Improving emergency care for sickle cell pain crises
Sickle Cell Improvement: Enhancing Care in the Emergency Department
This study is testing a new way to help kids with sickle cell pain crises get the right pain relief faster when they go to the emergency room.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 5328 (estimated) |
| Ages | N/A to 18 Years |
| Sex | All |
| Sponsor | Medical College of Wisconsin Academic / other |
| Locations | 1 site (Milwaukee, Wisconsin) |
| Trial ID | NCT05373771 on ClinicalTrials.gov |
What this trial studies
This study aims to enhance the management of sickle cell disease (SCD) pain crises in emergency departments by implementing a structured care pathway. It focuses on ensuring timely administration of pain management as per established guidelines, which are often not followed due to various barriers, including structural racism. The intervention targets children with uncomplicated pain crises who receive opioids during their emergency visits. By addressing these issues, the study seeks to improve patient outcomes and reduce hospitalizations.
Who should consider this trial
Good fit: Ideal candidates for this study are children with sickle cell disease who present to the emergency department with uncomplicated pain crises and receive at least one opioid.
Not a fit: Patients experiencing complications such as acute chest syndrome, fever, priapism, or those with sickle cell trait may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce pain and improve the quality of life for children suffering from sickle cell disease.
How similar studies have performed: Other studies have highlighted the importance of structured pain management protocols in emergency settings, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * ED visit for uncomplicated pain crisis * Sickle cell disease * Receipt of at least one opioid Exclusion Criteria: * Acute chest syndrome * Fever \> 38.5 in the ED * priapism * sickle cell trait
Where this trial is running
Milwaukee, Wisconsin
- Children's Wisconsin — Milwaukee, Wisconsin, United States (Recruiting)
Study contacts
- Principal investigator: David Brousseau, MD, MS — Nemours Children's Health
- Study coordinator: David Brousseau, MD, MS
- Email: david.brousseau@nemours.org
- Phone: (302) 651-4000
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.