

Where this research is happening

  • Medical College of Wisconsin
    Milwaukee, United States
    Active

Researchers

  • Principal investigator: Sidabras, Jason W — Medical College of Wisconsin
  • Study coordinator: Sidabras, Jason W

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.