Condition

Pancreatitis clinical trials and research

• 27Clinical trials
• 109NIH research projects
• 15Countries

Newest Pancreatitis clinical trials

All recruiting trials (27)

• Short-stay aggressive hydration to prevent post-ERCP pancreatitis

  This trial tests whether a short, high-volume IV hydration with Lactated Ringer's plus a rectal indomethacin can prevent post-ERCP pancreatitis in adults undergoing ERCP.

  Recruiting Westmead Hospital · Westmead, New South Wales · NCT07776561

• Phosphate therapy for adults with acute pancreatitis

  This study tests whether giving phosphate through an IV can help adults with acute pancreatitis treated in the emergency department.

  Recruiting Phase 2 Duke University · Durham, North Carolina · NCT07681050

• Cold water rinse plus rectal indomethacin to prevent pancreatitis after ERCP

  This will test whether rinsing the papilla with cold water plus a rectal indomethacin dose lowers the chance of pancreatitis for adults undergoing ERCP.

  Recruiting University of Kansas Medical Center · Kansas City, Kansas · NCT07330284

• Preventing complications after high-risk Whipple (pancreatoduodenectomy) with hydrocortisone, octreotide, and a teres ligament patch

  This tests whether giving hydrocortisone and octreotide around surgery plus placing a teres ligament patch can lower major complications after Whipple surgery in patients with a small pancreatic duct.

  Recruiting Phase 4 Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · Amsterdam · NCT07262957

• Scrambler therapy for chronic pancreatitis pain

  We will test whether Scrambler Therapy can reduce persistent abdominal pain in adults with chronic pancreatitis who haven't found relief from standard treatments.

  Recruiting Johns Hopkins University · Baltimore, Maryland · NCT07174609

• Patient-reported outcomes after pancreatic surgery

  This project will see how pancreatic surgery affects quality of life and whether adults who have pancreatic resection feel satisfied with their decision over time.

  Recruiting at 2 sites University of Arizona · Phoenix, Arizona and 1 other locations · NCT07173257

• Precise endoscopic nitroglycerin to prevent pancreatitis after ERCP

  This trial will try applying a small amount of nitroglycerin during ERCP to see if it lowers the chance of post-ERCP pancreatitis in adults having ERCP with sphincterotomy for bile duct stones.

  Recruiting Phase 4 National Cheng-Kung University Hospital · Tainan, Other (Non U.s.) · NCT07083063

• Indomethacin vs diclofenac to prevent pancreatitis after ERCP

  This trial tests whether a single 100 mg rectal dose of indomethacin or diclofenac given before ERCP better prevents post-ERCP pancreatitis in adults with a native papilla.

  Recruiting at 16 sites Air Force Military Medical University, China · Beijing, Beijing Municipality and 19 other locations · NCT07071441

• Supraglottic oxygen delivery through an endotracheal tube for ERCP under deep sedation

  This tests whether delivering oxygen just above the vocal cords through an endotracheal tube can prevent low oxygen levels in adults having ERCP with deep sedation.

  Recruiting Phase 2 Zhejiang University · Hangzhou, Zhejiang · NCT07051980

• Paracetamol with ibuprofen versus paracetamol with metamizole for pain in children with acute pancreatitis

  We will test whether IV paracetamol combined with ibuprofen or IV paracetamol combined with metamizole reduces pain more effectively in children aged 3–18 with acute pancreatitis.

  Recruiting Phase 4 Medical University of Warsaw · Warsaw · NCT07024199

• Oral microbiota patterns in chronic and autoimmune pancreatitis

  We will sequence mouth bacteria to see if people with chronic pancreatitis or autoimmune pancreatitis have different oral microbiota.

  Recruiting Ruijin Hospital · Shanghai, Shanghai, China · NCT07015580

• COMBO oropharyngeal airway during sedated ERCP

  This test will see if the COMBO Endoscopy Oropharyngeal Airway reduces episodes of low oxygen (hypoxia) in adults undergoing ERCP with propofol sedation.

  Recruiting at 2 sites Phase 2 Zhejiang University · Hangzhou, Zhejiang and 1 other locations · NCT07012772

• Help adults with type 1 diabetes build and keep regular exercise habits

  This project will try a smartphone app plus personalized coaching, fitness-watch data, and continuous glucose monitoring insights to help adults with type 1 diabetes exercise more often and more confidently.

