Clinical trial Recruiting at 1 site Observational

Analyzing changes during radiation therapy for cancer treatment

Official title: Intra- and Inter-fraction Changes in Radiation Therapy

Run by Medical College of Wisconsin · NCT02344121 · Data updated 2026-11-12

This study is testing how changes in tumors and nearby healthy organs during radiation therapy can help doctors improve treatment for cancer patients.

Quick facts

Study typeObservational
SexAll
Enrollment500 (estimated)
SponsorMedical College of Wisconsin
Academic / other
Drugs / interventionsradiation
Locations1 site (Milwaukee, Wisconsin)
StatusRecruiting
StartedJanuary 2015
Main results expectedDecember 31, 2027
Study endsMarch 20, 2028
Registry record updatedMay 6, 2026
Trial IDNCT02344121 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients who have completed radiation therapy for cancer.

Probably not a fit

Patients who refuse voluntary participation will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to analyze and quantify the changes in tumor target volumes and surrounding normal organs during and after radiation therapy. By examining intra-fraction and inter-fraction changes, the research team seeks to enhance the understanding of how Adaptive Radiation Therapy (ART) can be tailored for specific tumor types. The findings will help radiation oncologists select appropriate ART strategies, potentially improving the accuracy of radiation delivery and reducing treatment-related toxicities.

Why it matters

Potential benefit: If successful, this study could lead to more precise radiation therapy techniques that minimize side effects and improve cancer control.

How similar studies have gone: Other studies have shown promise in improving radiation therapy techniques through similar adaptive approaches.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

°Completed radiation therapy

Exclusion Criteria:

°Subjects who refuse voluntary participation

Where it's running

  • Froedtert Hospital
    Milwaukee, Wisconsin, United States
    Recruiting

Study contacts

  • Principal investigator: Eric Paulson, PhD — Medical College of Wisconsin
  • Study coordinator: Medical College of Wisconsin Cancer Center Clinical Trials Office
  • Email: cccto@mcw.edu
  • Phone: 414-805-8900

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.