Analyzing changes during radiation therapy for cancer treatment
Official title: Intra- and Inter-fraction Changes in Radiation Therapy
Run by Medical College of Wisconsin · NCT02344121 · Data updated 2026-11-12
This study is testing how changes in tumors and nearby healthy organs during radiation therapy can help doctors improve treatment for cancer patients.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 500 (estimated) |
| Sponsor | Medical College of Wisconsin Academic / other |
| Drugs / interventions | radiation |
| Locations | 1 site (Milwaukee, Wisconsin) |
| Status | Recruiting |
| Started | January 2015 |
| Main results expected | December 31, 2027 |
| Study ends | March 20, 2028 |
| Registry record updated | May 6, 2026 |
| Trial ID | NCT02344121 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients who have completed radiation therapy for cancer.
✕Probably not a fit
Patients who refuse voluntary participation will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study aims to analyze and quantify the changes in tumor target volumes and surrounding normal organs during and after radiation therapy. By examining intra-fraction and inter-fraction changes, the research team seeks to enhance the understanding of how Adaptive Radiation Therapy (ART) can be tailored for specific tumor types. The findings will help radiation oncologists select appropriate ART strategies, potentially improving the accuracy of radiation delivery and reducing treatment-related toxicities.
Why it matters
Potential benefit: If successful, this study could lead to more precise radiation therapy techniques that minimize side effects and improve cancer control.
How similar studies have gone: Other studies have shown promise in improving radiation therapy techniques through similar adaptive approaches.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: °Completed radiation therapy Exclusion Criteria: °Subjects who refuse voluntary participation
Where it's running
-
Froedtert Hospital
Milwaukee, Wisconsin, United States Recruiting
Study contacts
- Principal investigator: Eric Paulson, PhD — Medical College of Wisconsin
- Study coordinator: Medical College of Wisconsin Cancer Center Clinical Trials Office
- Email: cccto@mcw.edu
- Phone: 414-805-8900
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.