  Recruiting Yale University · New Haven, Connecticut · NCT06967701

• Using deep learning and Raman spectroscopy for early cancer diagnosis

  This study is trying to see if a new deep learning tool using blood samples can help spot early signs of different types of cancer, like colorectal and gastric cancers, in both healthy people and those already diagnosed.

  Recruiting at 4 sites Second Affiliated Hospital, Zhejiang University, School of Medicine · Nanchang, Jiangxi and 3 other locations · NCT06822413

• Evaluating RELiZORB for managing pancreatic enzyme insufficiency in tube-fed patients

  This study is testing if RELiZORB can help tube-fed patients with pancreatic enzyme insufficiency digest food better while they are in the hospital.

  Recruiting Phase 3 Massachusetts General Hospital · Boston, Massachusetts · NCT06691893

• Creating a biobank for studying bilio-pancreatic diseases

  This study is creating a collection of biological samples and health information to see how genes and environment affect the risk of bilio-pancreatic diseases.

  Recruiting IRCCS San Raffaele · Milan · NCT06552078

• Internet program for managing pain in pancreatitis patients

  This study is testing an online program that helps people with pancreatitis manage their pain better and improve their quality of life.

  Recruiting Seattle Children's Hospital · Seattle, Washington · NCT06386224

• Registry of images and videos from endoscopic procedures for pancreatic diseases

  This study is collecting images and videos from endoscopic procedures on patients with pancreatic diseases to help improve how these conditions are understood and treated.

  Recruiting IRCCS San Raffaele · Milan · NCT06344507

• Exploring the role of gut microbiome in gallstone disease

  This study looks at how the bacteria in the gut might affect complications from gallstone disease in adults who are having their gallbladder removed.

  Recruiting East Kent Hospitals University NHS Foundation Trust · Ashford, Kent · NCT05732480

• Using hydrocortisone to treat severe acute pancreatitis

  This study is testing if giving hydrocortisone to people with severe acute pancreatitis can help them recover faster and spend less time in the hospital.

  Recruiting Phase 2 Beth Israel Deaconess Medical Center · Boston, Massachusetts · NCT05160506

• Registry for monitoring CytoSorb device use in critically ill patients

  This study is collecting information on how the CytoSorb device helps critically ill patients to improve care for conditions like septic shock and acute respiratory distress syndrome.

  Recruiting at 24 sites CytoSorbents, Inc · Klagenfurt and 27 other locations · NCT05146336

• Comparing two techniques for accessing the bile duct in patients with biliary diseases

  This study is testing two different methods for accessing the bile duct to see which one works better for patients with biliary diseases like cholangiocarcinoma and choledocholithiasis.

  Recruiting Coordinación de Investigación en Salud, Mexico · Mexico City, Mexico City · NCT04037007

• Evaluating the progression of pancreatitis from acute to chronic stages

  This study is trying to see how acute pancreatitis can turn into chronic pancreatitis over time by following patients with different stages of the condition and using advanced imaging and tests.

  Recruiting at 3 sites Copenhagen University Hospital, Hvidovre · Hvidovre, Capital Region Denmark and 2 other locations · NCT03853447

• Registry for patients with pancreatic diseases

  This study is collecting health information from people with pancreatic diseases to help improve understanding and treatment options for these conditions.

  Recruiting Azienda Ospedaliera Universitaria Integrata Verona · Verona · NCT03807687

• Developing a blood test for early diagnosis of pancreatic cancer

  This study is trying to develop a simple blood test to help find pancreatic cancer early and track how well treatments are working for patients.

  Recruiting at 8 sites Memorial Sloan Kettering Cancer Center · Middletown, New Jersey and 12 other locations · NCT03334708

• Evaluation of chronic pancreatitis for epidemiologic and translational studies

  This study is trying to learn more about what causes chronic pancreatitis and how it gets worse over time by collecting information from patients across the U.S.

  Recruiting M.D. Anderson Cancer Center · Houston, Texas · NCT03099850

• Registry for patients with pancreatic diseases

  This study is creating a registry to collect information from patients with pancreatic diseases to help researchers understand what causes these conditions and how to prevent them.

