Clinical trial Recruiting at 1 site Interventional Ages 18 and up

Blood flow restriction training for individuals with disabilities

Official title: Effectiveness of Low Load Resistance Training With Blood Flow Restriction in Individuals With Disabilities

Run by Medical College of Wisconsin · NCT06441422 · Data updated 2026-11-12

This study tests if a special type of exercise that restricts blood flow can help adults with disabilities keep their muscles strong and healthy when regular workouts are tough to do.

Quick facts

Study typeInterventional
Ages18 Years and up
SexAll
Enrollment24 (estimated)
SponsorMedical College of Wisconsin
Academic / other
Locations1 site (Milwaukee, Wisconsin)
StatusRecruiting
StartedDecember 12, 2024
Main results expectedDecember 31, 2026
Study endsDecember 31, 2027
Registry record updatedMay 1, 2026
Trial IDNCT06441422 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults aged 18 and older with disabilities who can perform upper extremity exercises.

Probably not a fit

Patients with uncontrolled hypertension, severe obesity, or certain cardiovascular and neuromuscular conditions may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of low load blood flow restriction training on individuals with disabilities who struggle to engage in standard exercise routines. It aims to determine if this training can mimic the intensity of traditional exercise, thereby helping to maintain muscle mass and overall health. Participants will be divided into two groups: one receiving blood flow restriction training and the other not. The study focuses on individuals aged 18 and older who can perform upper extremity exercises, while excluding those with certain medical conditions.

Why it matters

Potential benefit: If successful, this approach could provide a safer and more accessible way for individuals with disabilities to engage in effective exercise, potentially improving their health outcomes.

How similar studies have gone: While the concept of blood flow restriction training is established, its application specifically for individuals with disabilities is relatively novel and has not been extensively tested.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Male or female
* Age \> or = 18
* English speaking
* Able to understand and perform upper extremity exercises

Exclusion Criteria:

* Pregnant
* Body mass index \>40 kg·m-2
* Uncontrolled hypertension (\>150/90 mmHg)
* Presence of neuromuscular junction and other muscle diseases
* Myocardial infarction in the past 6 months
* Unstable cardiovascular disease
* History of an upper limb deep vein thrombosis
* History of autonomic dysreflexia
* Upper extremity fracture within the last 6 months

Where it's running

  • Medical College of Wisconsin
    Milwaukee, Wisconsin, United States
    Recruiting

Study contacts

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How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.