  Recruiting at 2 sites Icahn School of Medicine at Mount Sinai · New York, New York and 1 other locations · NCT02775461

NIH-funded research (newest 40 of 109)

Early-stage science funded by the US National Institutes of Health. Most of these projects don't enroll patients, but they show what is being worked on.

• Chronic Pancreatitis and Related Conditions Data Center Supports Multi-Center Research

  A national effort to organize and share clinical data and biosamples from people with chronic pancreatitis, pancreatogenic diabetes, and pancreatic cancer to speed biomarker discovery and new treatments.

  NIH research University of Tx Md Anderson Can Ctr · Houston, United States · NIH-11592146

• Lymphatic roles in pancreatitis and recovery

  This project looks at how the lymphatic system influences inflammation and healing in pancreatitis, using mouse models to identify new therapeutic targets.

  NIH research Northwestern University · Chicago, United States · NIH-11425667

• Diabetes after acute pancreatitis: understanding and tracking progression

  A patient-focused look at how diabetes can develop after an episode of acute pancreatitis, using data from a large, ongoing study and AI insights.

  NIH research University of Illinois at Chicago · Chicago, UNITED STATES · NIH-11417492

• Continuation of Type 1 Diabetes in Acute Pancreatitis: UF Health and AdventHealth

  A patient-facing overview of a long-term study tracking people with acute pancreatitis to understand how some develop type 1 diabetes later and what factors influence that process.

  NIH research University of Florida · Gainesville, United States · NIH-11417469

• Data Coordinating Center for Type 1 Diabetes in Acute Pancreatitis Consortium

  A national effort to learn how pancreatitis-related Type 1 diabetes develops, by tracking patients and coordinating data to improve future care.

  NIH research Pennsylvania State Univ Hershey Med Ctr · Hershey, United States · NIH-11417426

• Diabetes after acute pancreatitis: a patient-focused network study

  A program at Indiana University is studying how diabetes can develop after an acute pancreatitis episode, with new findings that could help doctors tailor care for adults who had pancreatitis.

  NIH research Indiana University Indianapolis · Indianapolis, United States · NIH-11416481

• Type 1 Diabetes in Acute Pancreatitis in Diabetes Patients at Stanford

  A Stanford-led project helps people with brittle type 1 diabetes who also experience pancreatitis by following them in a long-term study to understand how acute pancreatitis affects diabetes.

  NIH research Stanford University · Stanford, United States · NIH-11415208

• Malabsorption Blood Test for Exocrine Pancreatic Function in Chronic Pancreatitis

  A blood test (MBT) will help identify people with mild to moderate pancreatic fat malabsorption and show how well enzyme therapy improves their quality of life.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11415052

• Epidemiology and causes of diabetes after acute pancreatitis

  A long-term study following people who have had acute pancreatitis to understand how often diabetes develops, why it happens, and how it progresses.

  NIH research Ohio State University · Columbus, UNITED STATES · NIH-11413812

• Type 1 Diabetes after Acute Pancreatitis: Immune Clues from the Pacific Northwest

  A multi-center study follows adults after an acute pancreatitis episode to understand how some develop Type 1 diabetes and what immune factors are involved.

  NIH research Benaroya Research Inst at Virginia Mason · Seattle, United States · NIH-11413767

• Diabetes After Acute Pancreatitis: Understanding Causes and Care

  A nationwide research effort is studying how diabetes develops after an episode of acute pancreatitis in adults to improve prevention and treatment.

  NIH research University of Minnesota · Minneapolis, United States · NIH-11413733

• Diabetes After Acute Pancreatitis: Building a Center for Better Care

  A patient-focused center studies how acute pancreatitis might lead to brittle diabetes and aims to understand and improve long-term blood sugar health.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11413703

• Diabetes After Acute Pancreatitis: Understanding Progression and Genetics at Cedars-Sinai

  This grant supports Cedars-Sinai’s clinical center as part of a national effort to study why some adults develop brittle type 1 diabetes after an acute pancreatitis episode and how genes influence this risk.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11413637

• Diabetes development after acute pancreatitis: factors, beta cell health, and immune clues

  This project follows people who had acute pancreatitis to see who develops diabetes, why it happens, and how beta cells and the immune system are involved.

  NIH research Johns Hopkins University · Baltimore, United States · NIH-11413528

• Chronic Pancreatitis Clinical Research Cohort and Biorepository

  A long-term study at UF/Advent Health following adults with acute, relapsing, and chronic pancreatitis to build a detailed group with biospecimens and data for better diagnosis and personalized care.

  NIH research University of Florida · Gainesville, United States · NIH-11408761

• Renalase-based therapy for acute pancreatitis

  A new drug approach aims to reduce pain and inflammation for people with acute pancreatitis by using a renalase-like treatment.

  NIH research Bessor Pharma, LLC · Framingham, United States · NIH-11406103

• Cedars-Sinai Center leads research on chronic pancreatitis and pancreatic cancer

  A Cedars-Sinai research center is renewing its program to study chronic pancreatitis, diabetes-related pancreatic disease, and pancreatic cancer so doctors can better understand and treat these conditions.

  NIH research Cedars-Sinai Medical Center · Los Angeles, United States · NIH-11401819

• UPMC Center for Pancreatitis and Diabetes research program

  A specialized center at the University of Pittsburgh is advancing clinical and biological studies of chronic pancreatitis, recurrent acute pancreatitis, and diabetes to improve understanding and care.

  NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11401437

• Chronic Pancreatitis Research Network to Understand Symptoms and Find Treatments

  This project advances studies of chronic pancreatitis to understand why some people progress and to test new ideas that could diagnose or slow the disease.

  NIH research Indiana University Indianapolis · Indianapolis, United States · NIH-11400539

• Chronic Pancreatitis Clinical Research Consortium at Stanford

  A Stanford-based effort is renewing a patient-centered program to study chronic pancreatitis and recurrent acute pancreatitis, with ongoing recruitment of both adult and pediatric participants.

  NIH research Stanford University · Stanford, United States · NIH-11400526

• Pediatric pancreatitis: finding early clues to predict progression and guide therapies

  This project looks at why some children with acute recurrent pancreatitis develop chronic pancreatitis and how to tailor future treatments.

  NIH research University of Iowa · Iowa City, United States · NIH-11400490

• OKPRC: Improving diagnosis and care for chronic pancreatitis

  A program from Ohio State University aims to improve how chronic pancreatitis is diagnosed and treated, through biomarker validation, nutrition research, and clinical trials.

  NIH research Ohio State University · Columbus, UNITED STATES · NIH-11400442

• Chronic Pancreatitis Data Coordinating Center for Coordinated Research

  A nationwide group is coordinating data and biospecimens to better understand chronic pancreatitis and related conditions to improve care.

  NIH research University of Tx Md Anderson Can Ctr · Houston, United States · NIH-11400335

• Pancreas problems in diabetes, pancreatitis, and cancer

  A nationwide group led by Mayo Clinic is joining forces to study how the pancreas is involved in type 2 diabetes, pancreatitis, and pancreatic cancer so providers can diagnose and treat these conditions better.

  NIH research Mayo Clinic Rochester · Rochester, United States · NIH-11400293

• Internet-delivered pain self-management for pancreatitis

  A digital cognitive-behavioral therapy program helps people with recurrent acute or chronic pancreatitis reduce pain and how much it interferes with daily life.

  NIH research Seattle Children's Hospital · Seattle, United States · NIH-11398838

• Safety and pain relief with stem cells for chronic pancreatitis

  Aims to see if stem cell therapy can safely lessen chronic pancreas pain and improve quality of life for people with chronic pancreatitis.

  NIH research Medical University of South Carolina · Charleston, United States · NIH-11380938

• Elucidating how calcineurin signaling drives pancreatitis and identifying new targets

  This NIH grant looks at how a signaling protein called calcineurin contributes to acute pancreatitis and aims to find new ways to block it so patients have milder symptoms.

  NIH research Stanford University · Stanford, United States · NIH-11367438

• One Health approach to a new treatment for acute pancreatitis in people and dogs

  A new drug, RABI-767, is being developed to treat acute pancreatitis in both humans and dogs, aiming to prevent organ failure.

  NIH research Lamassu Pharma INC. · Durham, UNITED STATES · NIH-11360137

• Pancreatic enzyme use to reduce pancreatitis episodes in children

  A study tests whether pancreatic enzyme replacement therapy can cut episodes of pancreatitis and improve quality of life for children with pancreatic-relevant ARP or CP.

  NIH research Research Inst Nationwide Children's Hosp · Columbus, United States · NIH-11346366

• Immune markers that predict who will get severe acute pancreatitis

  Researchers will measure immune system proteins in people admitted with acute pancreatitis to spot early signs of who may become severely ill.

  NIH research Ohio State University · Columbus, UNITED STATES · NIH-11333744

• Diabetes after acute pancreatitis: monitoring blood sugar with continuous glucose sensors

  This project uses wearable continuous glucose monitors to track blood sugar patterns in adults who have had acute pancreatitis to better understand who develops diabetes.

  NIH research Pennsylvania State Univ Hershey Med Ctr · Hershey, United States · NIH-11326762

• Understanding how acute pancreatitis may lead to type 1 diabetes

  This study is looking at how having acute pancreatitis might lead to type 1 diabetes, and it aims to find early warning signs and risk factors to help identify people who could be at risk for developing diabetes after pancreatitis.

  NIH research Pennsylvania State Univ Hershey Med Ctr · Hershey, United States · NIH-11324799

• Looking inside the inflamed pancreas with live imaging

  Researchers are testing whether blocking blood-clotting signals and an enzyme called trypsin can reduce damage in acute pancreatitis using advanced live imaging in mice.

  NIH research Mayo Clinic Jacksonville · Jacksonville, United States · NIH-11322051

• Understanding inherited pancreatitis

  Researchers are using new mouse models that carry human gene changes to learn how inherited pancreatitis starts and why it raises cancer risk for people with PRSS1 mutations.

  NIH research Mayo Clinic Jacksonville · Jacksonville, United States · NIH-11321534

• PKD1 protein's role in turning acute pancreatitis into chronic pancreatitis

  Seeing if blocking a protein called PKD1 can stop acute pancreatitis from turning into chronic pancreatitis.

  NIH research Mayo Clinic Jacksonville · Jacksonville, United States · NIH-11321526

• Targeting specific channels to reduce severe pancreatitis caused by a common virus in children

  This study is looking at how a virus called Coxsackievirus B can harm the pancreas in children and aims to find ways to protect pancreatic cells from damage and inflammation caused by the virus.

  NIH research University of Texas Dallas · Richardson, United States · NIH-11291589

• How trypsin becomes activated in pancreatitis

  This project looks at how the digestive enzyme trypsin starts working inside the pancreas and how that can trigger pancreatitis in people with or at risk for the condition.

  NIH research Boston University Medical Campus · Boston, United States · NIH-11290323

• Understanding how a brain-like immune switch (TREM2) affects chronic pancreatitis

  A patient-friendly look at how a specific immune receptor called TREM2 might control inflammation and tissue damage in chronic pancreatitis, with potential paths toward better treatment.

  NIH research University of Tx Md Anderson Can Ctr · Houston, United States · NIH-11269401

• Soy-and-tomato diet to lower inflammation in chronic pancreatitis

  This project gives people with chronic pancreatitis a soy-and-tomato drink to lower inflammation and help improve nutrition and symptoms.

  NIH research Ohio State University · Columbus, UNITED STATES · NIH-11260254

• How faulty cholesterol control in pancreas cells can cause pancreatitis

  This project explores whether problems with cell cleanup in the pancreas lead to cholesterol buildup in pancreas cells and trigger acute pancreatitis.

  NIH research University of California Los Angeles · Los Angeles, United States · NIH-11245716

Related topics

Quick answers

How many Pancreatitis clinical trials are recruiting right now?

27, as of November 12, 2026. We update this list each time we refresh our data from ClinicalTrials.gov.

Where are these trials running?

In 15 countries. The most sites are in United States (11 trials), China (5 trials), Italy (4 trials), Poland (2 trials), Australia (1 trial). Each study page lists its sites and which ones are recruiting.

What phases are they in?

Phase 2: 4, Phase 4: 3, Phase 3: 1. Trials with no phase listed are usually device, behavioural or observational studies.

How do I join one?

Open a study, check the "Is this trial a fit for you?" section, then contact the study team listed on the page. They will ask a few screening questions. Asking is free and does not commit you to anything. Talk it over with your doctor first.

Find the studies that fit you

A list is a starting point. Tell us your situation in your own words and we'll rank the studies that match and explain why. It's free and needs no account.

Describe your situation →